[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) :

chr20:24,532,613-26,307,797

Best TWAS P=1.13e-07 · Best GWAS P=1.63e-07 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia ABHD12 0.09 0.05 enet 13 0.04 2.9e-02 -5.1 -5.3 1.1e-07 0.95 0.06 0.81 TRUE
2 GTEx Cells Transformed fibroblasts ABHD12 0.24 0.33 lasso 4 0.35 6.3e-27 -5.2 -5.2 2.5e-07 0.97 0.05 0.95 FALSE
3 GTEx Cells Transformed fibroblasts GINS1 0.04 0.01 lasso 3 0.01 5.2e-02 -4.3 -5.3 1.4e-07 0.81 0.10 0.82 FALSE
4 GTEx Colon Sigmoid ABHD12 0.17 0.17 lasso 15 0.17 1.0e-06 -5.0 -5.1 2.9e-07 0.88 0.07 0.93 FALSE
5 GTEx Liver ABHD12 0.20 0.20 lasso 19 0.15 7.3e-05 -5.0 -5.3 1.5e-07 0.96 0.09 0.90 FALSE
6 GTEx Ovary ABHD12 0.23 0.04 lasso 8 0.05 1.9e-02 -4.9 -5.3 1.4e-07 0.86 0.08 0.64 FALSE
7 GTEx Spleen PYGB 0.15 0.09 lasso 6 0.04 2.6e-02 -5.0 -5.3 1.2e-07 0.93 0.09 0.80 FALSE
8 GTEx Thyroid VN1R108P 0.05 0.01 lasso 2 0.02 1.8e-02 -4.2 -5.1 3.1e-07 0.84 0.09 0.74 FALSE
9 The Cancer Genome Atlas Glioblastoma Multiforme ABHD12 0.14 0.10 lasso 5 0.13 1.1e-04 -5.0 -5.2 2.5e-07 0.90 0.05 0.90 FALSE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors NINL 0.11 0.03 blup 81 0.07 2.1e-03 4.6 5.2 1.8e-07 -0.94 0.03 0.71 FALSE