Hub : Genes

GOLPH3L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1510 0.0370 0.0e+00 0.269 0.249 0.263 0.253 0.268 9.6e-33 5.2e-30 7.1e-32 1.3e-30 1.5e-32
2 GTEx Artery Tibial 0.0445 0.0192 8.0e-05 0.042 NA 0.032 NA 0.030 3.1e-04 NA 1.4e-03 NA 1.8e-03
3 GTEx Esophagus Mucosa 0.1420 0.0540 1.6e-09 0.142 NA 0.101 NA 0.130 1.0e-09 NA 3.0e-07 NA 5.5e-09
4 GTEx Muscle Skeletal 0.0236 0.0138 7.7e-03 0.013 NA -0.002 NA -0.002 1.8e-02 NA 7.1e-01 NA 6.1e-01
5 GTEx Nerve Tibial 0.3305 0.0609 0.0e+00 0.516 NA 0.501 NA 0.503 5.2e-42 NA 3.0e-40 NA 1.6e-40
6 GTEx Prostate 0.4700 0.1250 3.7e-03 0.013 NA -0.012 NA 0.000 1.5e-01 NA 8.9e-01 NA 3.2e-01
7 GTEx Skin Not Sun Exposed Suprapubic 0.2280 0.0580 0.0e+00 0.324 NA 0.308 NA 0.310 2.4e-18 NA 2.4e-17 NA 1.6e-17
8 GTEx Skin Sun Exposed Lower leg 0.1800 0.0390 0.0e+00 0.356 NA 0.389 NA 0.374 1.3e-30 NA 4.7e-34 NA 1.7e-32
9 GTEx Testis 0.1100 0.0430 3.1e-06 0.134 NA 0.132 NA 0.137 1.6e-06 NA 1.9e-06 NA 1.2e-06
10 GTEx Whole Blood 0.0340 0.0200 7.5e-03 0.032 NA 0.022 NA 0.032 6.2e-04 NA 3.6e-03 NA 5.2e-04
11 TCGA Head and Neck Squamous Cell Carcinoma 0.1240 0.0575 1.7e-16 0.162 0.164 0.154 NA 0.160 7.4e-18 4.8e-18 5.3e-17 NA 1.4e-17
12 TCGA Lung Squamous Cell Carcinoma 0.0218 0.0163 3.7e-03 0.016 0.012 0.005 NA 0.005 5.9e-03 1.6e-02 8.1e-02 NA 8.0e-02
13 TCGA Prostate Adenocarcinoma 0.0264 0.0208 4.8e-03 0.006 0.011 0.005 NA 0.009 6.7e-02 2.2e-02 9.0e-02 NA 3.5e-02
14 TCGA Thyroid Carcinoma 0.0200 0.0150 8.4e-03 0.016 0.010 0.010 NA 0.007 1.0e-02 3.0e-02 3.1e-02 NA 6.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.8 1.3 2.2 -1.0 -1.0 1.0 -1.5 1.0 -1.0 1.0 1.4 1.5 0.9 -0.8 -1.3 -1.2 1.0
Bipolar Disorder or Schizophrenia 0.6 1.6 7.4 -0.8 -0.9 1.0 -1.3 0.9 -2.7 0.9 1.1 1.2 0.7 -0.1 -1.4 -1.7 0.7
Depressed Affect (Nagel 2018) 0.2 0.4 0.8 -0.7 -0.3 0.5 -0.6 0.8 0.8 0.7 0.2 0.4 -0.8 -0.7 -0.7 -0.9 0.7
Depression (Nagel 2018) 1.1 1.7 3.7 -1.7 -1.3 1.3 -1.1 1.3 0.0 1.4 1.0 1.2 -0.8 -1.3 -1.6 -1.9 1.4
Intelligence (Savage-Jansen 2018) 0.4 1.4 2.1 1.2 1.3 -1.1 1.2 -1.4 1.2 -1.4 -1.4 -1.1 -0.3 1.4 0.9 0.9 -1.0
Neuroticism (Nagel 2018) 0.1 0.2 0.9 -0.3 -0.1 0.3 -0.6 0.1 0.4 0.2 -0.2 0.3 0.9 0.2 -0.4 -0.7 0.2
Schizophrenia (2018) 0.4 0.8 7.2 -0.2 -0.3 0.4 -0.5 0.4 -2.7 0.4 0.3 0.3 0.1 0.5 -0.7 -1.3 0.1
Schizophrenia vs Biploar Disorder 0.2 0.3 1.1 -0.3 -0.4 0.2 0.1 0.9 0.4 0.7 0.4 -0.0 0.5 -0.2 -0.7 -1.1 0.4
Worry (Nagel 2018) 0.1 0.2 1.1 0.3 0.2 -0.1 -0.1 -0.5 0.4 -0.4 -0.4 -0.2 0.8 1.1 0.1 -0.0 -0.3
Alzheimer’s Disease (in mother) 2.9 3.4 5.0 1.7 1.9 -1.8 1.9 -1.9 1.4 -1.9 -1.8 -1.8 -1.8 1.4 2.2 2.2 -1.8
Alzheimer’s Disease (in father) 0.4 0.4 2.8 -0.3 -0.4 0.4 -0.4 0.4 -1.1 0.4 0.3 0.3 1.7 -0.3 -0.3 -0.1 0.4
Alzheimer’s Disease (including proxy) 0.5 0.8 1.8 0.6 0.5 -0.8 1.2 -0.7 0.7 -0.8 -1.0 -1.3 -0.6 0.6 1.0 1.1 -0.8
Crohns Disease (2017) 5.2 11.4 15.6 3.5 3.8 -3.6 3.3 -3.9 -0.4 -3.8 -3.9 -2.7 -1.0 3.5 4.0 3.8 -3.7
Irritable Bowel Disease (IBD) 9.0 21.4 28.1 4.8 4.7 -5.0 4.8 -5.2 0.0 -5.1 -5.3 -4.3 -1.8 4.8 5.2 5.3 -5.0
Ulcerative Colitis (UC) 6.8 12.8 17.4 3.8 3.6 -4.0 3.8 -3.9 0.0 -3.9 -4.0 -3.6 -1.4 3.7 4.0 4.2 -3.9
Major Depression (MDD) 0.9 1.0 1.8 -0.9 -0.9 0.9 -1.0 1.1 1.2 1.0 0.9 0.9 1.3 -0.7 -1.1 -1.2 1.0
Reaction Time 0.3 0.6 1.9 -0.8 -0.9 0.7 -0.3 0.7 1.0 0.8 0.3 0.3 0.7 -1.4 -0.7 -0.1 0.9
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.7 0.4 0.7 -0.3 0.2 -0.3 0.8 -0.4 -0.6 -0.3 0.0 0.5 0.2 0.1 -0.2
Breast Cancer 0.3 0.6 1.5 -0.3 -1.1 0.7 -1.1 0.3 -0.3 0.6 1.2 1.2 0.5 0.3 -0.8 -0.9 0.2
Ovarian Cancer 0.2 0.2 1.0 0.4 1.0 -0.5 0.3 -0.1 -0.1 -0.4 -0.7 -0.4 0.4 0.0 0.6 0.2 -0.3
Prostate Cancer 1.2 1.7 6.4 -0.8 0.8 0.8 -1.7 1.5 1.7 0.9 1.4 1.6 -0.8 -2.5 -0.0 0.1 1.3
Age at First Birth 0.2 0.3 2.8 -0.4 -0.6 0.3 0.1 0.2 -1.7 0.3 0.1 -0.2 -0.2 -0.1 -0.5 -0.5 0.3
Bipolar Disorder (2011) 0.2 0.2 0.8 -0.3 -0.2 0.2 -0.5 0.5 -0.9 0.4 0.7 0.5 0.0 -0.3 -0.5 -0.7 0.3
Body Mass Index (BMI) (2010) 2.5 3.4 9.5 1.5 1.3 -1.8 2.2 -1.6 3.1 -1.6 -2.0 -2.2 -1.7 1.2 1.7 1.9 -1.5
Coronary Artery Disease (CAD) 11.0 13.1 18.1 4.0 4.0 -3.7 3.4 -4.2 -0.1 -4.0 -4.2 -3.4 -2.5 4.1 3.7 3.3 -4.0
Crohns Disease (2012) 3.5 5.6 8.7 2.4 2.6 -2.5 2.3 -2.6 1.1 -2.6 -2.5 -2.0 -0.9 2.3 2.9 3.0 -2.5
Mean Putamen Volume 3.9 4.5 5.9 2.3 2.4 -2.2 2.1 -2.2 1.3 -2.3 -2.4 -2.1 -0.7 2.3 2.4 2.1 -2.2
Fasting Glucose 1.0 1.1 7.4 -0.8 -1.1 0.9 -0.5 0.8 -2.7 0.8 0.7 0.6 0.3 -0.1 -1.1 -1.3 0.7
HbA1C 0.8 0.9 3.4 -0.6 -0.3 1.0 -1.2 0.8 -1.8 0.7 0.6 0.9 0.1 -0.1 -1.0 -1.6 0.6
HDL Cholesterol 0.3 0.5 2.3 0.4 0.5 -0.8 0.8 -0.4 1.5 -0.4 -0.3 -0.7 0.0 -0.5 0.8 1.2 -0.4
LDL Cholesterol 1.0 1.7 4.2 -1.4 -1.1 1.0 -0.7 1.3 1.9 1.3 0.7 0.8 0.8 -0.9 -1.7 -2.0 1.4
