Best TWAS P=4.56e-28 · Best GWAS P=2.07e-42 conditioned to 1.49e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GYPA | 0.20 | 0.06 | blup | 293 | 0.10 | 4.0e-12 | -3.9 | -7.0 | 3.2e-12 | 0.32 | 1.00 | 0.00 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -9.3 | -9.1 | 1.3e-19 | 0.35 | 0.24 | 0.73 | FALSE |
| 3 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 9.4 | 11.0 | 4.6e-28 | -0.62 | 0.06 | 0.20 | TRUE |
| 4 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -10.2 | 10.3 | 1.1e-24 | -0.39 | 0.34 | 0.05 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 9.0 | -9.2 | 2.8e-20 | 0.24 | 0.35 | 0.48 | TRUE |