TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr2:69,829,251-71,228,388
Best TWAS P=2.05e-07 · Best GWAS P=5.39e-06 conditioned to 0.0233
69.8M
70M
70.2M
70.4M
70.6M
70.8M
71M
71.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells EBV-transformed lymphocytes
FAM136A
0.31
0.12
lasso
7
0.16
5.6e-06
4.2
5.2
2e-07
-0.5
0.02
0.63
TRUE