[Hub]/) : Traits : Peak expiratory flow (PEF) :

chr5:156,123,995-157,697,754

Best TWAS P=8.63e-14 · Best GWAS P=8.93e-13 conditioned to 0.237

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ADAM19 0.09 0.08 lasso 6 0.05 5.6e-05 -7.1 -7.0 2.6e-12 0.99 0.00 0.99 FALSE
2 GTEx Breast Mammary Tissue ADAM19 0.11 0.10 lasso 1 0.06 3.6e-04 -7.1 -7.1 1.4e-12 1.00 0.01 0.99 FALSE
3 GTEx Breast Mammary Tissue (Female) ADAM19 0.11 0.14 lasso 6 0.10 5.1e-04 -7.1 -7.1 1.0e-12 0.98 0.01 0.92 FALSE
4 GTEx Cells Transformed fibroblasts ADAM19 0.16 0.02 enet 17 0.06 3.0e-05 1.1 -5.3 1.1e-07 0.63 0.06 0.93 FALSE
5 GTEx Esophagus Mucosa ADAM19 0.14 0.03 enet 19 0.09 2.4e-06 1.5 -5.5 3.6e-08 0.57 0.06 0.90 FALSE
6 GTEx Muscle Skeletal ADAM19 0.06 0.02 lasso 4 0.01 1.5e-02 -7.1 -7.5 8.6e-14 0.88 0.01 0.99 TRUE
7 GTEx Nerve Tibial ADAM19 0.34 0.16 enet 45 0.30 1.2e-21 -3.9 -5.4 6.4e-08 0.78 0.01 0.99 FALSE
8 GTEx Ovary ADAM19 0.32 0.11 lasso 9 0.08 6.5e-03 -3.7 -5.5 3.3e-08 0.65 0.04 0.74 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic ADAM19 0.10 0.01 lasso 4 0.08 5.2e-05 -4.8 -7.1 1.5e-12 0.75 0.02 0.98 FALSE
10 GTEx Skin Sun Exposed Lower leg ADAM19 0.07 0.04 lasso 6 0.06 1.2e-05 -4.5 -6.9 5.9e-12 0.80 0.02 0.98 FALSE
11 GTEx Testis ADAM19 0.16 0.00 enet 17 -0.01 6.7e-01 -3.9 -6.8 9.8e-12 0.82 0.02 0.89 FALSE
12 GTEx Whole Blood ADAM19 0.12 0.07 enet 20 0.07 9.8e-07 -4.8 -5.7 1.0e-08 0.57 0.91 0.09 FALSE
13 METSIM Adipose ADAM19 0.08 0.07 lasso 9 0.07 2.5e-10 -7.1 -7.1 1.3e-12 1.00 0.00 1.00 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADAM19 0.08 0.02 blup 159 0.03 5.3e-04 -4.4 -6.2 4.6e-10 0.70 0.03 0.83 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma ADAM19 0.09 0.03 lasso 4 0.05 2.4e-06 -7.1 -7.4 1.1e-13 0.83 0.01 0.99 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma ADAM19 0.05 0.01 blup 159 0.03 9.5e-04 1.2 -5.2 1.6e-07 0.57 0.06 0.22 FALSE