[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr3:121,346,656-122,821,385

Best TWAS P=3.49e-08 · Best GWAS P=9.25e-09 conditioned to 5.67e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa CCDC58 0.12 0.08 lasso 6 0.05 5.0e-04 5.1 5.2 2.0e-07 0.88 0.02 0.96 FALSE
2 GTEx Nerve Tibial FAM162A 0.07 0.05 lasso 4 0.05 2.1e-04 5.6 -5.5 4.1e-08 -0.95 0.02 0.94 FALSE
3 YFS Blood CSTA 0.40 0.20 enet 75 0.40 2.9e-141 3.6 5.1 3.1e-07 0.56 0.97 0.02 FALSE
4 The Cancer Genome Atlas Prostate Adenocarcinoma CSTA 0.08 0.05 blup 64 0.06 4.7e-07 -4.9 5.5 3.5e-08 0.36 0.05 0.95 TRUE
5 The Cancer Genome Atlas Stomach Adenocarcinoma WDR5B 0.11 0.05 lasso 3 0.07 1.4e-05 4.5 5.2 1.9e-07 0.88 0.01 0.99 FALSE