TWAS hub - RSL24D1P6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Sigmoid	0.105	0.053	0.00350	0.088	NA	0.051	NA	0.056	0.0005	NA	0.0071	NA	0.0048
2	GTEx	Small Intestine Terminal Ileum	0.184	0.090	0.00390	-0.012	NA	0.000	NA	-0.013	0.7800	NA	0.3200	NA	0.9500
3	GTEx	Vagina	0.436	0.120	0.00097	-0.012	NA	0.004	NA	0.004	0.7400	NA	0.2600	NA	0.2500

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pain experienced in last month	10.2	17.0	23.3	-4.6	-4.8	-2.5
Qualifications: CSEs or equivalent	7.8	10.4	17.2	4.1	3.6	1.0
Medication for pain relief, constipation, heartburn	6.9	11.8	17.9	-3.2	-4.2	-2.7
Medication for hormone replacement therapy	6.6	7.3	11.7	3.4	3.2	0.3
Headache pain in last month	6.6	11.4	15.3	3.9	3.9	1.9
Financial difficulties in last 2 years	6.5	8.8	13.2	3.6	2.9	2.2
Medication: Paracetamol	6.5	10.0	13.0	2.3	3.5	3.6
Qualifications: NVQ or HND or HNC or equivalent	6.2	7.4	11.7	3.4	3.1	0.9
Age at First Birth	5.9	8.6	11.5	-3.1	-3.4	-2.2
Long-standing illness, disability or infirmity	5.9	9.0	16.1	3.3	4.0	0.2
Ever had hysterectomy (womb removed)	5.7	6.5	9.7	3.1	3.0	0.9
Smoking Status	5.6	13.3	17.8	4.0	4.2	2.5
Medication: Ibuprofen	5.6	6.7	8.9	2.5	3.0	2.3
Lung FEV1/FVC ratio	5.5	27.7	70.7	1.6	3.2	8.4
Other serious medical condition/disability diagnosed by doctor	5.5	7.2	13.1	3.6	2.9	0.4
Taking other prescription medications	5.5	8.5	14.4	3.8	3.3	0.0
Medication: Ibuprofen (e.g. Nurofen)	5.5	6.9	9.6	2.6	3.1	2.1
Medication: Paracetamol	5.4	8.9	12.5	2.3	3.5	3.0
Verbal and Numeric Reasoning (VNR)	4.9	11.8	15.9	-3.7	-4.0	-2.4
Neck or shoulder pain in last month	4.9	7.0	11.7	3.0	3.4	0.7
Irritable Bowel Disease (IBD)	4.8	11.5	17.6	4.2	3.9	1.3
Average weekly fortified wine intake	4.8	5.6	9.4	-2.0	-3.1	-1.8
Ever depressed for a whole week	4.8	5.9	8.9	2.0	3.0	2.2
Mouth/teeth dental problems	4.6	7.1	9.9	-3.2	-3.2	-1.2
Past tobacco smoking	4.4	8.1	11.1	-2.4	-3.3	-2.8
Ulcerative Colitis	4.3	6.3	8.4	2.6	2.9	1.9
Blood Red Count	4.3	41.3	62.9	3.4	7.0	7.9
Father’s age at death	4.3	5.8	9.0	-2.8	-3.0	-0.6
Length of working week for main job	4.3	4.8	7.9	2.3	2.8	1.1
Intelligence (Savage-Jansen 2018)	4.1	12.5	16.7	-3.6	-4.1	-2.8
Qualifications: O levels/GCSEs or equivalent	3.9	6.3	11.5	-2.5	-3.4	-1.1
Ulcerative Colitis (UC)	3.7	7.0	10.3	3.2	2.8	1.7
Crohns Disease (2012)	3.7	5.9	9.7	2.3	3.1	1.6
Townsend deprivation index at recruitment	3.7	5.2	7.7	2.8	2.5	1.3
Fluid intelligence score	3.5	7.4	12.7	-2.7	-3.6	-1.4
Forced expiratory volume in 1-second (FEV1)	3.5	11.9	32.4	1.4	1.2	5.7
Angina (self-reported)	3.5	4.5	13.5	-0.0	-0.3	-3.7
Hearing difficulty/problems: Yes	3.4	5.1	9.2	2.4	3.0	0.8
Age started oral contraceptive pill	3.4	4.3	7.9	-2.0	-2.8	-1.0
