TWAS hub - CTSK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1240	0.0380	2.2e-09	0.079	0.074	0.094	0.086	0.081	7.6e-10	2.4e-09	1.8e-11	1.1e-10	4.2e-10
2	GTEx	Adrenal Gland	0.1946	0.1047	6.4e-03	-0.008	NA	0.000	NA	-0.007	9.8e-01	NA	3.1e-01	NA	6.6e-01
3	GTEx	Artery Aorta	0.2260	0.0980	6.2e-04	-0.004	NA	0.017	NA	0.012	6.7e-01	NA	3.9e-02	NA	6.7e-02
4	GTEx	Brain Cerebellum	0.1090	0.0500	1.6e-03	0.145	NA	0.087	NA	0.110	4.5e-05	NA	1.6e-03	NA	4.0e-04
5	GTEx	Heart Atrial Appendage	0.1340	0.0540	3.7e-04	0.018	NA	0.053	NA	-0.003	4.9e-02	NA	2.1e-03	NA	4.7e-01
6	GTEx	Pituitary	0.1370	0.0640	2.3e-03	0.142	NA	0.013	NA	0.056	2.0e-04	NA	1.5e-01	NA	1.6e-02
7	GTEx	Testis	0.0660	0.0380	3.2e-03	0.011	NA	0.009	NA	0.004	9.8e-02	NA	1.2e-01	NA	2.1e-01
8	GTEx	Thyroid	0.0550	0.0290	5.2e-03	0.002	NA	0.003	NA	0.002	2.1e-01	NA	1.6e-01	NA	2.0e-01
9	GTEx	Whole Blood	0.1160	0.0460	3.6e-06	0.032	NA	0.034	NA	0.020	6.2e-04	NA	3.7e-04	NA	5.2e-03
10	NTR	Blood	0.0314	0.0141	3.9e-06	0.024	0.020	0.022	0.022	0.022	2.5e-08	2.5e-07	8.1e-08	9.3e-08	9.3e-08
11	YFS	Blood	0.4474	0.0530	0.0e+00	0.394	0.404	0.418	0.407	0.415	2.3e-139	2.9e-144	1.5e-150	2.5e-145	2.4e-149
12	TCGA	Prostate Adenocarcinoma	0.0549	0.0274	1.1e-03	0.033	0.024	0.020	NA	0.024	2.0e-04	1.5e-03	3.0e-03	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12
Blood Eosinophil Count	8.1	62.5	156.2	-0.1	12.5	-1.2	10.1	-5.6	9.7	7.3	7.6	12.0	10.4	-1.0
Lung FVC	8.1	41.3	82.0	-3.1	2.3	-2.6	8.6	-7.7	8.8	9.1	5.0	8.7	8.5	-3.3
Forced vital capacity (FVC), Best measure	8.0	29.3	50.4	-4.0	1.2	-5.4	6.4	-6.7	7.1	7.1	3.6	6.8	6.7	-3.8
Mouth/teeth dental problems: Mouth ulcers	7.1	11.2	23.7	-0.0	2.2	-2.9	4.6	-3.3	4.2	4.9	3.5	4.3	4.0	-1.1
Prostate Cancer	6.8	9.5	32.0	4.2	1.1	2.9	-1.7	5.0	-1.6	0.8	-3.7	-1.8	-2.7	5.7
Angina (self-reported)	5.5	7.3	13.7	1.7	-1.3	2.1	-3.3	2.9	-3.4	-3.7	-2.7	-3.1	-3.6	1.8
Forced vital capacity (FVC)	5.4	20.6	51.6	-2.0	1.3	-4.5	5.7	-5.1	6.3	7.2	2.0	6.0	5.3	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	5.4	17.2	28.4	-3.7	0.3	-4.3	4.7	-5.3	5.2	4.9	2.9	5.2	5.0	-3.5
Angina	5.2	6.8	12.9	1.7	-1.0	2.2	-3.2	3.1	-3.2	-3.6	-2.5	-2.9	-3.4	2.0
Coronary Artery Disease (CAD)	5.1	6.1	13.8	-0.5	-2.9	2.4	-3.4	1.5	-3.1	-3.7	-2.7	-2.5	-2.8	-0.2
Illness, injury, bereavement, stress in last 2 years	4.4	5.3	10.9	-0.5	2.8	-1.1	2.9	-2.2	3.0	2.9	2.8	2.1	3.3	-0.9
Illnesses of mother	4.2	5.2	13.5	-3.2	-0.4	-3.6	0.6	-3.2	1.7	1.2	1.8	0.8	2.7	-3.7
Irritable Bowel Disease (IBD)	4.1	9.7	29.4	-0.6	-4.1	1.5	-3.9	1.1	-3.9	-5.4	-2.7	-3.9	-3.5	-1.0
Pulse rate, automated reading	4.1	13.2	25.3	-3.0	1.7	-5.0	3.4	-5.0	3.7	2.4	4.5	2.5	4.7	-4.0
Number of operations (self-reported)	4.0	5.9	8.7	-2.2	0.9	-2.9	2.8	-2.9	2.7	2.9	2.4	2.5	3.0	-2.1
Chronotype (morning person)	3.9	9.1	21.0	-4.2	-3.7	-2.2	-3.1	-1.4	-2.6	-4.6	-1.2	-3.5	-2.2	-3.9
Forced expiratory volume in 1-second (FEV1)	3.9	13.3	27.8	-2.3	0.6	-3.9	4.4	-4.4	4.9	5.3	2.2	4.7	4.1	-2.1
Mouth/teeth dental problems: Dentures	3.8	6.3	12.9	2.0	-1.8	2.0	-2.2	3.0	-2.6	-2.1	-2.6	-3.6	-3.6	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.6	7.6	13.2	-2.9	-0.6	-1.2	3.4	-3.6	3.6	3.6	2.3	3.2	3.3	-2.2
Tanning	3.4	41.1	78.5	0.3	7.8	-3.8	8.0	-4.6	8.6	8.9	7.0	8.0	8.1	-1.0
Pulse rate	3.4	5.7	10.8	-1.7	1.1	-3.3	2.7	-3.0	2.7	2.1	2.5	1.8	3.3	-2.4
Medication: Blood pressure	3.4	6.4	18.4	4.3	-0.4	1.7	-1.0	3.6	-1.9	0.3	-2.0	-2.2	-3.3	4.3
Crohns Disease (2017)	3.1	6.8	18.0	0.6	-2.8	2.3	-3.0	1.9	-3.2	-4.2	-2.7	-3.2	-3.2	0.4
Basal cell carcinoma (self-reported)	3.1	3.6	6.9	0.7	-2.0	0.4	-2.5	2.5	-2.6	-2.3	-2.4	-1.9	-2.0	0.9
Qualifications: CSEs or equivalent	3.0	4.0	13.2	-0.9	-1.3	0.3	-3.5	1.5	-2.7	-3.6	-2.6	-1.0	-1.7	-0.5
Peak expiratory flow (PEF)	3.0	7.1	12.0	-1.9	1.6	-2.6	2.8	-3.0	3.3	3.2	2.6	3.4	3.5	-1.9
Systolic Blood Pressure	2.9	14.4	25.5	3.8	-2.0	3.7	-3.0	5.0	-4.2	-2.2	-3.8	-5.0	-5.0	4.5
Impedance of leg (right)	2.9	13.9	28.5	2.1	-1.2	2.7	-5.0	4.6	-4.9	-5.3	-3.7	-4.3	-4.2	2.2
Commuting to job workplace: Walk	2.9	3.1	6.8	0.5	-2.1	1.0	-1.8	1.4	-1.9	-2.1	-2.3	-2.4	-2.6	0.6
Breast Cancer	2.8	6.8	15.8	-2.1	0.8	-2.7	2.9	-3.3	2.8	1.8	4.0	2.3	3.1	-2.8