Lupus 0.3 0.4 2.4 -0.1 -0.2 0.4 -0.4 -0.2 -1.6 -0.0 -0.3 0.3 -1.2 0.7 -0.5 -0.9 0.0
Neuroticism (2016) 0.1 0.2 1.2 0.1 -0.2 0.2 -0.0 -0.3 -0.2 -0.3 -0.3 -0.1 -0.1 1.1 -0.3 -0.7 -0.2
Primary Biliary Cirrhosis 2.0 2.9 4.6 -1.8 -2.1 2.1 -2.0 1.6 -0.7 1.8 1.8 1.8 0.2 -1.2 -1.9 -1.9 1.6
Rheumatoid Arthritis 0.4 0.5 2.3 0.6 1.2 -0.4 0.0 -0.6 -0.5 -0.7 -0.4 -0.1 1.5 0.6 0.9 0.5 -0.6
Schizophrenia (2014) 1.2 2.6 6.5 -1.3 -1.5 1.5 -1.6 1.6 -2.2 1.5 1.6 1.4 0.7 -0.5 -2.1 -2.5 1.2
Triglycerides 0.1 0.1 0.4 0.1 0.2 -0.3 0.4 -0.1 -0.6 -0.2 -0.5 -0.5 -0.4 -0.1 0.2 0.3 -0.1
Type 2 Diabetes (T2D) (2012) 1.0 1.1 2.1 -1.2 -1.1 1.4 -1.3 0.9 -0.7 1.2 0.7 1.3 0.1 -0.8 -1.1 -1.1 1.2
Ulcerative Colitis 5.6 8.2 11.0 3.2 2.5 -3.1 2.9 -3.1 0.9 -3.1 -2.8 -2.7 -1.5 3.3 3.0 3.3 -3.3
Blood Eosinophil Count 11.5 88.3 127.7 -10.9 -11.2 11.3 -10.0 9.0 1.8 10.3 10.0 10.5 5.1 -10.5 -8.5 -7.0 10.3
Blood Platelet Count 4.2 48.5 75.7 -6.9 -7.0 7.0 -8.2 8.0 0.9 7.6 8.7 7.4 3.8 -7.8 -7.1 -6.2 7.1
Blood Red Count 0.1 1.3 4.2 1.2 0.8 -1.2 1.5 -0.5 -0.4 -0.9 -0.8 -1.8 -0.3 0.6 1.5 2.0 -1.0
Blood White Count 1.1 8.2 15.1 -3.6 -3.9 3.5 -2.5 2.6 -1.0 3.1 3.1 2.9 2.3 -3.2 -2.1 -1.4 3.2
Heel T-Score 2.5 20.0 35.8 -4.4 -4.6 4.5 -4.2 4.3 -5.4 4.5 4.1 4.1 2.7 -3.2 -5.2 -6.0 4.3
BMI 1.2 7.0 9.9 2.8 2.4 -2.5 2.5 -2.9 -1.3 -2.8 -3.1 -2.3 -1.9 2.9 3.1 2.8 -3.0
Height 0.5 9.3 19.6 -3.0 -3.5 2.6 -2.1 2.7 -4.2 2.9 3.3 2.4 1.2 -1.2 -4.0 -4.4 2.9
Waist Hip Ratio (WHR) 0.4 1.7 5.4 1.2 2.3 -1.0 -0.0 -0.9 2.3 -1.1 -1.0 0.1 0.8 -0.3 1.6 1.9 -0.8
Systolic Blood Pressure 1.0 5.0 13.5 2.3 3.7 -2.3 1.7 -2.1 1.1 -2.4 -2.5 -1.9 -2.0 1.3 2.6 2.4 -1.9
Smoking Status 2.8 6.7 8.3 -2.9 -2.5 2.7 -2.2 2.6 -2.6 2.8 2.3 2.4 2.2 -2.6 -2.6 -2.8 2.8
Allergy or Eczema 1.6 4.2 8.2 2.2 1.6 -1.6 1.5 -2.5 2.9 -2.2 -2.1 -1.5 0.6 2.1 2.1 2.7 -2.1
Cardiovascular Disease 0.1 0.2 1.7 0.5 1.3 -0.4 0.2 -0.2 -0.0 -0.4 -0.6 -0.2 -0.3 0.4 0.4 -0.2 -0.3
Hypothyroidism (self reported) 1.9 4.5 11.4 2.2 2.2 -2.0 1.7 -2.2 -3.4 -2.2 -2.4 -1.6 -0.5 2.3 2.0 1.5 -2.2
Respiratory disease 0.2 0.5 1.8 -0.6 -0.9 0.9 -0.3 0.4 -1.3 0.6 -0.1 -0.0 0.2 0.1 -0.9 -1.1 0.7
Type 2 Diabetes (T2D) (2018) 0.3 0.6 4.7 0.3 0.6 -0.0 0.1 -0.6 -0.3 -0.4 -0.8 0.4 2.2 0.6 0.8 0.6 -0.3
Lung FEV1/FVC ratio 2.0 10.4 15.7 3.7 3.5 -3.4 3.1 -3.4 0.9 -3.5 -3.2 -2.8 0.3 3.4 3.9 4.0 -3.6
Lung FVC 10.8 55.0 84.5 -7.8 -8.9 7.4 -7.3 8.0 -3.8 8.1 8.5 7.0 0.2 -6.3 -8.9 -9.2 7.3
Neuroticism 0.1 0.1 0.6 -0.2 -0.1 0.3 -0.7 0.1 -0.0 0.2 -0.0 0.4 0.8 0.4 -0.3 -0.7 0.1
Chronotype (morning person) 11.0 25.3 39.6 5.5 4.5 -5.2 4.9 -5.5 4.0 -5.4 -5.1 -4.9 -1.8 4.8 5.5 6.3 -5.5
Hair Pigment 0.4 12.3 18.7 -3.8 -3.4 3.8 -3.8 3.9 2.1 3.9 4.0 3.6 0.6 -4.3 -3.4 -3.2 3.8
Tanning 4.9 59.6 78.1 -8.0 -8.5 8.8 -8.7 7.5 -2.4 8.1 8.5 8.8 5.7 -6.8 -8.1 -7.7 7.9
Hand grip strength (left) 3.5 9.1 14.6 -2.7 -3.1 2.8 -3.0 3.4 -2.9 3.2 3.8 2.8 2.6 -2.1 -3.2 -3.5 2.8
Number of treatments/medications taken 0.6 1.0 2.4 1.1 1.6 -0.8 0.7 -1.1 0.0 -1.2 -1.2 -0.8 -0.1 1.1 1.2 0.9 -1.1
Average weekly spirits intake 0.1 0.2 0.5 -0.4 -0.4 0.4 -0.5 0.2 -0.4 0.3 0.7 0.7 -0.0 -0.1 -0.3 -0.4 0.2
Sensitivity / hurt feelings 0.4 0.7 2.7 0.8 0.9 -0.8 0.5 -0.7 1.6 -0.8 -0.9 -0.7 0.2 0.9 0.6 0.4 -0.8
Frequency of depressed mood in last 2 weeks 0.1 0.2 2.1 -0.2 0.2 0.0 0.0 -0.1 0.4 -0.0 -0.3 0.2 -1.4 -0.0 -0.2 -0.5 0.1
Hearing difficulty/problems: Yes 2.5 3.8 5.8 -2.2 -1.9 2.2 -2.0 2.0 -1.3 2.1 1.8 2.3 1.4 -2.4 -1.7 -1.5 2.3
Relative age of first facial hair 0.3 0.6 3.4 0.4 0.2 -0.2 0.3 -0.6 1.8 -0.5 -0.4 -0.2 1.7 0.7 0.5 0.8 -0.3
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 1.3 -0.3 -0.7 0.4 -0.0 0.1 1.1 0.2 0.2 0.1 -0.5 -0.1 -0.6 -0.4 0.3
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.9 0.5 0.8 -1.0 1.3 -0.1 1.7 -0.4 -0.7 -1.3 0.4 -0.1 0.5 0.6 -0.3
Ever had hysterectomy (womb removed) 0.8 0.9 2.4 -1.0 -1.1 0.7 -0.3 1.0 0.8 1.0 0.8 0.6 1.6 -1.1 -0.9 -0.6 1.0
Systolic blood pressure, automated reading 1.6 4.7 10.1 2.3 3.2 -2.1 1.7 -2.4 -0.8 -2.5 -2.4 -1.6 -1.3 1.7 2.6 2.4 -2.1
Eye problems/disorders: Diabetes related eye disease 1.8 2.0 4.0 1.3 1.1 -1.4 1.7 -1.5 1.0 -1.4 -2.0 -1.5 -0.6 1.5 1.4 1.2 -1.4
Angina 3.4 4.5 7.9 2.2 2.8 -2.1 2.2 -2.3 -0.8 -2.3 -2.8 -2.1 0.5 2.1 2.2 1.8 -2.0
Medication for hormone replacement therapy 0.3 0.4 1.8 -0.4 -0.5 0.1 -0.1 0.7 1.3 0.5 0.4 0.2 -0.6 -0.5 -0.8 -0.8 0.4
Vitamin and mineral supplements 3.2 4.3 7.0 -2.1 -2.2 2.2 -2.3 2.4 0.5 2.3 2.6 2.1 0.8 -2.3 -2.0 -1.6 2.2
Supplements: Zinc 0.3 0.3 1.7 -0.5 -0.6 0.3 -0.2 0.5 -0.6 0.5 0.3 0.2 -0.2 -0.1 -0.8 -1.3 0.3
Medication: Co-codamol 0.7 0.8 7.2 -0.3 -0.3 0.3 -0.1 0.9 2.7 0.5 0.3 -0.1 1.3 -0.8 -0.3 0.0 0.5
Medication: Metformin 0.2 0.4 1.3 0.4 0.6 -0.2 0.2 -0.4 -1.1 -0.4 -0.6 -0.0 1.0 0.6 0.8 0.4 -0.5
