TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
:
←
→
chr3:121,346,656-122,821,385
Best TWAS P=3.49e-08 · Best GWAS P=9.25e-09 conditioned to 5.67e-05
121.4M
121.6M
121.8M
122M
122.2M
122.4M
122.6M
122.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CSTA
0.08
0.05
blup
64
0.06
4.7e-07
-4.9
5.5
3.5e-08
0.36
0.05
0.95
TRUE
2
GTEx
Nerve Tibial
FAM162A
0.07
0.05
lasso
4
0.05
2.1e-04
5.6
-5.5
4.1e-08
-0.95
0.02
0.94
FALSE
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
WDR5B
0.11
0.05
lasso
3
0.07
1.4e-05
4.5
5.2
1.9e-07
0.88
0.01
0.99
FALSE
1
GTEx
Esophagus Mucosa
CCDC58
0.12
0.08
lasso
6
0.05
5.0e-04
5.1
5.2
2.0e-07
0.88
0.02
0.96
FALSE
3
YFS
Blood
CSTA
0.40
0.20
enet
75
0.40
2.9e-141
3.6
5.1
3.1e-07
0.56
0.97
0.02
FALSE