Best TWAS P=8.42e-08 · Best GWAS P=1.58e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CFDP1 | 0.08 | 0.04 | lasso | 4 | 0.04 | 1.6e-05 | 5.4 | 5.3 | 1.2e-07 | 0.93 | 0.02 | 0.98 | FALSE |
2 | GTEx | Adrenal Gland | TMEM170A | 0.11 | 0.06 | enet | 4 | 0.04 | 1.7e-02 | 5.4 | -5.4 | 8.4e-08 | -0.95 | 0.03 | 0.90 | TRUE |
3 | GTEx | Artery Aorta | BCAR1 | 0.18 | 0.13 | lasso | 3 | 0.11 | 9.8e-07 | 5.4 | -5.2 | 1.6e-07 | -0.95 | 0.02 | 0.98 | FALSE |
4 | GTEx | Artery Tibial | BCAR1 | 0.07 | 0.06 | lasso | 1 | 0.04 | 2.4e-04 | 5.1 | -5.1 | 3.1e-07 | -0.97 | 0.03 | 0.95 | FALSE |
5 | GTEx | Brain Cerebellum | BCAR1 | 0.18 | 0.08 | enet | 12 | 0.09 | 1.1e-03 | 5.5 | 5.2 | 2.4e-07 | 0.80 | 0.02 | 0.91 | FALSE |
6 | GTEx | Cells Transformed fibroblasts | CFDP1 | 0.17 | 0.20 | enet | 10 | 0.24 | 9.9e-18 | 5.5 | 5.2 | 1.7e-07 | 0.97 | 0.01 | 0.99 | FALSE |
7 | GTEx | Nerve Tibial | TMEM170A | 0.12 | 0.09 | enet | 7 | 0.11 | 4.1e-08 | 3.4 | 5.2 | 2.6e-07 | 0.87 | 0.03 | 0.97 | FALSE |