Diabetes (father) 0.3 0.4 4.1 0.2 0.0 -0.1 -0.1 -0.1 -2.0 -0.1 -0.2 0.0 0.7 0.7 0.0 -0.3 -0.3
Diabetes (mother) 1.0 1.3 3.8 -1.1 -0.4 1.3 -1.9 1.0 -0.9 1.0 1.2 1.9 0.3 -1.2 -0.7 -1.0 1.1
Severe depression (siblings) 0.4 0.5 1.4 0.6 0.2 -0.4 0.3 -0.9 -1.2 -0.7 -0.7 -0.2 -0.4 1.0 0.5 0.7 -0.7
Pack years adult smoking proportion 0.6 0.8 1.4 -1.1 -1.1 1.1 -0.7 0.7 1.2 0.9 0.9 1.0 -0.4 -0.8 -0.8 -0.7 1.0
Impedance of leg (right) 3.4 16.6 25.2 4.3 5.0 -4.1 3.9 -4.2 4.5 -4.3 -4.4 -3.9 0.3 3.7 4.4 4.3 -3.8
Leg fat-free mass (left) 0.7 3.5 20.6 -1.6 -2.2 1.5 -1.2 1.4 -4.5 1.5 1.6 1.3 -0.1 -0.4 -1.8 -2.2 1.2
Trunk fat percentage 3.5 14.0 21.1 4.0 3.8 -3.6 3.7 -4.2 -1.5 -4.1 -4.4 -3.6 -0.2 4.6 4.2 3.6 -4.1
Hand grip strength (right) 2.1 5.6 8.8 -2.1 -2.4 2.0 -2.1 2.8 -2.7 2.5 2.9 2.0 1.6 -1.7 -2.7 -3.0 2.2
Townsend deprivation index at recruitment 0.1 0.2 1.5 -0.1 0.3 0.2 0.1 -0.2 0.5 -0.1 -0.2 -0.0 1.2 -0.4 0.4 0.4 0.1
Current tobacco smoking 1.1 1.8 3.8 -1.5 -1.0 1.4 -1.2 1.4 -0.6 1.4 1.2 1.3 1.9 -1.6 -1.1 -1.1 1.5
Average weekly fortified wine intake 3.8 4.5 6.4 -2.2 -2.4 2.3 -2.2 1.9 -1.7 2.1 2.1 2.5 2.0 -1.4 -2.2 -2.3 2.0
Maternal smoking around birth 0.4 0.5 1.4 -0.8 -1.0 0.7 -0.3 0.5 -0.2 0.7 0.4 0.4 1.2 -0.2 -1.0 -1.1 0.7
Fed-up feelings 0.3 0.6 6.2 -0.3 0.2 0.3 -0.6 0.3 2.5 0.2 0.3 0.6 -0.6 -0.3 -0.2 -0.3 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 2.8 -0.3 0.2 0.2 -0.3 0.0 1.7 0.1 0.1 0.5 0.1 -0.3 0.3 0.3 0.1
Relative age voice broke 0.9 1.4 5.1 1.2 1.2 -1.0 0.6 -0.9 2.3 -1.1 -0.8 -0.5 0.7 0.7 1.4 1.8 -1.0
Taking other prescription medications 0.2 0.3 3.2 -0.1 0.1 0.2 0.3 0.1 -1.0 0.0 -0.3 -0.2 1.8 0.3 -0.1 -0.3 0.1
Age when periods started (menarche) 0.8 2.0 3.6 -1.4 -1.9 1.7 -1.7 1.3 -0.5 1.5 1.7 1.5 0.3 -1.2 -1.5 -1.1 1.4
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 4.6 -0.5 -0.6 0.3 -0.4 0.8 2.1 0.6 0.6 0.3 1.0 -0.6 -0.8 -0.8 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.2 0.8 1.1 -0.7 0.7 -0.6 -0.1 -0.7 -1.0 -0.9 0.3 0.4 0.7 0.6 -0.5
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 1.4 0.2 -0.5 -0.1 -0.1 -0.1 1.2 -0.1 0.2 0.3 0.9 0.5 -0.3 -0.2 -0.2
Qualifications: CSEs or equivalent 7.7 10.2 15.0 3.3 3.2 -3.0 2.8 -3.2 3.9 -3.3 -3.1 -3.0 -1.5 3.1 3.7 3.6 -3.3
Serious illness, injury or assault to yourself 3.2 3.9 5.8 2.1 2.3 -2.0 1.9 -2.1 1.0 -2.1 -2.4 -2.0 -0.4 2.2 2.1 2.0 -2.0
High blood pressure 0.1 0.1 1.3 0.1 1.2 -0.1 -0.2 -0.1 0.0 -0.2 -0.2 0.2 -0.4 -0.4 0.5 0.1 -0.0
Hayfever, allergic rhinitis or eczema 0.7 1.4 5.6 1.2 0.7 -0.7 0.5 -1.3 2.4 -1.2 -1.0 -0.6 1.1 1.3 1.1 1.4 -1.1
Multivitamins +/- minerals 1.8 2.2 3.7 1.6 1.9 -1.5 1.4 -1.7 0.1 -1.7 -1.9 -1.4 0.2 1.5 1.7 1.5 -1.5
Stomach or abdominal pain in last month 0.1 0.2 0.7 0.2 -0.5 0.1 -0.1 -0.1 0.8 -0.1 0.0 -0.1 -0.7 0.8 0.1 -0.0 -0.4
Supplements: Glucosamine 0.9 1.2 1.9 1.0 1.1 -1.1 1.4 -1.2 -0.6 -1.2 -1.4 -1.2 -1.3 1.3 0.8 0.3 -1.1
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 1.9 0.9 0.8 -1.0 1.2 -0.7 -0.0 -0.8 -0.9 -1.4 -0.7 0.5 1.1 1.2 -0.9
Medication: Atenolol 0.3 0.4 1.5 0.5 0.8 -0.7 0.3 -0.2 1.2 -0.4 -0.3 -0.4 0.1 -0.3 0.8 1.0 -0.4
Medication: Levothyroxine sodium 3.2 5.3 7.0 2.5 2.5 -2.4 2.3 -2.3 -2.6 -2.4 -2.6 -2.2 -1.1 2.5 2.3 1.8 -2.4
Sitting height 0.5 3.7 7.6 -1.8 -2.8 1.8 -1.3 1.8 -2.8 1.9 2.2 1.4 0.3 -0.6 -2.5 -2.3 1.8
Chronic bronchitis/emphysema (father) 2.6 3.0 9.9 -1.7 -1.7 1.9 -1.6 1.6 0.1 1.7 1.6 1.6 3.1 -1.8 -1.4 -0.9 1.9
High blood pressure (mother) 0.1 0.1 0.3 -0.2 0.5 0.2 -0.5 0.2 0.2 0.1 -0.0 0.4 0.4 -0.6 -0.0 -0.1 0.3
Body mass index (BMI) 0.2 0.7 1.9 0.7 0.6 -0.6 0.5 -0.8 -1.4 -0.8 -0.8 -0.5 -0.5 0.9 1.2 0.8 -1.0
Impedance of leg (left) 2.5 12.1 19.5 3.6 4.2 -3.5 3.4 -3.5 4.4 -3.6 -3.7 -3.4 0.5 3.0 3.6 3.8 -3.1
Leg predicted mass (left) 0.7 3.6 21.3 -1.6 -2.2 1.5 -1.2 1.4 -4.6 1.5 1.6 1.3 -0.1 -0.4 -1.8 -2.2 1.2
Trunk fat mass 1.7 7.4 12.6 2.9 2.6 -2.6 2.7 -3.1 -2.0 -3.0 -3.2 -2.5 -0.1 3.6 3.0 2.4 -3.0
Waist circumference 0.2 0.8 2.0 0.8 0.8 -0.6 0.7 -1.0 -1.4 -0.9 -1.1 -0.4 0.0 1.0 1.1 0.8 -0.9
Number of incorrect matches in round 0.1 0.1 0.9 -0.4 -0.4 0.1 0.2 0.3 0.1 0.3 0.2 -0.1 -0.5 -1.0 0.0 0.4 0.3
Past tobacco smoking 0.3 0.5 1.4 0.7 0.7 -0.7 0.6 -0.3 1.0 -0.6 -0.5 -0.9 -1.2 0.5 0.6 0.6 -0.7
Alcohol usually taken with meals 0.7 1.1 2.4 -1.0 -1.4 1.1 -0.8 0.7 0.4 1.0 1.0 1.0 0.7 -0.7 -1.6 -1.2 1.2
Nervous feelings 0.2 0.4 2.1 -0.2 -0.0 0.5 -0.7 0.0 1.3 0.1 0.1 0.5 1.5 0.1 -0.0 0.1 0.2
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.2 3.2 -1.6 -1.4 1.7 -1.7 1.4 -0.8 1.5 1.3 1.5 1.8 -1.0 -1.6 -1.8 1.5
Hearing difficulty/problems with background noise 0.3 0.5 1.1 -1.0 -0.7 1.0 -0.6 0.6 -0.1 0.8 0.7 0.9 -0.1 -1.1 -0.5 -0.5 1.0