Medication: Ramipril	2.8	3.5	8.6	1.4	-1.0	1.5	-1.6	1.8	-2.5	-1.9	-2.0	-2.9	-2.7	1.2
Commuting to job workplace: Car/motor vehicle	2.8	3.2	9.0	-0.3	-1.6	1.0	-3.0	1.6	-2.6	-2.6	-1.9	-1.6	-2.0	0.2
Vascular/heart problems diagnosed by doctor	2.8	7.6	15.9	-3.8	1.6	-2.0	1.3	-3.5	2.5	0.7	2.9	3.2	4.0	-3.8
Ulcerative Colitis (UC)	2.7	5.1	14.5	-1.1	-3.3	0.2	-2.9	0.1	-2.8	-3.8	-1.4	-3.0	-2.5	-1.4
Leg pain on walking	2.7	3.4	7.5	1.5	-1.2	1.2	-1.9	2.1	-2.2	-2.1	-1.8	-2.3	-2.7	1.6
Mean Putamen Volume	2.6	3.0	6.6	0.2	-1.4	1.2	-2.6	1.9	-2.5	-2.4	-1.9	-1.4	-2.1	0.5
Blood Platelet Count	2.5	29.1	80.1	1.5	4.9	-4.2	8.8	-4.0	7.6	8.9	5.5	4.3	4.8	0.7
Systolic blood pressure, automated reading	2.5	7.1	13.6	2.0	-1.5	2.7	-2.5	3.7	-3.1	-2.3	-2.6	-3.0	-3.6	2.8
Primary Biliary Cirrhosis	2.3	3.3	8.8	-0.9	1.4	-0.2	1.8	-1.8	2.1	2.4	1.5	3.0	2.8	-1.2
Average weekly fortified wine intake	2.3	2.7	6.4	-0.5	1.2	-1.2	2.2	-1.5	2.5	2.2	1.3	2.5	1.8	-0.7
High blood pressure	2.3	6.3	15.5	3.7	-1.2	1.6	-0.9	3.4	-1.9	0.1	-2.6	-2.5	-3.6	3.9
Stomach or abdominal pain in last month	2.3	2.8	6.6	-2.6	0.1	-0.5	1.0	-2.3	1.4	-0.3	1.6	2.4	2.3	-2.2
Heart attack	2.3	3.0	5.9	1.8	-1.2	0.3	-2.1	1.3	-2.2	-1.9	-2.4	-2.4	-2.0	1.0
Medication: Aspirin	2.3	3.0	6.4	0.9	-1.5	1.3	-2.1	1.5	-2.2	-1.9	-1.7	-2.4	-2.5	0.9
Ulcerative Colitis	2.2	3.2	9.3	-2.6	-3.0	-1.1	-1.4	-1.6	-1.1	-2.6	-0.1	-1.3	-0.6	-2.7
Hand grip strength (left)	2.2	5.8	16.5	-1.0	0.8	-2.7	3.3	-2.3	3.5	4.1	1.6	2.7	2.3	-0.7
Ever used hormone-replacement therapy (HRT)	2.2	2.7	8.4	1.4	-1.3	0.9	-1.5	1.6	-2.1	-1.0	-1.6	-2.9	-2.4	1.2
Vitamin and mineral supplements	2.2	3.0	6.5	-0.0	2.5	-1.1	2.3	-0.8	2.2	2.4	2.1	1.6	2.3	-0.0
Birth weight of first child	2.2	3.9	9.5	-0.9	1.8	-1.1	2.5	-1.7	2.5	2.3	2.6	3.1	2.2	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.4	5.6	1.0	-0.3	2.4	-2.0	2.2	-2.0	-0.9	-1.1	-1.4	-1.6	1.7
Diabetes (mother)	2.0	2.5	7.4	2.3	1.6	2.6	1.4	1.5	0.6	1.3	-0.4	1.2	-0.5	2.7
Impedance of leg (left)	2.0	9.7	23.8	2.0	-0.6	2.2	-4.1	3.7	-4.1	-4.9	-2.9	-3.9	-3.2	1.7
Noisy workplace	2.0	2.4	5.6	0.3	-1.5	1.8	-1.3	1.3	-1.9	-2.4	-1.3	-1.8	-2.3	0.4
Heart attack/myocardial infarction (self-reported)	2.0	2.6	5.5	1.7	-1.1	0.3	-2.0	1.2	-2.0	-1.8	-2.2	-2.4	-1.9	0.9
Heart disease (siblings)	2.0	2.4	6.4	1.8	-0.6	1.8	-0.8	1.8	-1.3	-1.3	-0.7	-1.9	-2.5	2.0
Waist Hip Ratio (WHR)	1.9	8.3	24.5	5.0	0.6	3.8	-1.4	3.9	-2.0	-1.7	-1.4	-3.0	-3.1	4.0
Hypertension (Self-reported)	1.9	5.2	13.0	3.4	-1.2	1.5	-0.8	3.1	-1.8	0.1	-2.4	-2.3	-3.3	3.6
Medication for cholesterol	1.9	2.9	12.0	-3.5	-0.1	-1.7	0.0	-2.2	0.9	-0.5	1.0	1.3	1.6	-3.0
Crohns Disease (2012)	1.8	2.9	8.8	0.3	-1.8	1.2	-2.1	1.1	-2.1	-3.0	-2.0	-2.1	-1.9	0.1
Age when periods started (menarche)	1.8	4.4	9.8	-1.7	1.7	-3.1	1.4	-2.0	2.2	1.6	1.7	3.1	3.0	-1.6
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	5.3	-2.1	-0.0	-1.7	1.0	-2.1	1.3	0.6	1.3	0.4	0.7	-2.3
Alcohol usually taken with meals	1.8	3.0	11.6	-1.2	1.1	-3.4	1.5	-2.2	1.6	1.7	1.6	0.8	1.7	-1.7
Had other major operations	1.8	2.2	5.8	-0.4	0.5	-1.5	2.1	-1.2	2.0	2.4	1.2	1.8	1.7	-0.3
Medication: Blood pressure	1.8	3.2	7.6	0.2	-1.3	0.8	-2.1	1.6	-2.1	-2.3	-2.1	-2.8	-2.6	0.6
Medication: Aspirin	1.8	2.3	5.0	0.8	-1.2	1.2	-1.8	1.2	-1.9	-1.8	-1.6	-2.1	-2.2	0.8
Ovarian Cancer	1.7	2.3	7.5	1.8	0.2	2.7	-1.3	2.0	-1.5	-0.8	-0.8	-0.9	-1.8	2.0
Trunk fat percentage	1.7	6.6	29.6	-2.2	-1.8	1.6	-4.1	1.3	-2.7	-5.4	-2.2	-0.6	-2.5	-1.4
Multivitamins +/- minerals	1.7	2.2	4.0	0.8	-1.2	1.5	-2.0	1.6	-2.0	-1.8	-1.6	-1.2	-2.0	1.0
Body fat percentage	1.7	6.6	28.7	-1.6	-1.4	2.2	-4.1	1.8	-2.8	-5.4	-2.1	-0.8	-2.7	-0.9
Ever taken oral contraceptive pill	1.7	1.8	5.2	0.1	-0.9	2.3	-1.5	1.9	-1.6	-1.2	-1.0	-1.0	-1.8	1.0
Pain type(s) experienced in last month: Hip pain	1.7	2.1	5.7	0.6	-0.5	1.9	-2.4	2.0	-2.2	-1.6	-0.9	-0.7	-1.4	1.1
Impedance of arm (right)	1.6	7.3	26.7	-0.6	-2.2	-0.1	-4.5	1.8	-3.6	-5.2	-2.8	-2.4	-2.4	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.0	0.2	1.8	-1.2	1.8	-0.9	1.8	1.9	1.2	2.0	1.5	-0.2
Average weekly champagne plus white wine intake	1.6	2.2	8.1	-0.5	1.0	-1.3	1.9	-1.4	1.9	2.8	1.2	1.5	1.5	-0.3
