Best TWAS P=8.24e-10 · Best GWAS P=4.03e-10 conditioned to 2.04e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pancreas | RP5-1029K10.2 | 0.20 | 0.00 | enet | 49 | 0.06 | 0.00229 | 5.2 | 6.1 | 8.2e-10 | 0.38 | 0.04 | 0.52 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 0.00026 | 5.2 | -5.4 | 6.7e-08 | -0.80 | 0.03 | 0.94 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 0.00249 | 6.2 | -5.5 | 4.0e-08 | -0.79 | 0.01 | 0.96 | FALSE |