Best TWAS P=1.9e-08 · Best GWAS P=1.93e-10 conditioned to 4.94e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | SIK3 | 0.10 | 0.06 | lasso | 2 | 0.04 | 0.00149 | -5.4 | -5.2 | 1.8e-07 | -0.39 | 0.13 | 0.75 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SIK3 | 0.04 | 0.04 | enet | 8 | 0.03 | 0.00052 | -5.8 | -5.4 | 6.1e-08 | -0.53 | 0.04 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SIK3 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.00022 | -5.6 | 5.6 | 1.9e-08 | 0.38 | 0.10 | 0.76 | TRUE |