[Hub]/) : Traits : Peak expiratory flow (PEF) :

chr5:147,063,674-148,712,150

Best TWAS P=5.71e-12 · Best GWAS P=3.17e-15 conditioned to 0.000695

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FBXO38 0.05 0.01 blup 489 0.02 1.5e-03 6.0 -6.1 1.1e-09 -0.72 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex HTR4 0.06 0.03 lasso 4 0.03 4.3e-05 6.9 5.4 7.4e-08 0.79 0.01 0.98 FALSE
3 GTEx Cells Transformed fibroblasts FBXO38 0.18 0.05 enet 35 0.10 1.1e-07 6.0 -5.7 1.0e-08 -0.60 0.61 0.36 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FBXO38 0.04 0.04 blup 52 0.04 4.8e-03 5.6 -6.9 5.7e-12 -0.75 0.05 0.14 TRUE
5 The Cancer Genome Atlas Colon Adenocarcinoma FBXO38 0.05 0.02 lasso 2 0.02 4.3e-02 5.1 -6.7 2.9e-11 -0.77 0.04 0.29 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FBXO38 0.02 0.03 enet 2 0.03 1.9e-04 -6.0 -6.7 2.0e-11 -0.76 0.04 0.58 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FBXO38 0.03 0.01 enet 6 0.01 5.0e-02 5.9 -6.3 3.0e-10 -0.53 0.08 0.04 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma FBXO38 0.11 0.02 blup 52 0.04 8.2e-06 6.0 -5.6 1.7e-08 -0.53 0.68 0.09 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma FBXO38 0.03 0.02 blup 51 0.02 7.7e-04 5.1 -5.3 1.3e-07 -0.63 0.54 0.08 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma FBXO38 0.05 0.01 blup 51 0.02 7.9e-03 -1.2 -5.3 1.4e-07 -0.66 0.05 0.17 FALSE
11 The Cancer Genome Atlas Rectum Adenocarcinoma FBXO38 0.13 0.17 enet 16 0.15 2.3e-04 5.9 -6.1 9.8e-10 -0.65 0.12 0.31 FALSE