Chronotype (morning person)	3.3	7.6	12.6	-3.6	-3.0	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	3.3	10.5	26.9	1.6	1.5	5.2
Age at first live birth	3.3	5.9	7.5	-2.2	-2.7	-2.3
Alcohol usually taken with meals	3.2	5.2	7.7	-1.3	-2.8	-2.5
Mouth/teeth dental problems: Dentures	3.2	5.4	7.4	2.5	2.7	1.6
Unable to work because of sickness or disability	3.2	4.2	7.3	2.7	2.1	-0.9
Angina	3.1	4.1	12.3	0.0	-0.1	-3.5
Current tobacco smoking	3.1	5.1	8.6	2.9	2.4	0.9
Number of incorrect matches in round	3.1	5.1	9.3	3.1	2.4	-0.4
Eye problems/disorders: Cataract	2.9	3.4	5.3	-2.3	-1.8	-1.3
Smoking status: Current	2.9	4.6	7.6	2.8	2.2	1.2
Financial situation satisfaction	2.9	3.6	6.1	2.0	2.5	0.8
Medication: Co-codamol	2.8	3.2	6.5	2.5	1.8	0.1
Comparative body size at age 10	2.8	7.8	12.7	-3.6	-2.7	-1.9
Crohns Disease (2017)	2.7	5.9	8.8	3.0	2.9	0.6
Smoking status: Previous	2.7	4.0	6.5	1.5	2.6	1.8
Bilateral oophorectomy (both ovaries removed)	2.6	3.0	4.5	2.1	2.0	0.7
Medication: Ventolin 100micrograms inhaler	2.6	3.3	5.5	-1.0	-1.8	-2.4
Migraine (self-reported)	2.6	3.3	7.0	2.7	1.6	0.2
Ever taken oral contraceptive pill	2.6	2.9	4.6	1.6	1.3	-2.1
Worrier / anxious feelings	2.5	4.7	8.7	-2.2	-3.0	0.7
Knee pain experienced in last month	2.4	3.7	6.5	2.0	2.5	0.7
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.5	5.6	1.0	1.1	2.4
Qualifications: A levels/AS levels or equivalent	2.3	5.1	6.2	-1.9	-2.3	-2.5
Loud music exposure frequency	2.3	2.5	5.5	1.5	2.3	-0.2
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	3.5	-1.9	-1.5	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.9	13.9	-0.8	-0.4	3.7
Pain type(s) experienced in last month: Hip pain	2.3	2.9	4.4	2.1	1.5	-1.5
Breast Cancer	2.2	5.2	7.0	-1.7	-2.6	-2.4
Number of treatments/medications taken	2.2	4.0	6.1	2.4	2.5	0.2
Serious illness, injury or assault to yourself	2.2	2.7	3.8	1.7	1.9	1.2
Impedance of leg (left)	2.2	10.8	21.6	4.7	2.7	1.8
Asthma (self-reported)	2.2	4.4	10.8	-0.9	-1.3	-3.3
Tinnitus: Yes, now most or all of the time	2.2	2.6	4.0	-2.0	-1.6	-1.1
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	4.2	0.9	1.5	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	4.0	1.4	1.3	2.0
Suffer from ‘nerves’	2.0	3.1	7.3	-1.3	-2.7	-0.5
Ever smoked	2.0	3.4	4.0	1.6	2.0	2.0
Maternal smoking around birth	1.9	2.7	4.4	1.7	2.1	0.9
Hair/balding pattern: Pattern 4	1.9	4.6	7.0	2.7	2.6	0.2
Leg pain on walking	1.9	2.3	3.8	1.6	2.0	0.8
Commuting to job workplace: Car/motor vehicle	1.9	2.1	3.6	1.4	1.9	0.9
Worry (Nagel 2018)	1.8	3.9	7.0	-2.1	-2.6	-0.4
Ovarian Cancer	1.8	2.3	2.9	1.6	1.7	1.3
Pack years adult smoking proportion	1.8	2.7	3.5	1.9	1.8	1.2
Forced vital capacity (FVC)	1.8	7.1	17.7	1.6	0.9	4.2
Happiness	1.8	2.2	2.8	1.4	1.7	1.4
Asthma	1.8	3.6	8.8	-0.8	-1.2	-3.0
Birth weight of first child	1.8	3.3	8.7	0.5	1.0	3.0
