Best TWAS P=5.65e-11 · Best GWAS P=4.84e-18 conditioned to 3.68e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | NELFCD | 0.32 | 0.20 | enet | 8 | 0.27 | 2.1e-18 | -4.4 | 5.1 | 3.0e-07 | 0.21 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Nerve Tibial | NELFCD | 0.30 | 0.17 | enet | 25 | 0.23 | 2.8e-16 | -4.1 | 5.3 | 9.5e-08 | 0.26 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TH1L | 0.07 | 0.00 | blup | 46 | 0.02 | 2.8e-02 | -4.1 | 5.3 | 1.1e-07 | 0.25 | 0.01 | 0.32 | TRUE |
| 4 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | 8.6 | -6.6 | 5.6e-11 | -0.69 | 0.01 | 0.73 | TRUE |
| 5 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | TUBB1 | 0.13 | 0.06 | blup | 50 | 0.04 | 2.3e-02 | -4.1 | 5.2 | 2.5e-07 | 0.12 | 0.01 | 0.37 | FALSE |