Hair/balding pattern: Pattern 2 1.7 2.1 4.5 1.4 1.0 -1.5 1.7 -1.3 -1.1 -1.4 -1.9 -1.7 -1.8 2.1 0.9 0.5 -1.5
Had menopause 0.2 0.2 0.9 -0.1 0.4 -0.6 0.8 -0.1 -0.9 -0.2 -0.6 -0.5 -0.5 -0.2 0.0 -0.2 -0.0
Had other major operations 5.1 6.2 9.9 -2.8 -3.0 2.4 -1.9 2.8 -1.2 2.8 2.9 2.1 0.7 -2.1 -3.0 -3.1 2.7
Forced vital capacity (FVC) 7.9 30.3 51.4 -5.6 -6.2 5.5 -5.5 5.9 -2.9 5.9 6.5 5.3 1.4 -4.3 -6.8 -7.2 5.4
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 1.4 -0.9 -0.6 1.0 -0.9 0.8 -1.0 0.8 0.6 0.7 1.0 -0.5 -0.9 -1.2 0.9
Ever unenthusiastic/disinterested for a whole week 2.0 2.4 3.5 -1.6 -1.7 1.6 -1.5 1.6 -0.2 1.6 1.9 1.6 1.4 -1.4 -1.8 -1.7 1.7
Qualifications: None of the above 0.6 1.2 4.2 -1.3 -0.7 0.9 -0.9 1.2 -0.6 1.2 1.1 1.0 0.2 -2.1 -0.8 -0.9 1.2
Financial difficulties in last 2 years 1.4 1.9 2.6 -1.6 -1.4 1.5 -1.5 1.6 0.6 1.5 1.6 1.3 0.6 -1.6 -1.2 -1.1 1.5
Mouth/teeth dental problems 0.7 1.1 2.2 1.2 1.1 -0.8 0.7 -1.3 -0.4 -1.3 -1.0 -0.7 -0.9 1.5 1.1 1.0 -1.2
Heart attack 1.1 1.4 2.7 1.2 1.5 -1.5 1.6 -1.0 0.8 -1.2 -1.3 -1.6 -0.3 0.8 1.1 1.1 -1.1
Allergy 0.3 0.8 1.8 -1.0 -0.6 0.5 -0.5 1.2 -0.6 1.0 1.0 0.7 -1.0 -1.3 -0.8 -0.8 0.9
Pain all over the body in last month 0.1 0.1 0.4 0.2 0.3 -0.3 0.6 -0.4 0.5 -0.4 -0.4 -0.4 0.2 0.2 0.3 0.3 -0.2
Diabetes (self-reported) 0.9 1.3 2.7 0.8 1.0 -0.5 0.8 -1.3 -1.1 -1.1 -1.6 -0.3 1.6 1.4 1.4 1.3 -0.9
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.7 0.4 0.3 -0.2 0.2 -0.7 0.7 -0.5 -0.4 -0.0 0.5 0.4 0.7 0.8 -0.4
Medication: Ramipril 1.5 2.0 4.7 1.1 1.5 -1.4 1.9 -1.4 1.1 -1.3 -2.2 -1.8 -1.1 1.0 1.3 1.1 -1.0
Medication: Simvastatin 0.1 0.2 1.3 -0.3 -0.4 0.4 0.0 0.2 -0.2 0.3 -0.4 0.2 1.1 0.1 -0.3 -0.4 0.3
Fluid intelligence score 0.1 0.2 1.4 -0.2 -0.0 0.3 -0.6 0.4 1.2 0.3 0.4 0.4 -0.2 -0.1 -0.5 -0.6 0.3
Illnesses of siblings 0.1 0.2 0.5 0.4 -0.2 -0.2 0.4 -0.5 0.6 -0.4 -0.1 -0.4 -0.6 0.7 0.2 0.5 -0.4
Neuroticism score 0.2 0.3 2.4 0.3 0.4 -0.1 -0.3 -0.4 1.5 -0.4 -0.2 0.1 0.7 0.8 0.3 0.1 -0.4
Weight 0.1 0.7 7.6 0.2 -0.2 -0.1 0.3 -0.3 -2.8 -0.3 -0.3 -0.1 -0.2 1.0 0.2 -0.3 -0.4
Impedance of arm (right) 3.8 17.9 30.5 4.8 4.6 -4.3 4.2 -4.8 0.5 -4.8 -4.9 -4.1 1.3 5.5 4.2 3.7 -4.5
Arm fat percentage (right) 2.3 9.1 14.8 3.3 3.0 -2.8 2.8 -3.4 -1.7 -3.3 -3.5 -2.7 0.3 3.9 3.5 2.8 -3.4
Trunk fat-free mass 1.3 7.2 10.9 -2.9 -3.2 2.5 -2.1 2.8 -3.1 2.8 3.0 2.4 -0.4 -2.1 -3.0 -3.3 2.6
Hip circumference 0.5 2.0 10.3 0.9 0.0 -0.7 1.5 -1.2 -3.2 -1.0 -1.3 -1.3 -0.4 2.3 0.7 0.2 -1.3
Time employed in main current job 1.2 1.4 2.6 -1.2 -1.4 1.2 -1.4 1.3 0.0 1.3 1.6 1.2 0.8 -1.2 -1.1 -0.9 1.1
Alcohol intake versus 10 years previously 0.6 0.8 2.5 1.0 1.6 -0.8 0.4 -1.0 -0.8 -1.1 -1.0 -0.4 -0.1 0.6 1.2 0.8 -1.0
Father’s age at death 1.5 2.0 3.8 -1.6 -1.6 1.0 -0.6 1.5 -1.4 1.5 1.1 0.9 0.2 -1.6 -1.9 -1.9 1.6
Worrier / anxious feelings 0.8 1.6 4.5 1.4 1.0 -1.1 1.0 -1.6 0.4 -1.5 -1.2 -1.1 0.2 2.1 1.1 1.1 -1.5
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.3 -0.6 -0.4 0.3 0.0 0.6 0.6 0.5 0.1 -0.2 -0.0 -0.3 -0.7 -1.2 0.5
Falls in the last year 0.2 0.2 2.7 -0.0 -0.1 0.1 0.4 -0.1 0.1 -0.0 -0.2 -0.5 1.6 0.4 -0.1 -0.1 0.0
Hair/balding pattern: Pattern 3 0.2 0.3 2.2 0.4 0.2 -0.2 -0.0 -0.3 1.3 -0.3 -0.0 -0.2 -1.5 0.1 0.1 0.3 -0.4
Number of live births 0.8 1.1 2.2 1.1 0.6 -1.1 1.2 -1.1 0.2 -1.0 -1.2 -1.3 -0.4 0.9 1.1 1.5 -1.2
Forced expiratory volume in 1-second (FEV1) 4.6 15.5 27.6 -3.8 -4.5 3.8 -3.9 4.3 -2.2 4.2 4.9 3.7 1.6 -2.7 -4.9 -5.3 3.7
Pulse rate 1.3 2.2 4.0 -1.2 -2.0 1.6 -1.4 1.4 -1.9 1.6 1.8 1.4 0.5 -0.7 -1.6 -1.5 1.2
Happiness 2.0 2.4 4.1 -1.6 -1.4 1.8 -2.0 1.5 0.4 1.6 1.7 1.9 0.4 -1.5 -1.6 -1.6 1.6
Noisy workplace 3.9 4.8 8.2 2.3 2.6 -2.4 1.8 -2.2 1.7 -2.3 -2.2 -1.8 -0.8 1.6 2.8 2.9 -2.3
Qualifications: A levels/AS levels or equivalent 1.2 2.6 3.7 -1.6 -1.4 1.7 -1.9 1.8 -0.5 1.7 1.9 1.9 1.0 -1.4 -1.7 -1.8 1.7
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.9 -0.3 0.1 0.1 -0.0 0.3 0.9 0.2 0.1 -0.1 -0.1 -0.3 -0.3 -0.6 0.3
Mouth/teeth dental problems: Dentures 0.8 1.3 3.2 1.1 1.8 -1.6 1.4 -0.6 -0.6 -1.0 -1.2 -1.3 -0.8 -0.1 1.3 1.3 -0.9
Asthma 0.4 0.8 3.2 -0.9 -1.0 1.2 -0.6 0.5 -1.8 0.7 0.2 0.5 0.6 0.2 -1.0 -1.4 0.8
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 3.5 1.0 0.6 -1.2 1.9 -0.8 -0.5 -0.9 -1.2 -1.9 -1.6 1.4 0.6 0.2 -1.0
Medication: Cholesterol lowering 1.1 1.7 3.6 1.4 1.5 -1.2 1.4 -1.5 0.4 -1.4 -1.9 -1.1 -0.3 1.6 1.3 1.1 -1.3
Depression (self-reported) 1.3 1.6 4.7 -1.2 -1.1 1.3 -1.0 1.0 -2.2 1.1 1.0 1.2 0.3 -0.7 -1.5 -1.8 1.2
Medication: Lansoprazole 1.3 1.5 2.7 1.3 1.6 -1.3 1.2 -0.9 0.8 -1.2 -1.3 -1.5 -1.1 0.7 1.3 1.2 -1.1
Prospective memory result 2.2 2.7 5.4 1.6 1.3 -1.9 2.0 -1.7 0.0 -1.7 -1.6 -1.9 -0.6 1.2 1.9 2.3 -1.8
