Best TWAS P=2.03e-10 · Best GWAS P=7.09e-10 conditioned to 0.116
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FANCE | 0.03 | 0.02 | bslmm | 420 | 0.01 | 1.7e-02 | -4.9 | -5.5 | 4.2e-08 | 0.58 | 0.30 | 0.20 | FALSE |
| 2 | NTR | Blood | ZNF76 | 0.01 | 0.00 | blup | 424 | 0.00 | 3.8e-02 | -5.0 | 6.4 | 2.0e-10 | -0.74 | 0.08 | 0.68 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | RPL10A | 0.03 | 0.00 | blup | 54 | 0.02 | 6.0e-03 | -5.4 | -5.3 | 1.2e-07 | 0.56 | 0.00 | 0.85 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TCP11 | 0.03 | 0.03 | blup | 49 | 0.04 | 6.6e-08 | -5.0 | -5.4 | 5.5e-08 | 0.92 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TCP11 | 0.03 | 0.00 | blup | 49 | 0.01 | 8.8e-03 | -5.2 | -5.3 | 1.4e-07 | 0.83 | 0.01 | 0.85 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TCP11 | 0.03 | 0.03 | blup | 49 | 0.03 | 3.5e-04 | -5.2 | -5.4 | 5.1e-08 | 0.88 | 0.02 | 0.95 | FALSE |
| 7 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TCP11 | 0.05 | 0.07 | lasso | 2 | 0.07 | 1.9e-05 | -5.1 | -5.1 | 3.1e-07 | 0.88 | 0.02 | 0.96 | FALSE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TCP11 | 0.08 | 0.11 | lasso | 2 | 0.11 | 3.4e-05 | -5.1 | -5.2 | 2.4e-07 | 0.89 | 0.02 | 0.94 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | C6orf106 | 0.08 | 0.00 | enet | 15 | 0.05 | 2.5e-05 | -3.4 | 5.7 | 1.4e-08 | -0.32 | 0.00 | 0.01 | TRUE |