TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1)
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chr5:139,781,095-141,214,127
Best TWAS P=4.34e-08 · Best GWAS P=1e-06 conditioned to 0.00295
139.8M
140M
140.2M
140.4M
140.6M
140.8M
141M
141.2M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Breast Mammary Tissue
PCDHB3
0.12
0.00
enet
22
0.04
0.00244
2.2
-5.5
4.3e-08
-0.39
0.05
0.65
TRUE
2
GTEx
Heart Left Ventricle
PCDHB5
0.11
0.05
lasso
3
0.06
0.00053
4.5
5.4
5.9e-08
0.67
0.08
0.53
FALSE