Best TWAS P=8.44e-10 · Best GWAS P=3.97e-08 conditioned to 0.111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | 5.2 | -6.1 | 8.4e-10 | -0.71 | 0.04 | 0.84 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | DCAF16 | 0.12 | 0.08 | lasso | 4 | 0.10 | 6.4e-06 | -4.7 | -5.3 | 1.2e-07 | -0.44 | 0.09 | 0.77 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | DCAF16 | 0.24 | 0.03 | enet | 18 | -0.01 | 4.4e-01 | 4.6 | -5.2 | 2.3e-07 | -0.69 | 0.03 | 0.65 | FALSE |
| 4 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | -4.6 | -5.4 | 8.2e-08 | -0.57 | 0.06 | 0.48 | FALSE |
| 5 | GTEx | Thyroid | DCAF16 | 0.11 | 0.02 | lasso | 5 | 0.03 | 2.3e-03 | -4.6 | -5.7 | 9.3e-09 | -0.47 | 0.16 | 0.70 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | -4.5 | -5.7 | 1.2e-08 | -0.55 | 0.16 | 0.58 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NCAPG | 0.02 | 0.03 | lasso | 1 | 0.02 | 9.0e-04 | 5.4 | 5.4 | 7.0e-08 | 0.81 | 0.01 | 0.84 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCAF16 | 0.04 | 0.04 | blup | 31 | 0.04 | 2.2e-05 | -4.6 | -6.0 | 1.9e-09 | -0.50 | 0.15 | 0.55 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | -4.4 | -5.5 | 2.9e-08 | -0.56 | 0.16 | 0.74 | FALSE |