Best TWAS P=2.3e-10 · Best GWAS P=5.1e-11 conditioned to 0.0432
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | LONRF2 | 0.08 | 0.00 | lasso | 6 | 0.0 | 2.4e-01 | -6.5 | -6.3 | 2.3e-10 | 0.89 | 0.02 | 0.98 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | AC092667.2 | 0.16 | 0.03 | blup | 439 | 0.1 | 2.2e-12 | -4.8 | 5.5 | 2.8e-08 | -0.43 | 0.78 | 0.22 | FALSE |