Medication: Atorvastatin	1.6	1.9	6.1	2.5	0.2	1.3	-0.8	1.7	-1.0	-0.6	-0.8	-1.7	-1.7	1.9
Impedance of whole body	1.6	8.4	28.6	0.4	-1.2	1.4	-4.5	2.7	-3.9	-5.3	-2.7	-3.3	-2.8	0.3
Hearing difficulty/problems: Yes	1.5	2.3	11.2	1.3	3.3	1.8	1.1	1.1	1.0	0.6	0.3	2.1	0.8	1.6
Serious illness, injury or assault to yourself	1.5	1.8	4.1	-0.3	-1.4	0.8	-1.8	1.2	-1.9	-1.7	-0.9	-2.0	-1.8	0.2
High blood pressure (mother)	1.5	2.1	5.8	2.3	0.4	2.0	0.3	1.8	-0.8	-0.6	-0.9	-0.9	-2.0	2.4
Time employed in main current job	1.5	1.7	3.4	-0.8	1.5	-1.1	1.5	-1.1	1.8	1.3	1.4	1.6	1.8	-0.8
Alcohol intake versus 10 years previously	1.5	2.3	4.6	1.6	-0.3	1.9	-1.6	2.1	-1.4	-1.1	-1.4	-1.3	-1.9	1.9
Worry too long after embarrassment	1.5	2.4	6.6	0.3	2.6	0.1	1.8	-1.2	2.0	1.9	1.4	2.2	1.8	-0.1
Tinnitus: Yes, now most or all of the time	1.5	1.8	3.5	-1.9	0.0	-0.9	1.0	-1.9	1.3	0.7	1.2	1.5	1.9	-1.9
Cardiovascular Disease	1.4	4.5	9.3	2.9	-1.6	1.9	-1.1	3.0	-1.9	-0.5	-1.7	-1.9	-3.0	3.0
Medication: Lansoprazole	1.4	1.6	3.4	0.7	-0.6	0.7	-1.8	1.3	-1.6	-1.0	-1.3	-1.8	-1.6	1.0
Lung cancer (father)	1.4	1.6	4.1	0.6	0.0	-0.1	-1.3	1.4	-1.7	-1.7	-1.2	-2.0	-1.8	0.6
Leg fat percentage (right)	1.4	5.2	19.0	-0.4	-0.9	2.9	-3.3	2.4	-2.5	-4.4	-1.5	-0.8	-2.7	0.2
Osteoporosis (self-reported)	1.4	1.8	5.5	-1.3	0.9	-1.1	0.9	-1.5	1.6	0.8	1.0	2.4	1.9	-1.3
Age started oral contraceptive pill	1.4	1.7	5.2	1.2	2.3	-1.0	1.5	0.2	1.1	2.1	1.1	1.0	1.4	1.0
Alzheimer’s Disease (in mother)	1.3	1.6	4.2	-0.2	-0.7	0.7	-2.0	1.1	-2.1	-1.9	-1.3	-1.1	-1.2	0.3
Medication: Levothyroxine sodium	1.3	2.3	6.8	-0.1	-2.1	0.7	-1.9	1.1	-2.1	-2.6	-0.6	-1.1	-2.0	0.0
Impedance of arm (left)	1.3	6.1	23.4	-0.8	-1.9	0.1	-4.1	1.5	-3.2	-4.8	-2.4	-2.4	-2.1	-0.9
Glaucoma (self-reported)	1.3	1.6	3.2	0.7	-0.7	1.8	-1.7	1.5	-1.6	-1.6	-0.7	-1.1	-1.5	0.8
Medication: Ventolin 100micrograms inhaler	1.3	1.7	5.4	-0.3	1.7	-0.3	1.5	-1.3	1.5	1.2	1.4	1.3	2.3	-0.7
Number of children fathered	1.3	1.4	5.7	-1.0	0.0	-1.0	1.4	-1.3	1.0	0.9	2.4	0.9	1.4	-1.2
Medication: Omeprazole	1.3	1.6	3.5	1.6	1.6	1.8	-1.2	1.9	-1.0	-1.4	0.1	0.6	-0.7	1.4
Supplements: Vitamin C	1.3	1.5	7.1	-2.0	-2.7	0.6	-0.7	-0.7	-0.9	-1.4	-0.5	-0.4	-0.8	-1.3
Illnesses of father: Heart disease	1.3	1.8	3.6	0.8	-1.3	0.1	-1.8	1.5	-1.6	-1.6	-1.9	-1.3	-1.7	0.7
Guilty feelings	1.3	2.0	6.2	-0.2	1.4	-1.5	1.6	-0.9	1.9	1.8	0.9	2.5	1.4	-0.3
Cholesterol lowering medication	1.3	2.0	5.3	2.3	-1.0	0.7	-1.2	1.7	-1.6	-0.4	-0.7	-2.0	-1.7	1.5
Alcohol drinker status: Previous	1.3	1.5	2.9	0.1	1.7	-1.2	1.3	-1.5	1.5	1.2	1.2	1.2	1.7	-0.6
Heel T-Score	1.2	9.9	24.7	2.0	2.2	-0.2	5.0	-2.5	4.1	4.8	2.9	4.4	3.4	-0.7
Type 2 Diabetes (T2D) (2018)	1.2	2.2	8.0	2.5	1.5	2.8	-0.5	1.8	-1.0	-1.4	0.3	0.2	-1.2	1.4
Had menopause	1.2	1.5	4.0	0.7	-1.5	1.2	-0.9	1.2	-1.3	-0.2	-1.4	-1.6	-2.0	1.2
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	4.2	0.1	1.6	-1.1	1.5	-1.4	1.5	2.0	1.0	1.0	1.2	-0.4
Medication: Cholesterol lowering	1.2	1.9	4.7	1.4	-0.4	1.9	-1.6	1.0	-1.7	-2.2	-1.1	-1.6	-1.6	0.3
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	6.4	-2.3	-1.3	-0.4	-0.0	-1.7	0.0	-0.8	1.0	0.4	0.6	-2.5
Exposure to tobacco smoke outside home	1.2	1.6	4.2	1.1	-0.4	1.3	-1.0	1.6	-1.1	-1.0	-1.4	-1.4	-2.0	1.4
Loneliness, isolation	1.2	1.6	5.5	2.3	0.9	1.7	-0.3	1.6	-0.1	0.2	-1.3	0.3	-0.9	2.3
Mineral and other dietary supplements	1.2	1.6	3.9	1.0	1.6	-2.0	1.5	-0.5	1.5	1.8	1.5	0.9	1.0	0.2
Commuting to job workplace: Public transport	1.2	1.5	3.4	0.4	1.4	-1.1	1.6	-1.3	1.8	1.0	0.5	1.3	1.9	-0.5
Body Mass Index (BMI) (2010)	1.1	1.5	5.5	-1.2	-0.9	-0.0	-1.8	0.1	-1.4	-2.3	-1.0	-1.3	-1.0	-1.1
Schizophrenia (2014)	1.1	2.3	8.4	-0.2	0.4	-0.6	2.3	-1.8	1.8	2.9	1.5	1.3	1.7	-0.4
Sitting height	1.1	8.2	38.1	-2.9	-0.3	-6.2	1.9	-3.8	3.0	1.7	-0.7	2.1	2.2	-3.4
Hair/balding pattern: Pattern 2	1.1	1.4	5.5	-1.9	-2.3	1.1	-1.2	-0.7	-0.8	-1.3	-0.7	-0.5	-0.4	-1.4
Illnesses of siblings	1.1	1.6	6.1	-1.6	-0.2	-2.5	-0.1	-1.6	0.6	0.7	0.1	0.3	1.5	-2.1
Arm fat percentage (right)	1.1	4.2	19.6	-1.7	-1.4	1.8	-3.3	1.1	-2.1	-4.4	-1.3	-0.1	-2.1	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	4.8	2.2	-0.3	-0.0	-1.7	1.4	-1.6	-0.4	-1.6	-0.8	-1.2	1.9
