[Hub]/) : Traits : Diastolic blood pressure, automated reading : →

chr1:7,686,056-9,571,422

Best TWAS P=4.83e-15 · Best GWAS P=8.81e-13 conditioned to 0.349

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
27	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	-6.8	7.8	4.8e-15	0.85	0.02	0.95	TRUE
23	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	-7.0	7.6	4.0e-14	0.73	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	7.0	7.5	5.5e-14	0.98	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	RP5-1115A15.1	0.14	0.07	enet	20	0.10	2.6e-08	-7.1	7.5	9.1e-14	0.80	0.01	0.99	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	7.1	7.5	9.3e-14	0.97	0.01	0.99	FALSE
8	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	7.1	7.2	5.3e-13	0.98	0.01	0.99	FALSE
13	GTEx	Nerve Tibial	RERE	0.12	0.09	enet	16	0.11	5.6e-08	6.6	7.2	8.1e-13	0.92	0.02	0.98	FALSE
18	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	-7.1	7.2	8.5e-13	0.68	0.01	0.99	FALSE
12	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	-7.1	7.1	9.4e-13	0.64	0.01	0.98	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	RERE	0.02	0.03	lasso	2	0.03	4.7e-07	-7.0	7.1	1.4e-12	0.62	0.01	0.99	FALSE
14	GTEx	Pancreas	RERE	0.11	0.12	lasso	4	0.07	5.9e-04	7.1	7.0	2.0e-12	0.97	0.02	0.96	FALSE
6	GTEx	Breast Mammary Tissue	RP5-1115A15.1	0.10	0.07	lasso	2	0.03	7.0e-03	7.0	7.0	2.3e-12	1.00	0.01	0.98	FALSE
19	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	-6.8	7.0	2.6e-12	0.68	0.06	0.94	FALSE
20	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	7.0	7.0	3.7e-12	0.89	0.02	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	RERE	0.22	0.17	lasso	5	0.17	5.2e-09	-6.8	6.9	5.6e-12	0.62	0.05	0.95	FALSE
9	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	-6.8	6.8	1.3e-11	0.63	0.03	0.97	FALSE
5	GTEx	Breast Mammary Tissue	RERE	0.19	0.08	enet	10	0.14	8.0e-08	7.1	6.8	1.5e-11	0.82	0.01	0.98	FALSE
21	NTR	Blood	RERE	0.04	0.04	lasso	8	0.03	2.0e-11	-5.7	6.7	2.5e-11	0.66	0.26	0.74	FALSE
10	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	-6.8	6.4	1.4e-10	0.67	0.03	0.92	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	-5.8	6.2	4.3e-10	0.57	0.09	0.79	FALSE
16	GTEx	Skin Sun Exposed Lower leg	RERE	0.14	0.05	lasso	8	0.08	4.3e-07	-6.8	6.2	4.6e-10	0.52	0.03	0.97	FALSE
11	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	-5.6	5.9	4.6e-09	0.56	0.21	0.76	FALSE
7	GTEx	Breast Mammary Tissue (Male)	RP5-1115A15.1	0.18	0.07	lasso	3	0.06	1.7e-02	-3.0	5.8	6.9e-09	0.76	0.02	0.60	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SLC45A1	0.04	0.05	enet	9	0.02	1.8e-03	-5.3	-5.7	9.8e-09	-0.61	0.52	0.43	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	-6.8	5.5	4.4e-08	0.54	0.04	0.94	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RERE	0.04	0.02	blup	154	0.02	8.7e-04	-5.5	5.4	6.0e-08	0.37	0.09	0.68	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	RERE	0.06	0.01	blup	154	0.03	2.7e-04	-7.1	5.2	1.9e-07	0.39	0.03	0.92	FALSE