Mean time to correctly identify matches	1.8	3.5	5.8	-1.4	-1.6	-2.4
Overall health rating	1.8	3.9	5.6	2.1	2.4	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.3	1.0	2.1	0.9
Osteoporosis (self-reported)	1.8	2.2	6.0	-0.8	-0.3	-2.4
Mean Putamen Volume	1.7	1.9	3.8	1.4	1.9	0.5
Lupus	1.7	2.6	3.9	-2.0	-1.9	-0.5
Hypothyroidism (self reported)	1.7	3.9	5.1	-1.7	-2.3	-1.9
Depression (self-reported)	1.7	2.0	3.3	1.8	1.6	0.5
Peak expiratory flow (PEF)	1.7	3.8	11.0	-0.7	-0.2	3.3
Heart disease (mother)	1.7	2.1	5.2	-0.6	-0.8	-2.3
Back pain experienced in last month	1.7	2.5	3.5	1.9	1.8	0.8
Heart disease (siblings)	1.7	2.0	5.7	-0.5	-0.4	-2.4
Reaction Time	1.6	3.0	4.8	-1.2	-1.7	-2.2
Respiratory disease	1.6	3.5	7.6	-0.9	-1.4	-2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	4.0	1.5	2.0	-0.5
Stomach or abdominal pain in last month	1.6	2.0	3.0	1.7	1.5	0.9
Chronic bronchitis/emphysema (father)	1.6	1.8	4.5	0.4	0.9	2.1
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.4	4.0	1.8	2.0	0.4
Gout (self-reported)	1.6	2.2	3.3	1.8	1.8	-0.2
Medication: Blood pressure	1.6	2.9	6.9	1.1	0.7	-2.6
Hearing aid user	1.6	1.8	2.6	0.8	1.6	1.4
Impedance of whole body	1.6	7.9	10.6	3.3	2.2	2.9
Waist Hip Ratio (WHR)	1.5	6.6	10.5	3.2	2.6	1.5
Medication: Levothyroxine sodium	1.5	2.5	3.6	-1.6	-1.9	-1.2
Illnesses of mother	1.5	1.8	4.7	0.2	0.8	2.2
Medication for cholesterol, blood pressure or diabetes	1.5	2.6	5.7	-1.1	-0.8	2.4
Medication: Allopurinol	1.5	2.0	3.0	1.7	1.7	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	5.0	2.2	1.2	-0.9
Wears glasses or contact lenses	1.5	1.7	4.9	0.3	0.3	-2.2
Time employed in main current job	1.4	1.6	2.4	-1.5	-1.5	-0.7
Falls in the last year	1.4	1.8	3.7	1.9	1.3	-0.2
Hair/balding pattern: Pattern 3	1.4	2.0	4.2	-2.1	-1.1	-0.8
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	3.0	-1.5	-1.7	-1.7
Pulse wave peak to peak time	1.4	1.7	3.2	1.8	1.4	0.2
Chest pain or discomfort	1.4	2.0	3.1	-0.9	-1.5	-1.7
Ever had bowel cancer screening	1.4	1.7	3.9	0.7	0.7	-2.0
Miserableness	1.4	2.4	5.1	1.4	2.3	0.4
Mother’s age at death	1.4	1.7	2.3	-1.5	-1.5	-0.9
High cholesterol (Self-reported)	1.4	2.5	4.5	2.1	1.6	-0.6
Ever had prostate specific antigen (PSA) test	1.4	1.6	3.4	-1.8	-1.1	-0.3
Schizophrenia vs Biploar Disorder	1.3	1.8	4.8	0.6	-0.3	-2.2
Primary Biliary Cirrhosis	1.3	1.9	2.4	1.5	1.2	-1.4
Medication: Cholesterol lowering	1.3	2.0	4.2	1.1	0.8	-2.0
Blood clot in the leg (DVT)	1.3	1.7	2.4	1.5	1.5	0.7
Forced vital capacity (FVC), Best measure	1.3	4.9	12.0	1.4	0.9	3.5
Eye problems/disorders: None of the above	1.3	1.5	2.4	1.0	1.0	1.5
Blood Platelet Count	1.2	14.0	31.1	-3.3	-5.6	-0.5
Lung FVC	1.2	6.2	17.9	-0.7	-0.5	4.2
Impedance of leg (right)	1.2	5.6	12.1	3.5	1.9	1.1