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.0	1.1	1.7	1.4	1.6	0.3	1.0	0.8	0.9	1.3	1.0	1.1
Medication: Ibuprofen	1.1	1.3	4.5	-1.8	-2.1	-0.4	-1.1	-0.4	-1.0	-1.1	0.1	-0.8	-0.5	-1.7
Leg fat-free mass (right)	1.1	6.0	10.9	-2.9	-0.6	-3.3	2.2	-3.3	3.0	2.7	0.8	3.2	1.9	-2.5
Leg predicted mass (right)	1.1	6.1	11.0	-2.9	-0.6	-3.3	2.2	-3.3	3.0	2.7	0.8	3.2	1.9	-2.5
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.1	-1.5	-1.5	1.8	-1.4	-0.1	-1.2	-1.7	-1.4	-0.5	-0.9	-0.7
High cholesterol (Self-reported)	1.1	2.0	4.8	2.2	-1.0	0.9	-1.5	1.3	-1.9	-1.3	-0.1	-2.1	-1.7	0.9
Rheumatoid Arthritis	1.0	1.4	3.8	1.2	-0.3	1.1	-1.2	2.0	-0.8	-0.5	-0.8	-0.1	-1.7	1.9
Other serious medical condition/disability diagnosed by doctor	1.0	1.4	5.2	-1.2	0.7	-2.3	0.5	-1.7	0.8	0.1	0.7	0.5	1.6	-1.5
Hand grip strength (right)	1.0	2.7	11.5	-0.4	0.2	-2.4	2.1	-1.5	2.3	3.4	0.4	1.3	1.0	-0.4
Townsend deprivation index at recruitment	1.0	1.4	6.1	2.5	1.4	0.8	-0.9	1.8	-1.1	-0.9	-0.9	-0.1	-0.5	1.3
Chronic bronchitis/emphysema (father)	1.0	1.2	5.1	1.1	2.3	-1.3	0.6	-0.2	1.2	1.0	1.1	0.9	1.3	0.4
Happiness	1.0	1.2	5.7	0.2	1.4	-0.4	1.5	-0.5	1.5	2.4	0.0	1.2	0.6	0.8
Prospective memory result	1.0	1.2	5.2	-1.1	-1.2	0.4	-0.9	-1.1	-0.7	-2.3	0.8	-0.6	-0.3	-1.8
Loud music exposure frequency	1.0	1.1	2.9	0.5	-0.2	0.9	-1.5	0.8	-1.7	-1.6	-1.2	-0.7	-1.2	0.1
Wheeze or whistling in the chest in last year	1.0	1.9	4.2	1.9	2.0	1.6	1.4	1.1	0.9	1.4	0.9	1.2	0.3	1.9
Comparative height size at age 10	1.0	5.3	20.4	-0.6	-3.7	-0.0	-2.2	1.3	-2.1	-1.4	-4.5	-2.0	-3.4	0.6
Age at last live birth	1.0	1.5	3.9	-2.0	-0.0	-1.6	0.6	-1.6	0.9	-0.0	1.2	1.1	1.2	-2.0
Arm fat percentage (left)	1.0	4.0	18.7	-1.7	-1.3	1.8	-3.1	1.1	-2.0	-4.3	-1.1	-0.1	-2.0	-1.0
Osteoarthritis (self-reported)	1.0	1.3	3.8	1.6	0.9	1.0	-0.7	1.9	-1.1	-0.4	-0.7	-1.0	-0.7	1.9
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	4.0	1.0	0.7	1.2	-1.5	1.6	-1.3	-2.0	-0.2	0.1	-0.9	0.7
Type 2 Diabetes (T2D) (2012)	0.9	1.0	4.6	1.1	2.1	0.7	0.9	0.3	0.7	0.5	0.6	1.6	0.8	0.0
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.8	-0.4	-0.4	1.3	-0.8	-0.3	-1.0	-2.2	-0.5	-1.1	-1.0	-0.8
Trunk fat mass	0.9	4.0	16.0	-2.3	-1.6	0.7	-3.1	0.6	-1.8	-4.0	-2.1	0.1	-2.0	-1.5
Medication: Amlodipine	0.9	1.2	2.6	1.3	0.4	0.8	-1.3	1.6	-1.1	-0.2	-1.1	-1.4	-1.2	1.5
Birth weight	0.9	2.0	4.9	-0.1	2.2	-1.8	1.8	-1.3	2.1	1.4	1.1	1.3	1.5	-0.5
High blood pressure (siblings)	0.9	1.3	4.8	1.8	0.7	1.8	0.8	1.5	0.1	0.4	0.4	0.5	-0.6	2.2
Comparative body size at age 10	0.9	2.4	4.5	-0.7	-1.9	2.1	-1.4	0.1	-1.6	-1.7	-2.0	-2.0	-2.1	-0.2
Knee pain experienced in last month	0.9	1.4	3.5	0.4	-0.1	1.1	-1.8	1.7	-1.9	-1.8	-0.6	0.5	-1.0	1.0
Ever had bowel cancer screening	0.9	1.1	3.5	-1.3	-0.1	-1.7	-0.0	-1.7	0.5	-0.4	0.7	0.5	1.0	-1.9
Smoking status: Current	0.9	1.4	5.9	2.4	1.4	0.9	0.9	1.3	0.6	0.8	-0.6	0.5	-0.2	1.9
Bipolar Disorder (2018)	0.8	1.2	3.2	0.1	1.0	-0.8	1.3	-1.3	1.4	1.8	1.0	1.2	1.4	-0.4
Fasting Glucose	0.8	1.0	2.5	-0.1	0.5	-0.3	0.8	-1.2	1.0	1.0	1.4	1.4	1.6	-0.9
Blood White Count	0.8	5.8	18.7	-0.0	3.9	-1.9	2.4	-1.5	2.7	0.8	2.6	4.3	2.9	-1.1
Smoking Status	0.8	1.8	5.3	1.5	1.6	1.2	2.3	0.5	1.3	1.9	0.6	1.3	0.5	1.5
Allergy or Eczema	0.8	2.1	6.9	-1.7	0.6	-2.6	-1.1	-1.3	-0.2	-1.4	0.5	-1.7	0.8	-2.6
Leg fat-free mass (left)	0.8	4.1	8.2	-2.9	-1.0	-2.8	1.4	-2.6	2.3	1.9	0.2	2.9	1.2	-2.3
Medication: Atenolol	0.8	1.0	2.5	1.3	-0.3	1.0	-0.5	1.1	-0.7	-0.9	-0.4	-1.6	-1.4	1.1
Leg predicted mass (left)	0.8	4.1	8.1	-2.9	-1.1	-2.8	1.4	-2.6	2.3	1.9	0.1	2.8	1.1	-2.3
Diabetes (self-reported)	0.8	1.3	4.8	1.7	0.7	2.2	-0.6	1.2	-1.1	-1.6	0.3	0.0	-1.1	0.3
Hip circumference	0.8	3.6	17.7	-4.2	-1.0	-0.9	-1.1	-1.7	0.2	-2.0	-0.1	2.1	0.5	-3.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	3.4	-1.8	-1.8	-0.3	-0.9	-0.2	-1.1	-0.8	-0.3	-0.7	-0.5	-1.6
Hair/balding pattern: Pattern 4	0.8	1.8	8.0	2.8	0.6	0.0	0.7	1.5	0.5	1.8	-0.3	-0.7	-1.0	2.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	4.1	0.3	1.1	-0.9	1.5	-0.9	0.8	0.9	2.0	0.5	0.6	-0.4
Shortness of breath walking on level ground	0.8	0.9	3.0	1.3	0.6	1.7	-0.2	1.4	-0.2	-0.0	-0.5	-0.4	-1.0	1.6
