Best TWAS P=2.39e-09 · Best GWAS P=3.16e-11 conditioned to 5.59e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PREX1 | 0.32 | 0.08 | lasso | 9 | 0.14 | 4.9e-08 | -5.5 | -5.5 | 3.0e-08 | -0.14 | 0.47 | 0.53 | FALSE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PREX1 | 0.19 | 0.20 | lasso | 6 | 0.22 | 1.0e-22 | -5.5 | -6.0 | 2.4e-09 | -0.09 | 0.37 | 0.63 | TRUE |