Best TWAS P=7.82e-15 · Best GWAS P=6.88e-17 conditioned to 0.041
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | U91328.21 | 0.18 | 0.00 | lasso | 11 | 0.02 | 0.03530 | -0.56 | 5.6 | 1.9e-08 | -0.27 | 0.08 | 0.55 | FALSE |
| 2 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 0.03000 | 3.76 | 7.8 | 7.8e-15 | -0.50 | 0.10 | 0.71 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | TRIM38 | 0.09 | 0.00 | enet | 21 | 0.02 | 0.00629 | 1.98 | 5.9 | 3.3e-09 | -0.51 | 0.17 | 0.50 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LRRC16A | 0.07 | 0.04 | blup | 288 | 0.03 | 0.00028 | 3.41 | 5.4 | 5.4e-08 | -0.28 | 0.46 | 0.07 | FALSE |