Whole body fat mass	0.8	3.3	13.1	-1.9	-1.4	1.2	-2.8	0.8	-1.6	-3.6	-1.9	0.2	-2.0	-1.1
Overall health rating	0.8	1.8	4.9	1.2	-0.5	2.2	-1.0	1.9	-0.9	-0.7	-0.4	-1.1	-1.7	2.1
Whole body fat-free mass	0.8	4.3	9.0	-2.3	-0.9	-3.0	1.9	-2.6	2.6	2.8	-0.1	2.6	1.1	-1.8
Whole body water mass	0.8	4.3	8.8	-2.3	-0.8	-3.0	2.0	-2.7	2.6	2.7	-0.0	2.7	1.1	-1.8
Leg fat percentage (left)	0.8	3.1	14.3	-0.6	-0.4	2.4	-2.5	1.6	-1.8	-3.8	-0.9	-0.4	-1.9	-0.2
Hypothyroidism (self reported)	0.7	1.6	4.3	0.2	-2.1	1.1	-2.0	0.9	-1.6	-1.9	0.0	-0.7	-1.6	0.0
Lung FEV1/FVC ratio	0.7	3.3	12.7	-0.9	-1.6	0.7	-2.4	1.2	-2.4	-3.6	0.4	-2.4	-1.8	-1.1
Current tobacco smoking	0.7	1.2	5.6	2.4	1.0	0.9	0.5	1.5	0.2	0.4	-0.8	0.2	-0.4	1.8
Supplements: Glucosamine	0.7	1.0	2.4	-0.8	-0.9	1.1	-1.2	1.0	-1.4	-1.6	-0.9	-0.9	-0.7	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	4.1	0.7	1.2	-0.5	0.7	-0.5	1.2	2.0	0.8	1.2	1.1	0.7
Trunk fat-free mass	0.7	3.8	10.4	-1.6	-0.8	-3.0	2.1	-2.3	2.6	3.2	-0.4	2.3	0.9	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.7	1.3	-0.2	0.5	-0.9	1.1	-0.8	-0.3	-1.3	-0.4	-1.1	1.2
Trunk predicted mass	0.7	3.8	10.6	-1.5	-0.8	-3.0	2.1	-2.2	2.6	3.3	-0.4	2.2	0.8	-1.1
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.0	-0.2	0.6	-1.3	1.3	-0.8	1.3	1.7	1.0	1.6	1.6	-0.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	4.6	0.2	-1.0	1.1	-1.8	0.9	-1.6	-2.1	0.2	-0.5	-1.2	0.2
Qualifications: College or University degree	0.7	2.1	10.7	0.7	0.7	-1.3	1.9	-1.0	1.6	3.3	0.9	1.0	1.6	0.1
Medication for pain relief, constipation, heartburn	0.7	1.2	3.0	-0.5	1.0	-1.0	1.4	-1.2	1.7	0.8	0.7	1.5	1.6	-0.6
Leg fat mass (right)	0.7	2.8	10.0	-1.2	-1.2	1.6	-2.6	1.3	-1.6	-3.2	-1.6	0.1	-2.0	-0.4
Average weekly red wine intake	0.7	1.0	2.8	0.5	1.0	-1.7	1.4	-0.5	0.9	0.9	1.6	0.6	0.8	-0.3
Diabetes diagnosed by doctor	0.7	1.2	5.4	1.2	0.8	2.1	-0.5	0.7	-1.0	-2.3	0.3	0.5	-0.9	-0.4
Medication: Lisinopril	0.7	0.9	2.4	1.1	0.5	0.2	1.4	0.2	1.4	1.5	1.1	1.0	0.5	0.9
Risk taking	0.7	1.0	2.5	0.9	1.2	-0.8	1.4	-1.1	1.6	1.3	0.7	0.9	0.5	-0.2
Number of treatments/medications taken	0.6	1.1	1.9	1.0	0.0	1.2	-1.3	1.4	-1.3	-0.5	-0.3	-1.2	-1.2	1.4
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.0	1.1	-0.8	1.1	-0.7	0.8	-0.7	0.3	-1.7	-0.3	-0.7	1.2
Medication: Metformin	0.6	0.9	3.1	1.6	0.2	1.8	-0.0	1.3	-0.6	-0.9	0.0	0.8	-1.1	0.7
Severe depression (siblings)	0.6	0.7	2.8	-0.8	-0.4	-0.8	0.3	-1.7	0.7	-0.1	0.3	0.4	0.7	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	4.4	2.1	-0.1	1.2	-0.8	1.2	-1.3	-0.6	-0.7	-1.1	-1.5	1.0
Hayfever, allergic rhinitis or eczema	0.6	1.4	5.4	-1.2	0.8	-2.3	-0.1	-1.3	0.5	-0.4	0.9	-0.9	1.0	-2.0
Hearing difficulty/problems with background noise	0.6	1.0	4.8	0.7	2.2	1.2	0.3	1.2	-0.1	-0.1	-0.1	1.4	0.3	1.2
Qualifications: None of the above	0.6	1.2	5.1	1.5	0.5	1.6	0.6	1.5	-0.2	0.5	-0.1	-0.5	-0.8	2.3
Financial difficulties in last 2 years	0.6	0.8	2.5	1.0	1.1	-0.8	0.7	-0.0	1.1	1.1	0.4	1.6	0.6	0.6
Breastfed as a baby	0.6	0.8	1.8	-0.3	0.7	-1.4	0.4	-0.5	0.6	1.2	1.2	1.2	1.3	-0.3
Blood clot in the leg (DVT)	0.6	0.8	3.5	0.7	0.7	-1.9	0.7	-0.4	0.7	1.1	1.0	0.8	1.0	-0.3
Number of full brothers	0.6	0.8	2.6	-0.0	-0.7	1.4	-1.6	0.7	-1.1	-1.2	-0.7	-0.7	-0.7	-0.1
Neck or shoulder pain in last month	0.6	0.9	1.9	1.0	1.2	0.4	1.3	0.1	0.9	1.4	1.1	1.4	0.5	0.8
Migraine (self-reported)	0.6	0.7	2.5	-0.8	-1.2	-1.6	-0.1	-0.8	-0.3	1.3	-0.8	-1.0	0.1	0.1
Asthma (self-reported)	0.6	1.1	4.2	-0.8	2.0	-0.2	0.3	-0.8	0.9	0.4	1.2	1.5	1.7	-0.7
Number of self-reported non-cancer illnesses	0.6	1.1	2.5	1.0	-0.0	0.8	-1.5	1.3	-1.6	-0.9	-0.2	-1.3	-1.0	1.1
Eye problems/disorders: Glaucoma	0.6	0.7	2.2	0.6	-0.6	1.5	-0.8	1.1	-0.9	-0.6	0.1	-0.8	-0.8	0.9
Basal metabolic rate	0.6	3.0	6.2	-2.4	-0.9	-2.5	1.3	-2.2	2.1	1.9	-0.3	2.4	0.7	-1.8
Fractured/broken bones in last 5 years	0.6	0.7	3.2	-1.8	-1.0	-0.6	-0.6	-1.0	-0.2	-0.7	0.5	-0.2	0.0	-1.4
Ever depressed for a whole week	0.6	0.8	2.3	0.0	1.0	-0.4	0.6	-1.0	0.9	0.8	0.9	1.5	1.4	-0.7
Pain experienced in last month	0.6	1.0	2.8	-0.9	-1.2	-0.6	-0.7	-0.8	-0.2	-1.7	-0.7	-1.4	-0.5	-1.6