Pulse wave Arterial Stiffness index	1.2	1.4	2.6	-1.6	-1.2	-0.1
Medication: Aspirin	1.2	1.6	1.8	1.3	1.3	-1.1
Medication: Lisinopril	1.2	1.6	3.3	0.9	0.7	-1.8
Commuting to job workplace: Cycle	1.2	1.4	2.3	-1.5	-1.4	-0.3
Heart attack/myocardial infarction (self-reported)	1.2	1.5	2.7	1.3	0.4	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	2.2	1.5	1.5	0.6
Schizophrenia (2018)	1.1	2.3	5.6	0.9	-0.8	-2.4
Major Depression (MDD)	1.1	1.4	1.6	1.3	1.3	0.9
Average weekly spirits intake	1.1	1.3	2.5	1.2	1.6	-0.2
Diabetes (mother)	1.1	1.4	4.1	0.1	-0.2	-2.0
Impedance of arm (left)	1.1	5.1	11.8	1.4	1.3	3.4
Average weekly red wine intake	1.1	1.7	2.0	-1.4	-1.1	-1.4
Medication: Aspirin	1.1	1.4	2.8	0.9	0.8	-1.7
Illnesses of father: None of the above (group 1)	1.1	1.4	2.7	0.9	0.8	1.6
Medication: Atorvastatin	1.1	1.4	2.4	1.5	1.3	-0.3
Pack years of smoking	1.1	1.6	1.9	1.4	1.3	1.1
Alzheimer’s Disease (in father)	1.0	1.1	2.0	1.1	-0.1	-1.4
Rheumatoid Arthritis	1.0	1.4	3.1	-1.0	-1.8	0.3
Tanning	1.0	12.0	25.3	5.0	3.1	-0.9
Age when periods started (menarche)	1.0	2.5	3.5	-1.9	-1.8	-0.8
Heart attack	1.0	1.3	1.8	1.3	0.5	-1.4
Noisy workplace	1.0	1.3	1.7	0.6	1.3	1.3
Medication: Lansoprazole	1.0	1.1	2.8	0.7	1.7	-0.3
Exposure to tobacco smoke at home	1.0	1.1	1.8	0.9	1.4	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	2.1	0.8	1.4	1.4
Medication: Amlodipine	1.0	1.4	3.6	-0.7	0.3	-1.9
Number of full brothers	1.0	1.2	2.8	0.9	1.7	0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	1.5	-1.2	-0.8	1.2
Age at last live birth	1.0	1.4	1.9	-1.2	-1.4	-0.9
Guilty feelings	1.0	1.5	1.9	1.3	1.4	0.9
Alcohol drinker status: Previous	1.0	1.1	1.8	1.3	1.0	-0.8
Alzheimer’s Disease (in mother)	0.9	1.1	1.9	-1.4	-1.1	-0.4
Neuroticism (2016)	0.9	1.3	3.1	1.8	1.0	0.0
Relative age voice broke	0.9	1.4	3.5	0.8	0.3	1.9
Nervous feelings	0.9	1.6	4.3	-0.8	-2.1	-0.1
Had other major operations	0.9	1.1	3.2	-0.1	-0.4	1.8
Impedance of arm (right)	0.9	4.2	9.9	1.4	0.9	3.1
Alcohol intake versus 10 years previously	0.9	1.3	3.0	-1.7	-0.9	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.2	1.2	1.8	-0.1
Prospective memory result	0.9	1.1	1.9	-1.4	-0.9	-0.7
Medication: Omeprazole	0.9	1.0	1.4	1.2	0.8	1.1
Commuting to job workplace: Walk	0.9	1.0	1.5	-0.5	-1.2	1.1
Mineral and other dietary supplements	0.9	1.1	2.1	-0.5	-1.1	-1.4
Number of self-reported non-cancer illnesses	0.9	1.6	2.2	1.5	1.4	-0.9
Commuting to job workplace: Public transport	0.9	1.1	2.2	-1.0	-1.5	-0.2
Fractured/broken bones in last 5 years	0.9	1.2	2.9	0.8	1.7	0.2
Basal cell carcinoma (self-reported)	0.9	1.0	3.1	-0.1	0.2	1.7
BMI	0.8	4.4	7.9	-2.1	-0.9	-2.8
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	3.1	-0.8	-1.8	-1.3
Supplements: Glucosamine	0.8	1.1	1.6	1.0	0.8	1.3
High blood pressure (mother)	0.8	1.2	3.0	0.7	-0.2	-1.7
