Best TWAS P=3.49e-08 · Best GWAS P=9.25e-09 conditioned to 5.67e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CCDC58 | 0.12 | 0.08 | lasso | 6 | 0.05 | 5.0e-04 | 5.1 | 5.2 | 2.0e-07 | 0.88 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Nerve Tibial | FAM162A | 0.07 | 0.05 | lasso | 4 | 0.05 | 2.1e-04 | 5.6 | -5.5 | 4.1e-08 | -0.95 | 0.02 | 0.94 | FALSE |
| 3 | YFS | Blood | CSTA | 0.40 | 0.20 | enet | 75 | 0.40 | 2.9e-141 | 3.6 | 5.1 | 3.1e-07 | 0.56 | 0.97 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSTA | 0.08 | 0.05 | blup | 64 | 0.06 | 4.7e-07 | -4.9 | 5.5 | 3.5e-08 | 0.36 | 0.05 | 0.95 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | WDR5B | 0.11 | 0.05 | lasso | 3 | 0.07 | 1.4e-05 | 4.5 | 5.2 | 1.9e-07 | 0.88 | 0.01 | 0.99 | FALSE |