Supplements: Calcium	0.6	0.7	2.3	-0.4	-0.8	0.2	-1.2	0.3	-1.1	-1.5	-1.2	-0.5	-0.4	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	5.1	0.0	0.3	-0.2	1.6	-1.3	1.3	2.3	0.9	1.3	1.2	-0.4
BMI	0.5	3.1	9.2	-2.6	-1.8	2.0	-2.0	0.3	-1.6	-3.0	-0.8	-0.0	-1.9	-1.7
Height	0.5	9.8	53.0	-2.2	-1.5	-7.3	1.4	-3.4	3.2	3.2	-3.1	2.6	1.5	-2.1
Relative age of first facial hair	0.5	0.9	6.9	-0.3	1.2	-2.6	-0.5	-0.4	0.2	-0.5	1.1	0.1	0.5	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.6	1.2	0.9	1.2	-0.5	0.8	-0.3	-0.4	-0.6	0.5	-0.0	1.3
Worrier / anxious feelings	0.5	0.9	2.7	-1.5	-1.4	-1.5	-0.4	-1.1	-0.1	-0.4	0.8	0.3	0.3	-1.6
Number of live births	0.5	0.7	2.9	-1.6	-0.5	-0.5	-0.1	-1.3	-0.1	-0.6	0.8	-0.1	0.0	-1.7
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.2	1.0	1.8	-0.0	1.1	-0.2	1.3	1.6	-0.3	1.3	1.1	0.7
Asthma	0.5	1.0	2.8	-0.9	1.7	-0.2	0.4	-0.8	0.9	0.6	1.1	1.5	1.6	-0.6
Pulse wave Arterial Stiffness index	0.5	0.5	1.4	-0.2	0.2	0.4	1.1	-0.5	0.9	1.0	1.1	1.2	0.6	-0.1
Arm fat mass (right)	0.5	1.9	7.6	-2.0	-1.3	0.7	-2.0	0.3	-0.9	-2.8	-1.0	0.9	-1.3	-1.2
Pulse wave reflection index	0.5	0.6	1.6	1.1	-0.0	1.0	0.3	1.1	0.1	0.9	-0.1	0.4	-0.9	1.3
Headache pain in last month	0.5	0.9	5.4	0.2	1.1	-0.8	1.2	-0.4	0.7	2.3	0.3	0.1	0.8	0.9
Eye problems/disorders: None of the above	0.5	0.5	1.8	0.1	0.6	-1.2	1.2	-0.2	0.7	1.3	0.6	0.3	0.7	0.0
Medication: Allopurinol	0.5	0.7	2.1	0.8	-0.1	1.4	-0.4	1.2	-0.6	-1.0	-0.5	-0.7	-1.0	1.1
Heart disease (mother)	0.5	0.7	2.5	1.1	0.4	1.6	0.4	0.7	-0.2	-0.1	-0.9	-0.0	-1.0	1.2
Arm predicted mass (right)	0.5	2.7	6.8	-1.6	-0.4	-2.2	1.9	-2.0	2.2	2.6	-0.2	2.0	0.7	-1.0
Had major operations	0.5	0.6	2.0	-1.4	-0.5	-0.6	-0.4	-0.8	0.1	-0.3	-1.4	0.3	-0.3	-1.0
Family relationship satisfaction	0.5	0.7	2.8	0.9	0.7	0.1	1.2	-0.2	1.2	1.7	-0.4	0.5	-0.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	6.5	-1.2	-1.0	-2.5	-0.2	-1.1	0.5	0.2	-0.7	-0.5	-0.1	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.8	-0.5	-1.7	0.9	-0.6	0.4	-1.0	-1.0	-0.3	-0.8	-0.6	0.1
Arm fat mass (left)	0.5	1.9	7.5	-2.0	-1.2	0.8	-1.9	0.3	-0.9	-2.7	-1.0	0.8	-1.4	-1.2
Alcohol drinker status: Never	0.5	0.6	3.0	-1.0	-1.7	-0.3	0.6	-1.0	0.1	0.7	0.7	-0.6	0.0	-0.9
Arm fat-free mass (left)	0.5	2.3	5.1	-1.5	-0.4	-2.0	1.6	-1.8	2.1	2.2	-0.1	2.1	0.6	-1.1
Diastolic blood pressure, automated reading	0.5	1.5	3.7	-0.8	0.4	-1.2	1.9	-1.2	1.7	1.9	1.5	0.6	1.3	-0.3
Myopia	0.5	0.8	4.4	1.2	0.5	0.2	0.9	0.2	0.7	2.1	-0.1	0.5	0.2	1.2
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	3.8	0.4	0.4	-1.9	0.4	-0.4	0.4	0.9	1.0	0.6	1.0	-0.5
Pack years of smoking	0.5	0.7	2.6	0.1	1.6	-0.8	0.8	-0.4	0.8	0.7	-0.3	1.4	1.1	-0.3
Leg fat mass (left)	0.5	1.8	7.3	-1.4	-0.9	1.1	-2.1	0.7	-1.1	-2.7	-1.1	0.5	-1.4	-0.7
Depression (Nagel 2018)	0.4	0.6	1.4	0.9	0.1	1.1	0.6	-0.3	0.6	1.1	-0.3	1.0	0.7	1.2
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.1	0.5	-0.2	-0.3	-1.2	1.1	-1.4	-1.5	-1.8	-1.6	-1.1	0.6
Major Depression (MDD)	0.4	0.5	2.1	0.3	0.9	0.5	0.7	-0.2	1.5	0.5	0.9	0.4	0.7	0.3
HbA1C	0.4	0.4	1.3	0.4	0.3	1.0	0.4	0.5	0.5	1.1	0.6	0.8	0.1	1.0
LDL Cholesterol	0.4	0.6	2.3	1.1	0.5	1.5	1.0	0.5	0.1	0.9	0.9	-0.3	0.3	0.8
Respiratory disease	0.4	0.9	2.5	-1.3	1.6	-0.5	0.1	-1.1	0.7	0.3	0.8	0.7	1.5	-1.1
Average weekly spirits intake	0.4	0.4	1.0	-0.3	0.1	-1.0	0.9	-0.4	0.7	0.9	0.8	0.8	0.6	-0.4
Sensitivity / hurt feelings	0.4	0.7	2.2	0.3	-1.5	0.8	-0.5	0.5	-0.7	-0.8	-1.2	-0.8	-1.4	0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.4	-1.3	-0.4	0.1	-0.8	-0.1	-0.7	-1.6	0.1	-0.2	-0.3	-0.6
Allergy	0.4	1.0	3.0	1.3	-0.8	1.7	0.1	1.0	-0.3	0.2	-1.1	0.4	-0.9	1.6
Falls in the last year	0.4	0.6	5.2	0.6	0.5	-2.3	-0.3	-0.0	-0.4	-0.5	0.1	0.2	0.1	-0.6
Depression (self-reported)	0.4	0.5	1.8	1.3	0.9	-0.8	0.1	-0.1	0.4	0.9	-0.6	0.7	0.7	0.7
Standing height	0.4	4.4	22.5	-2.6	-1.5	-4.7	0.4	-2.2	1.5	1.3	-2.4	1.4	0.4	-2.1
Exposure to tobacco smoke at home	0.4	0.4	1.7	0.3	0.8	-0.7	0.4	-0.5	0.7	1.0	0.1	1.3	0.7	-0.2
Number of full sisters	0.4	0.5	1.7	-1.1	0.6	-0.8	-0.1	-0.7	0.1	-1.2	0.7	0.2	0.3	-1.3
Long-standing illness, disability or infirmity	0.4	0.7	2.5	0.2	-0.2	0.3	-1.6	0.9	-1.1	-1.4	-0.4	-0.6	-0.7	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.0	0.0	-0.4	-1.4	-0.3	-0.0	-0.5	-0.7	-0.1	-1.4	-0.5	-0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	-1.5	-0.1	-0.2	0.4	-0.9	0.1	-0.1	0.5	0.3	0.5	-1.3