Had menopause	0.8	1.0	1.4	-1.2	-1.1	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.4	1.0	0.8	1.2
Birth weight	0.8	1.8	4.6	-0.8	-0.6	2.1
Wheeze or whistling in the chest in last year	0.8	1.5	3.0	0.8	0.9	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.8	-1.7	-0.3	0.1
Illnesses of father: Heart disease	0.8	1.1	1.5	-1.2	-0.7	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	2.2	1.5	1.4	0.9
Breast cancer (self-reported)	0.8	0.9	1.3	0.6	1.1	1.1
Depressed Affect (Nagel 2018)	0.7	1.4	2.9	1.0	1.7	0.6
Depression (Nagel 2018)	0.7	1.1	2.1	1.0	1.4	0.0
Body Mass Index (BMI) (2010)	0.7	1.0	2.1	-1.5	-0.7	-0.6
Fasting Glucose	0.7	0.8	1.7	-0.8	-1.3	0.2
Schizophrenia (2014)	0.7	1.5	3.4	0.2	-1.1	-1.8
Blood Eosinophil Count	0.7	5.5	7.0	-2.5	-1.8	-2.7
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.1	0.9	1.5	-0.5
Vitamin and mineral supplements	0.7	1.0	1.7	0.2	1.3	1.1
Multivitamins +/- minerals	0.7	0.9	1.9	-0.8	-1.4	-0.4
Sitting height	0.7	4.9	5.5	2.4	2.2	2.1
Body mass index (BMI)	0.7	2.9	4.7	-2.2	-0.9	-1.8
Medication: Simvastatin	0.7	1.0	1.7	1.0	0.6	-1.3
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.7	0.2	0.9	-1.3
Mood swings	0.7	1.2	2.4	0.6	1.5	0.9
Number of operations (self-reported)	0.7	1.1	1.5	0.8	1.2	1.1
Supplements: Calcium	0.7	0.8	1.4	1.2	0.8	-0.6
HDL Cholesterol	0.6	1.0	2.6	0.6	0.3	1.6
Medication: Metformin	0.6	0.8	1.1	1.0	0.7	-0.9
Qualifications: None of the above	0.6	1.2	2.4	-0.5	1.0	1.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.6	-0.3	-0.7	-1.2
Arm fat percentage (right)	0.6	2.2	4.5	-2.1	-0.8	-1.2
Pulse wave reflection index	0.6	0.8	2.1	0.1	0.4	1.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.8	0.4	0.4	-1.3
High blood pressure (siblings)	0.6	0.9	2.7	-0.0	-0.1	-1.6
Alcohol drinker status: Never	0.6	0.7	1.1	-0.7	-1.0	-0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	1.4	-0.6	-1.2	-0.7
Allergy or Eczema	0.5	1.4	4.1	-0.1	0.2	-2.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.2	0.6	1.1	0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.2	0.6	1.1	-0.0
Hearing difficulty/problems with background noise	0.5	0.8	2.3	0.1	0.2	-1.5
Hair/balding pattern: Pattern 2	0.5	0.6	1.8	-0.1	-1.3	0.0
Allergy	0.5	1.1	3.0	-0.0	-0.5	1.7
Illnesses of siblings	0.5	0.8	1.7	-0.5	-1.3	0.5
Number of live births	0.5	0.7	1.2	-0.1	1.1	0.9
Arm fat mass (right)	0.5	1.9	3.5	-1.9	-0.7	-1.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.0	0.8	1.0	-0.5
Qualifications: College or University degree	0.5	1.6	2.7	-0.7	-1.7	-1.3
Comparative height size at age 10	0.5	2.8	3.4	1.7	1.8	1.5
Had major operations	0.5	0.6	1.4	0.6	0.3	-1.2
Illnesses of siblings: Diabetes	0.5	0.6	1.0	1.0	0.9	-0.2
Arm fat percentage (left)	0.5	2.1	4.6	-2.1	-0.7	-1.1
