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Forced vital capacity (FVC)
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chr11:116,022,447-117,662,909
Best TWAS P=1.9e-08 · Best GWAS P=1.93e-10 conditioned to 4.94e-06
116M
116.2M
116.4M
116.6M
116.8M
117M
117.2M
117.4M
117.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
SIK3
0.04
0.05
lasso
3
0.04
0.00022
-5.6
5.6
1.9e-08
0.38
0.10
0.76
TRUE
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SIK3
0.04
0.04
enet
8
0.03
0.00052
-5.8
-5.4
6.1e-08
-0.53
0.04
0.94
FALSE
1
GTEx
Esophagus Mucosa
SIK3
0.10
0.06
lasso
2
0.04
0.00149
-5.4
-5.2
1.8e-07
-0.39
0.13
0.75
FALSE