Miserableness	0.4	0.7	2.7	-0.1	-0.2	1.6	-0.8	0.8	-0.9	-0.7	-1.2	-0.8	-1.1	0.6
Wears glasses or contact lenses	0.4	0.4	1.7	-0.1	-0.1	-1.3	-0.8	0.3	-0.8	-0.8	-1.0	-0.8	-0.4	-0.0
Financial situation satisfaction	0.4	0.5	1.8	-0.8	0.7	0.4	1.1	0.0	1.2	0.7	0.3	1.3	0.2	-0.1
Medication: Bendroflumethiazide	0.4	0.6	2.3	0.1	-0.3	-0.4	-0.5	0.6	-0.8	-1.0	-0.2	-1.5	-1.4	0.4
Commuting to job workplace: Cycle	0.4	0.5	1.1	1.1	0.6	0.7	-0.1	1.1	-0.5	0.9	0.1	0.2	-0.4	1.0
Alzheimer’s Disease (including proxy)	0.3	0.4	1.5	-0.6	-0.2	0.6	-0.8	0.2	-1.1	-1.2	0.0	-0.5	-0.3	-0.1
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.4	1.0	0.6	0.7	-0.4	0.9	-0.6	-0.6	-1.1	-1.2	-0.9	0.9
HDL Cholesterol	0.3	0.4	1.4	-0.2	-0.1	-0.1	-0.6	0.8	-1.1	-0.8	-0.1	-0.8	-1.2	0.5
Ever had hysterectomy (womb removed)	0.3	0.3	1.3	-0.0	-0.0	-1.1	0.8	-0.4	0.5	1.0	0.9	-0.4	0.1	-0.1
Supplements: Zinc	0.3	0.4	0.9	-0.6	-1.0	0.6	0.5	-0.8	0.5	0.3	-0.0	0.9	0.6	-0.6
Medication: Co-codamol	0.3	0.3	2.0	0.5	1.4	0.0	-0.1	0.5	0.1	-0.1	0.9	-0.7	0.3	0.3
Diabetes (father)	0.3	0.4	1.1	-0.5	0.1	0.7	0.3	-0.6	0.6	0.2	1.1	0.9	0.4	-0.7
Fed-up feelings	0.3	0.6	2.3	0.9	0.6	0.6	-0.0	1.0	-0.2	0.6	-1.1	-0.4	-0.6	1.5
Relative age voice broke	0.3	0.5	1.0	0.5	0.6	-0.9	-1.0	1.0	-0.6	-1.0	0.4	-0.9	-0.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	2.1	-0.1	-0.7	-1.4	0.2	-0.1	0.4	0.8	-0.6	-0.6	-0.2	0.1
Waist circumference	0.3	1.1	4.3	-0.5	0.1	1.9	-1.4	0.8	-0.6	-2.1	-0.8	0.7	-1.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	4.2	2.0	0.9	0.6	0.3	0.5	0.1	0.8	0.2	1.1	0.2	0.8
Pain all over the body in last month	0.3	0.4	1.0	0.6	-0.2	-0.4	-1.0	0.8	-0.9	-0.2	0.3	-1.0	-0.5	0.4
Weight	0.3	1.3	5.8	-2.4	-1.0	-0.8	-0.6	-0.8	0.5	-0.7	-1.1	1.5	-0.5	-1.5
Hair/balding pattern: Pattern 3	0.3	0.4	1.3	0.0	0.3	-0.3	0.7	-1.1	0.5	0.6	1.0	-0.1	0.9	-0.8
Tense / ‘highly strung’	0.3	0.6	1.6	0.8	0.7	-0.8	1.0	-0.2	0.9	1.3	0.7	0.9	0.7	0.2
Gout (self-reported)	0.3	0.3	1.7	0.7	0.2	1.3	0.2	0.6	0.2	-0.7	0.1	-0.4	-0.4	0.9
Arm fat-free mass (right)	0.3	1.7	5.3	-1.2	-0.6	-1.5	1.5	-1.4	1.8	2.3	-0.5	1.6	0.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.8	0.9	0.2	-0.8	0.2	-0.2	0.0	0.9	-0.8	0.5	0.8	0.3
Age at first live birth	0.3	0.5	1.8	-1.3	-0.1	-0.9	0.3	-0.7	0.6	0.1	0.5	0.6	0.9	-0.8
Pulse wave peak to peak time	0.3	0.4	1.2	0.1	-0.2	-0.8	-0.9	0.2	-0.6	-0.8	-1.1	-1.0	-0.5	-0.0
Health satisfaction	0.3	0.4	2.0	-1.4	-0.9	1.1	-0.6	-0.1	-0.3	-0.5	0.2	-0.0	-0.2	-0.3
Emphysema/chronic bronchitis	0.3	0.4	1.4	0.5	0.6	0.0	1.2	0.1	0.8	0.8	0.6	0.3	0.4	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.1	0.2	0.9	0.2	-0.5	0.1	-0.7	-1.4	0.5	-0.1	-0.4	-0.4
Illnesses of siblings: Diabetes	0.3	0.4	1.0	0.4	-0.6	-0.1	-0.6	1.0	-0.6	-1.0	0.1	0.0	-1.0	0.8
Eye problems/disorders: Cataract	0.3	0.4	1.1	0.4	-0.4	0.8	-1.1	0.4	-0.6	-0.9	-0.9	0.1	-0.2	0.2
Breast cancer (self-reported)	0.3	0.3	1.1	-1.1	-0.2	-0.1	-1.0	0.4	-0.4	-0.9	0.3	0.0	-0.2	-0.7
Medication: Gliclazide	0.3	0.4	1.5	-0.3	0.7	-0.6	-0.1	-0.3	-0.3	-1.2	0.7	0.4	-0.1	-1.0
Average weekly beer plus cider intake	0.3	0.5	2.4	-0.4	-1.6	0.2	-0.5	0.3	-0.5	-0.8	-0.7	-1.0	-0.7	-0.1
Arm predicted mass (left)	0.3	1.6	3.6	-1.4	-0.9	-1.7	1.2	-1.4	1.7	1.9	-0.5	1.7	0.2	-0.9
Depressed Affect (Nagel 2018)	0.2	0.5	2.0	0.7	0.1	1.1	0.1	0.5	0.1	0.6	-0.9	-0.5	-0.7	1.4
Schizophrenia (2018)	0.2	0.4	2.1	-0.0	-0.4	0.4	0.9	-0.7	0.6	1.5	0.4	0.7	0.4	-0.1
Reaction Time	0.2	0.4	1.8	0.2	1.4	0.0	0.7	-0.9	0.5	0.2	0.6	-0.4	0.1	-0.5
Age at First Birth	0.2	0.2	0.8	-0.5	-0.0	-0.9	-0.2	-0.9	0.2	0.3	0.4	-0.3	0.8	-0.4
Lupus	0.2	0.3	0.7	-0.6	0.1	0.8	0.3	-0.7	0.3	0.7	0.8	0.7	0.8	-0.1
Neuroticism (2016)	0.2	0.3	1.1	-0.5	-0.5	-0.3	0.1	-0.8	0.6	0.2	-0.0	0.8	0.9	-1.1
Hair Pigment	0.2	4.4	9.4	1.9	3.1	-0.1	2.9	0.4	2.7	3.1	1.5	1.8	2.4	1.8
Medication for hormone replacement therapy	0.2	0.2	0.8	-0.3	-0.0	0.1	0.6	-0.9	0.5	0.4	0.3	-0.5	0.4	-0.4
Pack years adult smoking proportion	0.2	0.3	1.5	0.3	1.2	-0.6	0.4	-0.0	0.5	0.3	-0.5	0.9	0.7	-0.1
