Best TWAS P=1.75e-07 · Best GWAS P=6.06e-08 conditioned to 0.00107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | FDFT1 | 0.09 | 0.02 | lasso | 4 | 0.03 | 6.1e-03 | -4.0 | -5.2 | 2.2e-07 | -0.50 | 0.18 | 0.26 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FAM66A | 0.23 | 0.26 | enet | 29 | 0.30 | 4.7e-39 | -3.2 | -5.2 | 1.7e-07 | -0.49 | 0.36 | 0.35 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | FAM85A | 0.11 | 0.07 | enet | 23 | 0.11 | 4.3e-14 | -3.2 | -5.1 | 2.9e-07 | -0.63 | 0.09 | 0.90 | FALSE |