Best TWAS P=8.8e-09 · Best GWAS P=1.5e-07 conditioned to 0.0278
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | DHDDS | 0.11 | 0.06 | lasso | 4 | 0.04 | 0.00066 | -5.2 | -5.8 | 8.8e-09 | 0.61 | 0.00 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RPS6KA1 | 0.11 | 0.05 | lasso | 6 | 0.07 | 0.00080 | -4.8 | 5.3 | 1.4e-07 | -0.88 | 0.01 | 0.76 | FALSE |