Best TWAS P=1.28e-16 · Best GWAS P=1.17e-14 conditioned to 0.883
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | THSD4 | 0.24 | 0.10 | lasso | 6 | 0.08 | 0.00002 | -7.7 | -8.3 | 1.3e-16 | 0.93 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | THSD4 | 0.24 | 0.02 | lasso | 8 | 0.00 | 0.24800 | -4.7 | 5.7 | 1.3e-08 | -0.60 | 0.05 | 0.65 | FALSE |