Lung cancer (father) 2.1 2.4 5.0 1.5 1.8 -1.6 1.5 -1.5 1.7 -1.6 -1.4 -1.6 -0.1 0.6 1.9 2.2 -1.4
Illnesses of mother 0.1 0.2 1.3 -0.1 -1.1 0.2 0.1 0.3 0.5 0.3 0.4 -0.2 -0.2 0.3 -0.6 -0.2 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 4.2 13.3 22.5 -3.6 -4.7 3.5 -3.4 3.8 -1.8 3.9 4.5 3.4 1.4 -2.4 -4.6 -4.7 3.3
Pulse wave Arterial Stiffness index 0.4 0.5 2.0 -0.4 -0.3 0.5 -0.8 0.5 -1.4 0.5 0.8 0.8 0.7 -0.2 -0.5 -0.7 0.4
Impedance of arm (left) 3.4 15.7 26.4 4.5 4.3 -4.1 4.0 -4.5 0.5 -4.4 -4.8 -4.0 0.9 5.1 3.8 3.4 -4.2
Arm fat mass (right) 0.8 3.3 6.4 1.9 1.6 -1.6 1.6 -2.0 -2.1 -1.9 -2.0 -1.5 -0.0 2.5 2.0 1.5 -2.1
Trunk predicted mass 1.3 7.4 11.2 -2.9 -3.2 2.5 -2.2 2.9 -3.1 2.9 3.0 2.4 -0.4 -2.2 -3.1 -3.3 2.6
Standing height 0.2 2.0 10.7 -1.0 -1.5 0.8 -0.5 0.8 -3.3 0.9 1.1 0.7 0.5 0.4 -1.8 -2.1 1.0
Length of working week for main job 0.5 0.6 2.6 0.6 0.7 -0.3 -0.3 -0.7 1.6 -0.6 -0.2 0.3 0.8 0.2 1.0 1.3 -0.6
Exposure to tobacco smoke at home 0.6 0.7 1.9 -0.8 -0.8 0.9 -0.9 0.6 -1.0 0.7 0.8 1.0 1.4 -0.4 -0.8 -0.7 0.8
Breastfed as a baby 0.7 0.8 1.5 -1.0 -1.1 0.9 -0.7 0.9 -0.7 0.9 1.1 0.7 0.3 -0.8 -1.1 -1.2 1.0
Tense / ‘highly strung’ 0.6 1.0 2.9 -0.9 -0.9 1.2 -1.2 0.7 -0.4 0.8 1.0 1.0 1.7 -0.3 -1.2 -1.2 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.1 0.3 -0.1 0.5 -0.2 0.6 -0.4 -0.1 -0.3 -0.5 -0.4 -0.3 0.2 0.0 -0.3 0.0
Hair/balding pattern: Pattern 4 1.4 3.5 6.2 -1.9 -1.2 1.7 -1.9 1.9 -1.0 1.9 2.0 2.1 2.0 -2.5 -1.7 -1.7 2.1
Birth weight of first child 3.4 6.2 9.1 -2.7 -3.0 2.7 -2.4 2.6 -0.5 2.8 2.5 2.5 2.0 -2.4 -2.7 -2.6 2.6
Peak expiratory flow (PEF) 2.9 6.8 10.8 -2.5 -3.2 2.5 -2.3 3.0 -1.4 2.9 3.3 2.2 2.0 -1.7 -3.1 -3.2 2.5
Pulse wave reflection index 0.2 0.3 1.2 -0.1 0.4 0.1 -0.8 -0.1 0.3 -0.1 0.6 1.1 1.1 -0.0 0.0 -0.2 -0.0
Ever highly irritable/argumentative for 2 days 0.1 0.1 1.2 0.1 0.1 -0.2 -0.0 0.2 1.1 0.0 0.2 0.0 0.5 -0.4 0.1 0.2 -0.0
Loud music exposure frequency 0.6 0.7 2.1 0.4 0.6 -0.7 1.4 -1.0 -0.2 -0.7 -1.3 -1.2 0.6 0.6 0.5 0.5 -0.4
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.8 0.4 0.1 -0.1 0.2 -0.2 -0.8 -0.3 -0.2 -0.3 0.0 0.9 0.0 -0.1 -0.4
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 2.0 1.2 0.6 -1.3 1.3 -1.2 0.3 -1.2 -1.0 -1.4 -0.5 1.3 1.1 1.2 -1.4
Blood clot in the leg (DVT) 0.6 0.7 1.1 -0.9 -0.9 0.9 -0.7 0.5 -1.1 0.7 0.9 0.9 1.0 -0.7 -0.8 -0.9 0.7
Medication: Paracetamol 0.3 0.5 2.7 -0.5 -0.7 0.3 0.1 0.9 1.6 0.7 0.4 -0.4 -0.2 -0.6 -0.6 -0.7 0.5
Headache pain in last month 1.5 2.7 4.6 -1.7 -1.5 1.5 -1.2 2.0 0.9 1.9 2.0 0.9 -0.6 -1.9 -1.9 -2.1 1.8
Medication for cholesterol, blood pressure or diabetes 1.4 2.3 3.8 -1.6 -1.8 1.3 -1.2 1.8 -1.0 1.7 1.9 1.0 0.0 -1.8 -1.7 -1.7 1.6
Glaucoma (self-reported) 1.9 2.3 3.7 1.4 1.7 -1.5 1.4 -1.8 0.6 -1.7 -1.9 -1.2 -0.1 1.3 1.9 1.8 -1.6
Gout (self-reported) 0.1 0.2 1.2 0.2 0.4 0.1 -0.5 0.0 0.2 -0.1 0.1 0.6 1.1 0.3 0.2 0.0 -0.1
Hypothyroidism/myxoedema (self-reported) 2.0 3.9 7.6 2.1 2.1 -1.8 1.6 -2.1 -2.8 -2.1 -2.4 -1.5 -0.3 2.3 1.9 1.5 -2.0
Medication: Amlodipine 0.0 0.1 0.2 -0.0 0.4 0.1 0.1 -0.1 -0.3 -0.2 -0.4 -0.2 -0.3 -0.1 0.2 0.2 0.1
Medication: Ventolin 100micrograms inhaler 1.4 1.8 4.0 -1.3 -1.6 1.7 -1.2 1.2 -2.0 1.3 1.1 1.1 0.3 -0.9 -1.6 -1.5 1.3
Birth weight 1.6 3.4 8.1 -1.7 -1.8 1.7 -2.0 1.7 2.9 1.7 2.0 2.0 1.5 -2.0 -1.4 -0.7 1.7
Chronic bronchitis/emphysema (mother) 0.2 0.2 2.2 -0.2 -0.2 0.1 -0.1 0.1 0.6 0.1 0.3 0.2 1.5 0.2 -0.2 -0.4 0.0
High blood pressure (siblings) 0.9 1.3 1.9 -1.2 -0.7 1.2 -1.3 1.2 -0.4 1.2 1.0 1.4 0.9 -1.3 -1.0 -1.2 1.2
Forced vital capacity (FVC), Best measure 8.0 29.4 48.7 -5.5 -6.7 5.5 -5.3 5.6 -2.9 5.8 6.3 5.2 1.7 -3.8 -6.8 -7.0 5.2
Body fat percentage 3.3 13.2 19.1 4.0 3.8 -3.5 3.5 -4.1 -0.9 -4.1 -4.2 -3.3 0.1 4.4 4.3 3.7 -4.0
Leg fat percentage (right) 2.0 7.4 11.8 2.9 3.1 -2.6 2.5 -3.0 0.6 -3.0 -3.2 -2.4 0.1 3.0 3.4 3.0 -3.0
Arm fat-free mass (right) 0.8 4.2 5.9 -2.2 -2.4 1.9 -1.6 2.2 -2.4 2.2 2.3 1.7 -1.0 -1.9 -2.2 -2.4 2.0
Exposure to tobacco smoke outside home 0.5 0.6 2.2 0.6 1.0 -0.6 0.5 -0.7 -1.5 -0.7 -0.9 -0.3 1.1 0.4 0.9 0.7 -0.6
Comparative body size at age 10 1.2 3.4 4.8 1.8 1.8 -2.1 2.0 -1.9 0.5 -1.9 -2.1 -1.9 -1.8 1.2 2.1 2.2 -1.9
Number of full brothers 1.1 1.4 2.7 1.2 1.3 -1.0 1.1 -1.4 0.6 -1.4 -1.5 -1.1 0.3 1.6 1.2 1.0 -1.2
Worry too long after embarrassment 2.0 3.4 5.7 -2.0 -2.0 2.3 -2.3 1.5 0.4 1.8 1.7 2.4 1.9 -1.5 -1.9 -1.6 1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.1 -0.8 -0.6 0.7 -0.4 0.1 -0.4 0.3 0.6 0.8 -1.1 -0.3 -0.7 -0.9 0.5
Wheeze or whistling in the chest in last year 2.6 4.7 6.8 -2.5 -2.1 2.5 -2.0 2.4 -0.5 2.5 1.6 1.9 1.8 -2.2 -2.3 -2.6 2.5
