TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1)
:
←
→
chr15:98,944,630-101,209,341
Best TWAS P=2.61e-08 · Best GWAS P=6.71e-11 conditioned to 4.56e-08
99M
99.5M
100M
100.5M
101M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cerebellum
SYNM
0.19
0.08
enet
10
0.08
0.00266
4.6
5.6
2.6e-08
0.06
0.24
0.10
TRUE
1
GTEx
Adipose Visceral Omentum
CTD-3076O17.1
0.21
0.00
lasso
6
0.00
0.61800
-4.1
-5.3
9.7e-08
-0.15
0.10
0.20
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
SYNM
0.06
0.04
blup
17
0.03
0.00027
-4.0
5.3
1.4e-07
0.09
0.00
0.26
FALSE