Best TWAS P=1.08e-11 · Best GWAS P=3.89e-16 conditioned to 1.77e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CLK3 | 0.06 | 0.02 | lasso | 7 | 0.02 | 1.8e-02 | -5.5 | 5.4 | 5.4e-08 | 0.08 | 0.04 | 0.87 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | LOXL1-AS1 | 0.28 | 0.09 | lasso | 6 | 0.17 | 1.7e-12 | 2.6 | 5.1 | 2.8e-07 | -0.64 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | LOXL1-AS1 | 0.11 | 0.05 | enet | 11 | 0.10 | 7.3e-09 | 1.5 | 5.3 | 1.2e-07 | -0.41 | 0.83 | 0.08 | FALSE |
| 4 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -6.0 | -6.2 | 6.3e-10 | 0.58 | 0.51 | 0.07 | FALSE |
| 5 | GTEx | Thyroid | LOXL1-AS1 | 0.15 | 0.03 | enet | 40 | 0.03 | 2.6e-03 | -6.0 | 6.8 | 1.1e-11 | -0.33 | 0.12 | 0.22 | TRUE |