TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr3:123,792,729-125,314,016
Best TWAS P=2.38e-10 · Best GWAS P=2.36e-09 conditioned to 0.487
123.8M
124M
124.2M
124.4M
124.6M
124.8M
125M
125.2M
125.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
ITGB5
0.34
0.28
lasso
4
0.32
4.4e-26
-5.9
-6.3
2.4e-10
0.89
0.01
0.99
TRUE
2
GTEx
Esophagus Gastroesophageal Junction
ITGB5
0.30
0.17
lasso
4
0.19
2.0e-07
4.7
-6.2
7.3e-10
0.77
0.04
0.94
FALSE
4
GTEx
Esophagus Muscularis
ITGB5
0.37
0.13
lasso
4
0.22
1.5e-13
5.6
-6.1
1.4e-09
0.72
0.07
0.93
FALSE
5
GTEx
Nerve Tibial
ITGB5
0.10
0.01
lasso
4
0.03
2.3e-03
-5.9
-5.9
4.3e-09
0.86
0.01
0.99
FALSE
6
METSIM
Adipose
ITGB5
0.05
0.04
lasso
3
0.04
2.2e-06
-5.9
5.9
4.8e-09
-0.95
0.01
0.99
FALSE
3
GTEx
Esophagus Mucosa
ITGB5
0.23
0.16
enet
29
0.21
8.1e-14
-5.9
5.2
1.9e-07
-0.83
0.01
0.99
FALSE