Diabetes diagnosed by doctor	0.5	0.8	1.1	0.9	0.7	-1.1
Friendships satisfaction	0.5	0.6	0.9	0.6	1.0	0.6
Osteoarthritis (self-reported)	0.5	0.7	0.9	0.8	0.7	1.0
Illnesses of father: High blood pressure	0.5	0.6	0.6	0.7	0.8	-0.7
Average weekly beer plus cider intake	0.5	0.8	2.0	-0.6	-1.4	-0.2
Risk taking	0.5	0.8	1.0	0.7	1.0	0.9
Bipolar Disorder or Schizophrenia	0.4	0.9	1.6	0.5	-0.8	-1.3
HbA1C	0.4	0.4	0.7	0.8	0.7	0.1
Cardiovascular Disease	0.4	1.4	2.1	1.2	0.9	-1.5
Hair Pigment	0.4	12.7	32.4	0.9	2.2	5.7
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.5	0.0	0.2	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.3	-0.6	-1.0	-1.2
Diabetes (self-reported)	0.4	0.6	1.0	0.8	0.3	-1.0
Hip circumference	0.4	1.7	3.0	-1.7	-0.7	-1.3
Breastfed as a baby	0.4	0.5	1.0	-1.0	-0.6	0.2
Leg fat percentage (right)	0.4	1.3	3.5	-0.7	0.2	-1.9
Leg fat mass (right)	0.4	1.5	3.8	-0.8	-0.0	-2.0
Family relationship satisfaction	0.4	0.4	0.8	0.0	0.7	0.9
Medication for cholesterol	0.4	0.6	1.6	-0.5	-1.2	0.3
Arm fat mass (left)	0.4	1.8	3.4	-1.9	-0.5	-1.3
Myopia	0.4	0.6	1.0	1.0	0.7	-0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.9	-0.2	-0.3	1.7
Prostate Cancer	0.3	0.4	0.4	-0.6	-0.6	0.6
Heel T-Score	0.3	2.1	2.6	-1.2	-1.5	-1.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.7	0.9	0.5	-0.8
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.6	0.5	0.3	-0.8
Systolic blood pressure, automated reading	0.3	0.8	2.0	-0.4	-0.4	-1.4
Severe depression (siblings)	0.3	0.3	0.8	0.9	0.2	0.3
High blood pressure	0.3	0.8	2.5	-0.1	0.1	-1.6
Pain all over the body in last month	0.3	0.3	0.6	-0.8	-0.5	-0.2
Medication: Ramipril	0.3	0.4	0.6	0.7	0.8	0.4
Number of children fathered	0.3	0.3	0.7	0.8	0.4	-0.1
Health satisfaction	0.3	0.4	0.8	-0.1	0.6	-0.9
Shortness of breath walking on level ground	0.3	0.4	1.1	-0.3	0.2	1.1
Emphysema/chronic bronchitis	0.3	0.3	0.6	-0.4	-0.4	-0.8
Medication: Seretide 50 evohaler	0.3	0.4	0.5	-0.6	-0.7	-0.5
Hypertension (Self-reported)	0.3	0.8	2.3	-0.2	-0.0	-1.5
Qualifications: nursing, teaching	0.3	0.5	1.0	1.0	0.1	-0.7
Eye problems/disorders: Glaucoma	0.3	0.4	0.7	-0.4	-0.8	-0.5
Irritability	0.3	0.5	1.2	-0.2	1.1	0.5
Diastolic blood pressure, automated reading	0.3	0.8	0.9	0.9	0.8	-0.9
Leg fat mass (left)	0.3	1.0	2.8	-0.5	0.2	-1.7
Bipolar Disorder (2018)	0.2	0.3	0.9	-0.2	-0.3	0.9
LDL Cholesterol	0.2	0.3	0.8	-0.1	0.0	0.9
Blood White Count	0.2	1.6	2.7	1.5	1.6	0.0
Systolic Blood Pressure	0.2	1.2	1.6	1.3	0.9	-1.0
Relative age of first facial hair	0.2	0.4	0.6	-0.6	-0.8	0.5
Diabetes (father)	0.2	0.3	0.7	0.4	0.3	0.8
Leg fat-free mass (left)	0.2	1.0	2.1	-1.5	-0.6	-0.7
Fed-up feelings	0.2	0.3	0.6	0.5	0.8	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	-0.1	-0.4	-0.6
Medication: Atenolol	0.2	0.2	0.3	-0.6	-0.5	-0.4