Number of children fathered 0.4 0.4 1.2 -0.5 -1.0 0.6 -0.3 0.6 0.2 0.7 0.3 0.1 1.1 0.0 -0.9 -0.9 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.2 0.7 -0.2 -0.3 0.3 -0.6 0.3 -0.2 0.3 0.5 0.4 0.8 -0.1 -0.5 -0.3 0.2
Age at first live birth 0.1 0.2 1.0 0.5 0.3 -0.2 -0.1 -0.5 -0.6 -0.5 -0.2 0.2 0.8 1.0 0.2 0.0 -0.6
Pulse wave peak to peak time 0.2 0.2 1.5 0.2 0.1 -0.3 0.6 -0.3 1.2 -0.3 -0.5 -0.7 -0.5 0.1 0.3 0.4 -0.2
Health satisfaction 0.7 1.0 1.4 1.1 1.1 -0.8 0.6 -1.1 -0.0 -1.1 -1.1 -0.6 -1.2 1.2 1.1 0.8 -1.2
Shortness of breath walking on level ground 0.5 0.6 3.9 -0.6 -0.2 0.5 -0.6 0.8 -2.0 0.6 0.2 0.7 0.7 -0.9 -0.2 -0.4 0.6
Qualifications: College or University degree 1.3 4.1 9.7 -1.9 -1.9 2.0 -2.0 2.1 -0.9 2.0 2.1 1.9 1.2 -1.2 -2.8 -3.1 2.0
Eye problems/disorders: None of the above 0.9 1.0 1.3 -1.0 -1.1 1.0 -0.9 0.9 1.1 1.0 1.1 0.9 -0.8 -1.1 -1.1 -0.9 1.1
Mouth/teeth dental problems: Loose teeth 1.3 1.5 2.3 -1.3 -1.1 1.4 -1.5 1.5 -0.5 1.4 1.3 1.2 0.5 -1.4 -1.1 -1.4 1.3
Emphysema/chronic bronchitis 0.7 0.8 5.1 -0.6 -0.4 0.7 -1.0 0.7 -2.2 0.6 0.7 1.0 0.3 -0.5 -0.6 -0.6 0.6
Medication for pain relief, constipation, heartburn 0.4 0.7 2.1 -0.7 -0.9 0.9 -1.4 0.6 -0.3 0.7 1.1 1.5 -0.1 -0.7 -0.6 -0.2 0.6
Neck or shoulder pain in last month 1.7 2.4 4.5 -1.7 -1.6 1.7 -1.4 1.9 -0.2 1.8 1.3 1.2 0.7 -1.5 -1.8 -2.1 1.7
Medication: Blood pressure 2.8 5.0 7.4 2.4 2.6 -2.2 1.9 -2.5 1.6 -2.5 -2.4 -1.7 -1.0 2.2 2.7 2.7 -2.3
Angina (self-reported) 4.0 5.2 9.0 2.4 2.9 -2.4 2.5 -2.5 -0.9 -2.5 -3.0 -2.3 0.4 2.4 2.3 1.9 -2.2
Migraine (self-reported) 0.6 0.8 6.2 -0.2 -0.0 -0.3 0.4 0.4 1.7 0.2 0.5 -0.5 -2.5 -0.5 -0.5 -0.6 0.2
Medication: Ibuprofen 1.5 1.8 4.1 1.2 0.7 -1.4 2.0 -1.1 -1.4 -1.1 -1.5 -2.0 -1.2 1.8 0.7 0.4 -1.3
Medication: Allopurinol 0.2 0.2 0.7 0.4 0.8 -0.4 0.1 -0.4 0.8 -0.5 -0.3 0.1 0.5 0.4 0.6 0.4 -0.4
Medication: Omeprazole 0.3 0.4 1.2 0.4 0.8 -0.2 0.3 -0.6 0.5 -0.6 -0.5 0.0 0.9 0.2 1.1 1.0 -0.4
Medication: Seretide 50 evohaler 0.3 0.3 2.9 -0.5 -0.4 0.1 0.5 0.2 0.2 0.3 -0.2 -0.4 -1.7 -0.4 -0.3 -0.5 0.3
Mean time to correctly identify matches 0.1 0.3 1.1 -0.6 -0.7 0.5 -0.3 0.4 0.6 0.5 0.0 0.3 0.3 -1.1 -0.5 -0.1 0.7
Heart disease (mother) 0.1 0.1 0.3 -0.3 0.0 0.3 -0.4 0.3 0.1 0.3 0.1 0.4 -0.4 -0.3 -0.4 -0.5 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.1 4.9 1.7 1.6 -1.2 0.9 -1.6 0.6 -1.6 -1.0 -1.2 0.9 1.2 2.0 2.2 -1.6
Whole body fat mass 1.4 5.8 9.9 2.5 2.3 -2.2 2.3 -2.7 -1.7 -2.7 -2.8 -2.1 -0.3 3.1 2.8 2.2 -2.7
Leg fat mass (right) 1.0 3.8 6.0 2.0 2.0 -1.8 1.9 -2.1 -1.0 -2.1 -2.2 -1.7 -0.3 2.4 2.4 1.9 -2.2
Arm predicted mass (right) 1.1 5.5 8.2 -2.6 -2.9 2.1 -1.8 2.5 -2.6 2.5 2.6 1.9 -0.9 -2.2 -2.5 -2.7 2.3
Pulse rate, automated reading 0.8 2.5 6.7 -1.3 -2.6 1.9 -1.6 1.4 -0.7 1.7 1.9 1.4 1.6 -0.9 -1.8 -1.0 1.4
Alcohol intake frequency. 0.4 1.0 3.6 0.7 0.6 -0.8 1.1 -0.7 1.9 -0.8 -1.0 -1.2 -1.0 0.6 0.8 0.9 -0.8
Comparative height size at age 10 0.5 2.5 13.5 1.0 1.3 -1.5 1.9 -1.1 -3.7 -1.2 -1.6 -1.6 -0.7 1.8 0.6 -0.3 -1.1
Number of full sisters 0.9 1.1 2.3 1.2 0.9 -0.9 0.8 -1.1 1.0 -1.1 -0.8 -0.7 0.5 1.3 1.4 1.5 -1.2
Suffer from ‘nerves’ 0.3 0.5 3.3 0.4 0.5 0.1 -0.4 -0.6 -0.6 -0.5 -0.3 0.5 1.8 1.2 0.2 0.0 -0.4
Overall health rating 0.1 0.3 1.0 0.3 0.9 -0.3 0.0 -0.2 -0.8 -0.3 -0.5 0.2 1.0 0.1 0.5 0.0 -0.3
Chest pain or discomfort 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.1 0.5 0.1 -0.4 -0.3 0.3 0.2 -0.1 -0.4 0.0
Had major operations 0.2 0.3 0.5 0.6 0.4 -0.6 0.5 -0.6 0.2 -0.6 -0.4 -0.4 -0.6 0.6 0.5 0.5 -0.7
Age at last live birth 0.2 0.3 2.0 0.6 0.0 -0.2 0.1 -0.6 -0.3 -0.5 -0.4 -0.0 0.6 1.4 0.2 0.1 -0.8
Family relationship satisfaction 0.9 1.2 3.3 -0.9 -0.7 1.1 -1.7 0.9 0.6 0.9 1.3 1.8 0.8 -1.0 -0.8 -0.7 1.0
Leg pain on walking 1.4 1.8 2.9 1.1 1.6 -1.4 1.5 -1.3 0.3 -1.4 -1.6 -1.2 -1.7 0.5 1.6 1.5 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.5 0.5 0.5 -0.0 -0.4 -0.6 0.9 -0.5 -0.2 0.3 1.0 0.2 0.9 1.2 -0.4
Commuting to job workplace: Car/motor vehicle 4.4 5.1 7.1 2.3 2.4 -2.4 2.5 -2.1 0.6 -2.4 -2.4 -2.6 -1.1 2.0 2.7 2.6 -2.3
Illness, injury, bereavement, stress in last 2 years 3.7 4.5 7.3 -2.0 -2.3 2.4 -2.6 2.0 -0.8 2.2 2.6 2.7 1.6 -1.9 -2.2 -1.8 2.0
Medication: Aspirin 1.9 2.6 4.4 1.6 1.8 -1.6 1.7 -1.7 1.4 -1.7 -2.1 -1.6 -0.1 1.4 1.8 1.8 -1.5
Supplements: Vitamin C 1.7 2.0 4.2 1.5 1.1 -1.6 1.7 -1.4 -1.1 -1.4 -1.7 -1.8 -0.6 2.0 1.0 0.6 -1.6
Knee pain experienced in last month 0.5 0.7 1.7 0.6 0.9 -0.8 1.2 -0.8 0.3 -0.8 -0.9 -1.3 -0.4 0.6 1.0 0.7 -0.8
Hypertension (Self-reported) 0.0 0.1 0.9 -0.0 1.0 -0.1 -0.2 0.0 0.2 -0.1 -0.1 0.2 -0.4 -0.4 0.3 -0.1 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 1.4 0.7 1.2 -0.8 1.0 -0.6 0.6 -0.8 -1.2 -1.2 0.2 0.4 0.9 0.8 -0.6
Illnesses of father: Heart disease 0.5 0.7 1.5 0.8 1.0 -1.0 1.2 -0.8 0.1 -0.9 -1.0 -1.1 -0.0 0.8 0.9 0.6 -0.8
