TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr20:46,551,079-48,140,682
Best TWAS P=2.39e-09 · Best GWAS P=3.16e-11 conditioned to 5.59e-13
46.6M
46.8M
47M
47.2M
47.4M
47.6M
47.8M
48M
48.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
PREX1
0.19
0.20
lasso
6
0.22
1.0e-22
-5.5
-6.0
2.4e-09
-0.09
0.37
0.63
TRUE
1
GTEx
Artery Aorta
PREX1
0.32
0.08
lasso
9
0.14
4.9e-08
-5.5
-5.5
3.0e-08
-0.14
0.47
0.53
FALSE