Leg predicted mass (left)	0.2	0.9	2.2	-1.5	-0.6	-0.6
Waist circumference	0.2	0.6	1.0	-0.5	0.7	-1.0
Neuroticism score	0.2	0.4	0.9	0.4	0.4	0.9
Weight	0.2	1.0	2.4	-1.6	-0.4	-0.7
Lung cancer (father)	0.2	0.3	0.7	-0.1	0.8	-0.3
Standing height	0.2	1.8	4.1	0.9	0.7	2.0
Glaucoma (self-reported)	0.2	0.2	0.4	0.3	-0.3	-0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.5	0.3	0.4	0.7
Pulse rate, automated reading	0.2	0.5	0.6	0.6	0.8	-0.8
Supplements: Vitamin C	0.2	0.2	0.4	-0.1	-0.6	-0.5
Loneliness, isolation	0.2	0.2	0.4	0.3	0.4	-0.6
Medication: Gliclazide	0.2	0.2	0.7	0.3	0.1	-0.8
Average weekly champagne plus white wine intake	0.2	0.3	0.4	0.5	0.2	-0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.7	-0.4	-0.2	0.8
Medication: Bendroflumethiazide	0.2	0.4	0.6	0.6	-0.4	-0.8
Leg fat percentage (left)	0.2	0.9	2.3	-0.1	0.6	-1.5
Arm fat-free mass (left)	0.2	1.0	1.8	-1.0	-0.5	-1.3
Cholesterol lowering medication	0.2	0.3	0.6	0.2	0.3	-0.8
Coronary Artery Disease (CAD)	0.1	0.1	0.3	0.3	0.0	-0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	-0.4	-0.2	-0.3
Height	0.1	1.8	2.2	1.3	1.3	1.5
Hand grip strength (left)	0.1	0.3	0.3	-0.6	-0.4	-0.6
Supplements: Zinc	0.1	0.1	0.1	0.4	-0.3	-0.1
Trunk fat percentage	0.1	0.3	0.7	-0.8	0.2	-0.3
Hand grip strength (right)	0.1	0.2	0.2	-0.5	-0.3	-0.3
Trunk fat mass	0.1	0.4	0.8	-0.9	0.1	-0.6
Trunk fat-free mass	0.1	0.5	0.7	-0.8	-0.5	-0.8
Pulse rate	0.1	0.2	0.5	0.1	-0.4	-0.7
Trunk predicted mass	0.1	0.6	0.7	-0.8	-0.5	-0.9
Tense / ‘highly strung’	0.1	0.1	0.2	0.1	0.5	0.2
Body fat percentage	0.1	0.5	0.7	-0.8	0.3	-0.8
Arm fat-free mass (right)	0.1	0.4	0.7	-0.7	-0.2	-0.8
Whole body fat mass	0.1	0.6	0.9	-0.9	0.1	-1.0
Arm predicted mass (right)	0.1	0.3	0.7	-0.4	0.1	-0.8
Alcohol intake frequency.	0.1	0.3	0.6	-0.6	-0.7	-0.3
Number of full sisters	0.1	0.1	0.1	0.4	-0.2	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.2	0.4	0.3	-0.4
Whole body fat-free mass	0.1	0.5	0.8	-0.9	-0.4	-0.7
Leg fat-free mass (right)	0.1	0.4	1.0	-1.0	-0.3	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.0	-0.4	-0.1
Whole body water mass	0.1	0.6	1.0	-1.0	-0.4	-0.7
Leg predicted mass (right)	0.1	0.4	1.1	-1.1	-0.3	-0.3
Medication: Blood pressure	0.1	0.3	0.6	-0.7	-0.1	-0.5
Basal metabolic rate	0.1	0.5	1.0	-1.0	-0.3	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.2	0.1	0.4
Arm predicted mass (left)	0.1	0.6	1.1	-0.8	-0.4	-1.0
Neuroticism (Nagel 2018)	0.0	0.1	0.1	-0.2	0.2	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.1	0.3	-0.0	-0.1
Neuroticism	0.0	0.1	0.2	-0.4	0.0	0.5
Sensitivity / hurt feelings	0.0	0.1	0.1	-0.3	-0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.1	0.1	-0.2	-0.1	0.4
Worry too long after embarrassment	0.0	0.0	0.1	0.2	0.1	0.1

Hub : Genes

RSL24D1P6

Models

Trait associations