Illnesses of siblings: Diabetes 0.8 1.0 1.8 1.1 1.3 -0.9 0.4 -1.2 -0.4 -1.2 -0.7 -0.2 0.9 1.1 1.3 1.0 -1.1
Smoking status: Previous 0.1 0.2 2.1 -0.0 -0.1 -0.0 0.1 -0.3 -1.4 -0.1 -0.1 0.2 0.4 0.3 -0.1 -0.2 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 1.9 0.7 0.4 -0.4 0.1 -0.6 1.4 -0.5 -0.3 -0.2 0.5 1.3 0.1 -0.1 -0.6
Whole body fat-free mass 1.0 5.7 14.4 -2.4 -2.9 2.1 -1.8 2.3 -3.8 2.4 2.5 2.0 -0.6 -1.5 -2.6 -2.9 2.1
Leg fat-free mass (right) 1.1 5.9 22.1 -2.3 -3.0 2.2 -1.8 2.1 -4.7 2.3 2.3 1.9 0.0 -1.1 -2.5 -2.8 1.9
Arm fat percentage (left) 2.1 8.6 13.5 3.2 2.9 -2.8 2.8 -3.2 -1.5 -3.2 -3.5 -2.6 0.1 3.7 3.4 2.8 -3.3
Average weekly red wine intake 0.5 0.8 4.3 -0.6 -0.6 0.8 -0.9 0.3 -0.5 0.6 0.6 1.1 2.1 0.0 -0.9 -1.0 0.6
Handedness (chirality/laterality): Left-handed 1.2 1.5 2.8 1.2 1.2 -1.1 1.1 -1.4 -0.8 -1.3 -1.3 -1.1 -1.7 1.2 1.1 1.0 -1.2
Mood swings 0.5 0.8 1.3 -1.1 -1.0 0.9 -0.7 0.9 1.0 1.0 0.6 0.6 -0.2 -0.9 -1.1 -1.1 1.0
Loneliness, isolation 0.3 0.4 1.4 -0.4 0.2 0.5 -1.2 0.6 1.1 0.4 0.5 1.0 0.5 -0.9 -0.0 -0.2 0.5
Long-standing illness, disability or infirmity 1.0 1.5 3.2 1.3 1.5 -0.9 1.0 -1.5 -0.5 -1.4 -1.6 -0.9 0.4 1.8 1.3 1.0 -1.3
Ever had bowel cancer screening 0.2 0.3 0.7 0.5 0.1 -0.4 0.4 -0.8 0.4 -0.6 -0.5 -0.3 0.1 0.8 0.5 0.6 -0.7
Diabetes diagnosed by doctor 1.0 1.7 3.6 1.1 1.1 -0.8 1.1 -1.7 -0.7 -1.3 -1.9 -0.6 1.0 1.8 1.6 1.4 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 3.1 0.4 0.3 -0.4 0.7 -0.4 1.7 -0.4 -0.4 -0.5 0.4 0.3 0.4 0.5 -0.3
Friendships satisfaction 0.3 0.4 4.1 -0.1 0.1 0.4 -0.9 -0.0 2.0 0.0 0.3 0.8 0.0 -0.2 -0.2 0.1 0.2
Qualifications: nursing, teaching 0.1 0.1 0.6 0.2 0.2 -0.2 0.4 -0.5 -0.1 -0.4 -0.2 -0.4 0.1 0.7 0.1 0.1 -0.4
Commuting to job workplace: Walk 3.9 4.2 5.5 2.1 2.3 -2.3 2.0 -2.1 1.7 -2.2 -2.2 -1.8 -1.3 1.6 2.3 2.3 -2.1
Eye problems/disorders: Cataract 0.4 0.5 5.0 0.3 0.3 -0.3 0.4 -0.3 -2.2 -0.3 -0.4 -0.5 0.1 0.1 0.4 0.5 -0.2
Mouth/teeth dental problems: Mouth ulcers 10.7 17.0 23.7 -4.5 -4.8 4.5 -4.1 4.0 0.1 4.4 4.5 4.3 3.0 -3.3 -4.8 -4.9 4.2
Medication for cholesterol 0.7 1.1 2.4 1.2 0.5 -0.9 0.8 -1.4 -0.4 -1.2 -0.9 -0.9 -0.4 1.5 1.1 1.4 -1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.3 2.7 4.5 -1.7 -1.8 1.8 -1.8 1.5 -1.7 1.7 1.5 1.7 0.7 -1.3 -1.9 -2.1 1.6
Back pain experienced in last month 0.3 0.4 1.2 -0.7 -0.5 0.6 -0.5 0.7 -0.5 0.6 0.7 0.6 -1.1 -0.5 -0.6 -1.0 0.5
Mineral and other dietary supplements 1.5 2.0 4.0 -1.2 -1.2 1.4 -1.8 1.6 0.6 1.5 2.0 1.5 1.8 -1.7 -1.0 -0.4 1.4
Breast cancer (self-reported) 1.3 1.6 3.1 1.4 1.3 -1.1 1.0 -1.5 0.6 -1.4 -1.3 -1.1 -0.8 1.8 1.4 1.3 -1.4
Asthma (self-reported) 0.3 0.6 1.9 -0.8 -0.9 1.1 -0.6 0.3 -1.4 0.5 0.1 0.5 0.7 0.2 -0.8 -1.0 0.6
Osteoporosis (self-reported) 0.8 1.0 2.0 -1.1 -1.4 1.1 -0.9 1.0 -0.2 1.1 1.1 0.9 1.1 -0.6 -0.9 -1.0 0.9
Osteoarthritis (self-reported) 0.6 0.8 6.9 -0.8 -0.2 0.4 0.0 0.5 2.6 0.5 0.2 0.1 -1.0 -1.1 -0.5 -0.5 0.7
Medication: Aspirin 2.1 2.7 4.7 1.7 1.9 -1.7 1.9 -1.6 0.9 -1.7 -2.2 -1.9 -0.3 1.4 1.8 1.7 -1.5
Medication: Gliclazide 0.3 0.3 0.7 0.3 0.0 -0.3 0.8 -0.6 -0.4 -0.4 -0.8 -0.8 0.7 0.5 0.7 0.8 -0.4
Illnesses of father: None of the above (group 1) 0.8 0.9 3.9 0.8 0.5 -0.8 0.7 -0.7 2.0 -0.7 -0.4 -0.7 -1.6 0.3 0.8 1.2 -0.8
Smoking status: Current 1.8 2.8 4.0 -1.9 -1.4 1.8 -1.7 1.8 -0.7 1.8 1.6 1.7 1.9 -2.0 -1.5 -1.5 1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.0 6.3 12.4 -2.4 -3.1 2.2 -2.3 2.7 -2.2 2.7 3.0 2.2 0.5 -1.7 -3.2 -3.5 2.1
Whole body water mass 1.0 5.7 14.4 -2.4 -2.9 2.1 -1.8 2.3 -3.8 2.4 2.5 2.0 -0.5 -1.5 -2.6 -2.9 2.1
Leg predicted mass (right) 1.1 5.9 22.2 -2.3 -3.0 2.2 -1.8 2.1 -4.7 2.3 2.3 1.9 0.0 -1.1 -2.6 -2.9 1.9
Arm fat mass (left) 0.8 3.2 5.8 1.8 1.5 -1.6 1.7 -1.9 -2.2 -1.9 -2.0 -1.5 -0.1 2.4 2.0 1.4 -2.0
Number of self-reported non-cancer illnesses 0.3 0.5 1.5 0.6 0.9 -0.5 0.9 -0.7 -0.0 -0.7 -1.2 -0.8 -0.5 0.8 0.6 0.2 -0.5
Average weekly champagne plus white wine intake 3.2 4.4 6.6 -2.2 -2.3 2.1 -2.0 2.4 0.3 2.3 2.4 1.9 0.1 -2.2 -2.6 -2.3 2.3
Miserableness 0.7 1.3 3.0 1.1 1.3 -0.9 0.7 -1.2 1.7 -1.2 -1.3 -0.7 -0.5 1.4 1.2 0.9 -1.1
Guilty feelings 2.2 3.3 4.8 -1.9 -2.0 2.1 -2.2 1.6 -0.0 1.8 1.9 2.0 2.2 -1.2 -1.9 -1.8 1.8
Wears glasses or contact lenses 0.2 0.2 1.1 0.2 0.2 -0.5 0.7 -0.4 1.0 -0.4 -0.2 -0.4 -0.2 0.1 0.3 0.5 -0.2
Ever taken oral contraceptive pill 1.1 1.2 2.3 1.2 1.5 -1.2 1.0 -0.9 -0.3 -1.1 -1.3 -1.2 -0.7 0.9 1.4 1.1 -1.1
Hearing aid user 0.2 0.2 0.5 0.5 0.6 -0.3 0.4 -0.4 0.3 -0.4 -0.3 -0.4 -0.5 0.4 0.6 0.7 -0.4
Mother’s age at death 0.9 1.1 5.8 -0.9 -0.8 0.4 0.0 0.9 -2.4 0.9 0.5 0.2 0.6 -0.4 -1.3 -1.8 0.8
