Best TWAS P=3.22e-08 · Best GWAS P=1.73e-08 conditioned to 0.0201
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TNRC6B | 0.02 | 0.01 | blup | 92 | 0.01 | 0.0027 | -4.7 | -5.3 | 1.4e-07 | 0.80 | 0.02 | 0.79 | FALSE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ADSL | 0.09 | 0.03 | lasso | 3 | 0.01 | 0.0771 | -5.1 | -5.5 | 3.2e-08 | 0.73 | 0.01 | 0.48 | TRUE |