Best TWAS P=1.54e-07 · Best GWAS P=2.81e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | USP33 | 0.04 | 0.02 | blup | 455 | 0.02 | 0.002 | 4.1 | 5.1 | 2.9e-07 | 0.82 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Esophagus Mucosa | FAM73A | 0.09 | 0.01 | enet | 4 | 0.01 | 0.102 | 5.0 | -5.2 | 2.5e-07 | -0.96 | 0.03 | 0.68 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | USP33 | 0.04 | 0.01 | blup | 42 | 0.02 | 0.007 | 5.0 | 5.2 | 1.5e-07 | 0.96 | 0.02 | 0.84 | TRUE |