Financial situation satisfaction 0.3 0.4 1.6 -0.1 -0.2 0.5 -1.2 0.2 0.8 0.2 0.6 1.1 1.3 0.0 0.1 0.2 0.1
Tinnitus: Yes, now most or all of the time 0.3 0.3 3.7 0.1 -0.4 0.0 -0.2 -0.2 -1.9 -0.1 0.1 0.2 -0.1 0.6 -0.2 -0.2 -0.2
Commuting to job workplace: Public transport 1.4 1.7 3.8 -1.3 -1.4 1.5 -1.6 0.9 -0.8 1.2 1.5 2.0 -0.6 -1.1 -1.4 -1.2 1.2
Eye problems/disorders: Glaucoma 0.7 0.9 1.6 0.9 1.2 -1.0 0.7 -1.1 0.8 -1.0 -1.0 -0.6 -0.3 0.5 1.2 1.1 -1.0
Medication: Blood pressure 0.2 0.5 2.0 -0.7 0.4 0.5 -0.6 0.9 -0.2 0.6 0.5 0.5 0.4 -1.4 -0.4 -0.7 0.9
Pain type(s) experienced in last month: Hip pain 0.8 1.0 2.4 0.8 1.1 -1.0 1.5 -0.8 -0.3 -1.0 -1.5 -1.6 -0.7 0.5 1.0 0.7 -0.8
Supplements: Fish oil (including cod liver oil) 2.1 2.8 4.6 1.6 1.5 -1.7 1.8 -1.9 -0.0 -1.8 -2.1 -1.6 -1.9 2.1 1.5 1.0 -1.8
High cholesterol (Self-reported) 0.2 0.4 1.6 0.2 0.5 -0.6 1.3 -0.2 0.7 -0.3 -0.9 -1.0 1.1 0.3 0.1 -0.2 -0.2
Medication: Bendroflumethiazide 0.6 0.9 1.7 0.9 1.0 -1.0 0.9 -0.7 1.3 -0.8 -0.7 -1.0 -0.9 0.6 1.1 1.2 -0.9
Medication: Paracetamol 0.2 0.3 2.4 -0.4 -0.4 0.4 -0.1 0.6 1.5 0.5 0.3 -0.1 -0.3 -0.5 -0.3 -0.4 0.4
Medication: Lisinopril 1.1 1.5 4.2 -0.8 -0.5 1.3 -2.0 0.8 -1.0 0.9 1.4 2.1 1.4 -0.4 -1.1 -1.3 0.9
Medication: Atorvastatin 0.4 0.5 1.9 0.8 1.4 -0.6 0.1 -1.0 0.2 -0.9 -0.6 0.2 0.7 0.9 0.7 0.4 -0.7
Illnesses of father: High blood pressure 0.7 0.8 4.1 -0.3 -0.3 0.5 -0.8 0.6 -2.0 0.5 0.4 0.8 2.0 0.1 -0.6 -0.7 0.3
Alcohol drinker status: Never 0.1 0.1 0.3 0.0 -0.3 -0.4 0.5 0.2 -0.3 0.1 -0.0 -0.5 -0.3 0.0 -0.3 -0.3 -0.0
Ever smoked 0.2 0.3 2.2 -0.4 -0.5 0.4 -0.4 0.1 -1.5 0.3 0.2 0.5 0.9 -0.1 -0.4 -0.4 0.4
Basal metabolic rate 0.6 3.5 13.0 -1.8 -2.3 1.6 -1.3 1.7 -3.6 1.7 1.8 1.4 -0.3 -0.9 -1.9 -2.3 1.5
Leg fat percentage (left) 1.2 4.5 7.4 2.2 2.3 -1.9 2.0 -2.4 0.5 -2.4 -2.5 -1.8 0.3 2.3 2.7 2.4 -2.3
Arm fat-free mass (left) 0.8 4.2 8.5 -2.1 -2.5 1.9 -1.7 2.1 -2.9 2.1 2.2 1.8 -0.3 -1.6 -2.1 -2.4 1.9
Number of operations (self-reported) 3.4 5.0 9.6 -2.5 -3.1 2.2 -1.7 2.4 0.4 2.5 2.6 1.9 0.8 -1.9 -2.7 -2.5 2.3
Average weekly beer plus cider intake 0.2 0.3 0.9 0.6 0.6 -0.7 0.7 -0.2 -0.4 -0.4 -0.5 -1.0 -0.2 0.4 0.6 0.5 -0.6
Irritability 0.1 0.1 0.9 0.3 0.2 -0.2 0.0 -0.1 -0.2 -0.2 -0.2 -0.1 0.9 0.4 0.2 0.1 -0.3
Risk taking 1.6 2.4 3.8 -1.6 -1.7 1.5 -1.6 1.5 0.6 1.6 1.4 1.7 1.9 -1.3 -1.7 -1.6 1.6
Ever had prostate specific antigen (PSA) test 0.3 0.3 4.0 -0.3 -0.4 0.1 0.0 0.1 2.0 0.2 0.4 0.3 -0.4 -0.4 -0.3 -0.1 0.2
Fractured/broken bones in last 5 years 0.9 1.1 4.4 1.0 0.6 -1.0 1.2 -0.8 -2.1 -0.9 -0.8 -1.2 0.6 1.3 0.6 0.4 -1.0
Age started oral contraceptive pill 3.0 3.8 5.0 -2.2 -1.9 2.1 -1.8 2.0 -1.4 2.1 2.0 1.7 0.8 -2.2 -2.2 -2.0 2.2
Diastolic blood pressure, automated reading 0.4 1.3 2.3 -0.9 -1.0 1.2 -1.5 0.8 -1.4 1.0 1.3 1.5 0.8 -0.5 -1.2 -1.1 0.9
Ever depressed for a whole week 0.5 0.7 1.8 -0.8 -1.0 0.9 -0.7 0.6 -0.1 0.7 0.8 0.8 1.3 -0.2 -0.9 -1.1 0.7
Unable to work because of sickness or disability 0.4 0.5 5.0 -0.4 -0.2 0.4 -0.0 0.1 1.0 0.3 -0.1 0.2 2.2 -0.1 -0.3 -0.4 0.4
Commuting to job workplace: Cycle 0.4 0.5 1.5 -0.9 -0.6 0.8 -0.4 0.7 -1.2 0.7 0.3 0.3 -0.2 -0.7 -0.8 -1.0 0.9
Myopia 2.1 3.0 5.3 -1.9 -1.5 1.6 -1.6 1.9 -0.6 1.9 1.6 1.6 -0.6 -2.0 -2.1 -2.3 1.9
Vascular/heart problems diagnosed by doctor 0.2 0.4 2.5 -0.5 -1.6 0.7 -0.4 0.5 0.0 0.7 0.9 0.4 0.1 -0.0 -0.8 -0.4 0.4
Cholesterol lowering medication 0.1 0.2 0.6 0.2 0.6 -0.4 0.8 -0.3 0.2 -0.4 -0.7 -0.6 0.8 0.3 0.2 -0.1 -0.1
Medication: Omeprazole (e.g. Zanprol) 1.1 1.4 2.8 1.2 1.4 -1.0 0.9 -1.4 -0.0 -1.3 -1.2 -0.7 0.7 1.1 1.7 1.6 -1.2
Pain experienced in last month 1.7 2.8 5.1 2.0 1.6 -1.7 1.3 -2.0 -0.0 -1.9 -1.8 -1.2 0.9 2.0 1.7 2.3 -1.8
Supplements: Calcium 1.1 1.2 2.2 0.9 0.9 -1.0 1.5 -1.4 -0.6 -1.2 -1.5 -1.2 -0.8 1.4 0.8 0.5 -1.1
Basal cell carcinoma (self-reported) 3.0 3.5 5.1 2.0 2.1 -2.1 2.1 -1.6 1.2 -1.9 -1.9 -2.2 -0.3 1.6 2.2 2.2 -1.8
Heart attack/myocardial infarction (self-reported) 0.8 1.1 2.3 1.0 1.2 -1.3 1.5 -0.8 0.7 -1.0 -1.2 -1.5 0.0 0.7 0.9 0.9 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 0.8 -0.5 -0.5 0.5 -0.3 0.1 -0.9 0.3 0.6 0.5 0.7 -0.3 -0.5 -0.5 0.3
Heart disease (siblings) 0.4 0.4 1.3 0.6 1.1 -1.0 0.7 -0.2 0.2 -0.5 -0.7 -0.7 0.9 -0.0 0.7 0.6 -0.5
Alcohol drinker status: Previous 0.9 1.1 4.5 -0.6 -0.8 0.9 -1.1 0.9 2.1 0.8 1.3 0.9 1.4 -0.6 -0.6 -0.3 0.7
Pack years of smoking 1.0 1.5 2.5 -1.5 -1.6 1.5 -1.0 1.0 1.0 1.3 1.3 1.3 -0.3 -1.1 -1.2 -1.1 1.4
Impedance of whole body 3.4 17.2 23.1 4.6 4.8 -4.2 4.1 -4.6 2.4 -4.6 -4.8 -4.1 0.7 4.7 4.2 4.1 -4.2
Leg fat mass (left) 0.6 2.4 3.9 1.6 1.4 -1.4 1.5 -1.7 -1.2 -1.7 -1.8 -1.4 -0.2 2.0 1.9 1.5 -1.7
Arm predicted mass (left) 0.6 3.1 8.5 -1.8 -2.0 1.5 -1.3 1.8 -2.9 1.8 2.0 1.4 -0.5 -1.3 -1.7 -2.0 1.5