Best TWAS P=1.78e-08 · Best GWAS P=4.95e-06 conditioned to 0.299
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | AP000580.1 | 0.12 | 0.02 | enet | 18 | 0.08 | 1.1e-06 | 4.2 | -5.6 | 1.8e-08 | 0.67 | 0.06 | 0.83 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | C11orf67 | 0.07 | 0.06 | enet | 8 | 0.07 | 1.3e-04 | -4.5 | 5.3 | 1.3e-07 | -0.92 | 0.01 | 0.61 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C11orf67 | 0.07 | 0.04 | blup | 60 | 0.04 | 2.5e-05 | -4.3 | 5.3 | 1.3e-07 | -0.87 | 0.01 | 0.85 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C11orf67 | 0.11 | 0.09 | blup | 60 | 0.12 | 7.8e-12 | -4.5 | 5.4 | 6.5e-08 | -0.89 | 0.01 | 0.94 | FALSE |