TWAS
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Forced vital capacity (FVC)
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chr11:76,827,992-78,216,992
Best TWAS P=1.78e-08 · Best GWAS P=4.95e-06 conditioned to 0.299
76.8M
77M
77.2M
77.4M
77.6M
77.8M
78M
78.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
AP000580.1
0.12
0.02
enet
18
0.08
1.1e-06
4.2
-5.6
1.8e-08
0.67
0.06
0.83
TRUE
4
The Cancer Genome Atlas
Thyroid Carcinoma
C11orf67
0.11
0.09
blup
60
0.12
7.8e-12
-4.5
5.4
6.5e-08
-0.89
0.01
0.94
FALSE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
C11orf67
0.07
0.06
enet
8
0.07
1.3e-04
-4.5
5.3
1.3e-07
-0.92
0.01
0.61
FALSE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
C11orf67
0.07
0.04
blup
60
0.04
2.5e-05
-4.3
5.3
1.3e-07
-0.87
0.01
0.85
FALSE