Best TWAS P=1.49e-08 · Best GWAS P=8.05e-10 conditioned to 0.125
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | THSD4 | 0.24 | 0.10 | lasso | 6 | 0.08 | 2.0e-05 | -4.8 | -5.2 | 1.7e-07 | 0.65 | 0.56 | 0.34 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | MYO9A | 0.19 | 0.02 | lasso | 8 | 0.03 | 9.4e-03 | 4.9 | -5.2 | 1.9e-07 | -0.01 | 0.28 | 0.20 | FALSE |
| 3 | GTEx | Nerve Tibial | MYO9A | 0.13 | 0.13 | lasso | 3 | 0.11 | 2.1e-08 | 5.2 | -5.2 | 1.5e-07 | 0.01 | 0.32 | 0.68 | FALSE |
| 4 | GTEx | Stomach | MYO9A | 0.17 | 0.06 | lasso | 5 | 0.01 | 1.1e-01 | 5.0 | -5.2 | 1.7e-07 | -0.01 | 0.40 | 0.36 | FALSE |
| 5 | GTEx | Testis | CTD-2524L6.3 | 0.10 | 0.02 | enet | 13 | 0.03 | 2.1e-02 | 4.5 | -5.7 | 1.5e-08 | 0.30 | 0.20 | 0.29 | TRUE |