Maternal smoking around birth	0.2	0.3	1.1	-0.5	0.2	-0.6	0.7	-0.7	0.6	0.7	1.0	0.1	0.5	-0.4
Taking other prescription medications	0.2	0.4	0.8	0.9	0.9	0.4	-0.8	0.7	-0.7	-0.5	0.7	0.0	-0.3	0.6
Body mass index (BMI)	0.2	0.7	2.0	-1.4	-0.4	1.3	-0.7	0.1	-0.2	-1.4	-0.0	0.9	-0.7	-0.6
Past tobacco smoking	0.2	0.3	1.2	0.0	-0.8	-0.1	-1.1	0.4	-0.7	-0.5	-0.6	-0.7	-0.3	0.2
Nervous feelings	0.2	0.4	1.7	1.3	0.9	0.1	0.3	0.6	0.1	0.5	1.2	0.4	0.5	0.5
Mouth/teeth dental problems	0.2	0.2	0.9	-0.8	0.1	-0.7	-0.9	0.0	-0.4	-0.7	-0.4	0.1	0.0	-0.5
Medication: Simvastatin	0.2	0.2	1.5	0.9	0.4	1.2	-0.1	-0.0	-0.1	-0.3	0.4	-0.2	-0.1	-0.2
Father’s age at death	0.2	0.3	0.9	0.5	-0.5	0.4	0.3	-0.5	0.5	0.9	0.8	-0.2	0.5	0.2
Length of working week for main job	0.2	0.2	0.9	0.6	0.2	1.0	0.5	0.5	0.2	-0.5	0.7	-0.2	-0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.7	-0.8	0.2	-0.4	0.0	-1.0	0.3	-0.1	-0.2	0.6	0.8	-1.3
Alcohol intake frequency.	0.2	0.4	1.8	-0.1	-0.6	0.6	-1.4	-0.1	-0.9	-0.8	-0.6	-0.4	-0.1	-0.5
Chest pain or discomfort	0.2	0.2	1.5	0.1	-0.0	1.2	-0.2	0.3	-0.4	-0.7	0.1	-0.3	-0.4	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.4	0.0	1.2	0.2	-0.6	0.4	0.3	-0.8	-0.2	0.8	-0.0	0.1
Friendships satisfaction	0.2	0.2	1.0	0.1	0.4	-0.5	-0.1	-0.1	0.4	1.0	-0.8	-0.2	-0.3	0.4
Hearing aid user	0.2	0.2	0.7	0.8	0.1	0.1	-0.6	0.7	-0.6	-0.8	-0.4	0.4	0.1	0.1
Mother’s age at death	0.2	0.2	0.8	0.2	-0.9	0.9	0.5	-0.3	-0.0	0.4	-0.2	0.0	-0.4	0.4
Illnesses of father: High blood pressure	0.2	0.3	0.8	0.3	-0.2	0.1	0.8	-0.7	0.9	0.4	0.9	0.1	-0.3	0.0
Unable to work because of sickness or disability	0.2	0.2	1.5	1.2	0.2	-0.1	-0.1	0.3	-0.3	-0.4	0.6	-0.5	-0.0	0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.7	0.5	-0.4	0.8	-0.0	0.2	0.2	0.6	-0.0	-0.4	-0.7	0.7
Schizophrenia vs Biploar Disorder	0.1	0.2	0.7	0.2	-0.8	0.1	0.3	0.3	-0.1	0.4	-0.5	-0.5	-0.4	0.5
Worry (Nagel 2018)	0.1	0.2	1.1	-0.0	-0.6	0.2	-0.1	-0.4	0.4	0.2	1.0	0.3	0.2	-0.3
Alzheimer’s Disease (in father)	0.1	0.1	0.5	0.0	0.3	-0.3	0.3	-0.4	0.7	0.4	0.6	-0.2	0.5	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.7	0.2	-0.3	-0.1	0.4	-0.3	0.4	0.8	-0.4	0.2	0.1	0.0
Triglycerides	0.1	0.2	0.8	0.1	-0.3	0.9	-0.6	0.1	-0.2	-0.6	-0.1	-0.8	-0.6	-0.0
Blood Red Count	0.1	1.1	3.2	-1.5	-0.2	-1.8	-1.4	0.6	-1.0	-1.5	-0.7	-0.9	-0.9	-0.7
Neuroticism	0.1	0.3	1.9	0.4	-0.3	1.4	0.4	0.2	0.4	0.6	0.4	0.6	-0.3	0.6
Number of incorrect matches in round	0.1	0.1	0.5	0.3	0.3	0.7	0.0	0.1	-0.3	-0.3	0.2	0.4	0.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	0.0	0.9	-0.3	-0.2	-0.0	-0.1	-0.8	0.2	-0.0	0.2	-0.4
Fluid intelligence score	0.1	0.2	0.9	0.7	1.0	-0.2	0.6	0.0	0.4	0.3	-0.8	-0.2	0.1	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	-0.6	-0.3	0.3	-0.4	0.5	-0.4	0.6	-0.3	0.1	-0.3	0.7
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.6	-0.2	-0.4	0.2	0.2	-0.1	0.0	0.2	-0.1	-0.5	-0.7	0.1
Medication: Paracetamol	0.1	0.2	1.3	-1.1	0.1	-0.2	0.0	-0.4	0.1	0.9	0.6	0.2	0.3	-0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.4	0.6	0.2	0.3	-0.1	-0.2	0.2	0.2	0.4	0.4	0.4	0.2
Medication: Seretide 50 evohaler	0.1	0.2	0.5	-0.2	0.2	0.7	-0.5	0.3	-0.5	-0.5	-0.6	-0.2	0.5	0.1
Mean time to correctly identify matches	0.1	0.2	1.2	0.2	1.1	0.4	0.4	-0.7	0.4	-0.2	0.1	-0.2	0.0	-0.4
Suffer from ‘nerves’	0.1	0.1	0.7	0.0	0.1	0.2	-0.2	0.1	0.4	-0.0	0.9	0.4	0.2	0.0
Smoking status: Previous	0.1	0.1	0.4	-0.5	-0.3	0.1	0.4	-0.4	0.2	0.1	0.6	0.4	-0.0	-0.4
Mood swings	0.1	0.2	1.4	0.1	0.5	0.1	0.6	-0.5	0.5	1.2	-0.3	0.2	0.0	0.3
Qualifications: nursing, teaching	0.1	0.2	0.6	-0.4	-0.0	-0.2	-0.6	-0.6	-0.3	0.0	-0.2	0.5	0.7	-0.8
Back pain experienced in last month	0.1	0.2	0.9	-0.0	0.3	0.4	0.3	0.3	0.1	1.0	0.3	0.6	0.1	0.6
Medication: Paracetamol	0.1	0.2	0.6	-0.7	0.4	0.2	0.0	-0.0	0.1	0.8	0.8	0.4	0.6	-0.1
Ever smoked	0.1	0.2	0.6	-0.2	0.1	0.4	0.8	-0.5	0.5	0.3	0.2	0.6	0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.7	-0.2	0.1	-0.8	0.3	-0.6	0.2	0.1	-0.2	-0.1	0.2	-0.5
Neuroticism score	0.0	0.0	0.1	0.1	-0.2	-0.0	0.1	0.0	0.2	-0.0	-0.0	0.3	-0.3	0.1
Irritability	0.0	0.1	0.2	-0.4	-0.2	-0.3	0.3	-0.2	0.2	0.0	0.4	0.0	-0.3	-0.4

Hub : Genes

CTSK

Models

Trait associations