[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr3:157,125,828-159,106,064

Best TWAS P=1.24e-10 · Best GWAS P=1.56e-09 conditioned to 0.741

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RSRC1	0.15	0.17	lasso	4	0.18	9.7e-15	6.0	-6.2	7.0e-10	-0.94	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	RP11-538P18.2	0.15	0.15	lasso	7	0.18	9.4e-15	5.9	-6.0	2.4e-09	-0.93	0.01	0.99	FALSE
3	GTEx	Artery Aorta	RP11-538P18.2	0.11	0.09	lasso	3	0.08	2.9e-05	6.0	-6.0	2.5e-09	-0.96	0.01	0.99	FALSE
4	GTEx	Artery Tibial	RSRC1	0.13	0.13	lasso	6	0.11	3.5e-09	6.0	-6.1	1.3e-09	-0.97	0.00	1.00	FALSE
5	GTEx	Artery Tibial	RP11-538P18.2	0.17	0.14	enet	24	0.21	3.7e-16	6.0	-5.6	1.9e-08	-0.86	0.01	0.99	FALSE
6	GTEx	Brain Cortex	RSRC1	0.43	0.02	lasso	7	0.00	2.3e-01	5.4	-5.4	5.7e-08	-0.64	0.07	0.21	FALSE
7	GTEx	Breast Mammary Tissue	RSRC1	0.14	0.10	lasso	6	0.13	4.9e-07	6.0	-6.4	1.2e-10	-0.92	0.01	0.99	TRUE
8	GTEx	Breast Mammary Tissue	RP11-538P18.2	0.17	0.14	lasso	6	0.16	1.2e-08	5.9	-5.8	6.9e-09	-0.96	0.01	0.99	FALSE
9	GTEx	Breast Mammary Tissue (Male)	RP11-538P18.2	0.30	0.11	lasso	6	0.10	3.3e-03	6.0	-6.0	1.9e-09	-0.93	0.02	0.75	FALSE
10	GTEx	Breast Mammary Tissue (Female)	RP11-538P18.2	0.20	0.14	enet	13	0.17	9.4e-06	4.8	-5.2	2.0e-07	-0.86	0.06	0.91	FALSE
11	GTEx	Cells Transformed fibroblasts	RP11-538P18.2	0.10	0.08	enet	10	0.13	5.1e-10	5.9	-5.7	9.1e-09	-0.90	0.01	0.99	FALSE
12	GTEx	Colon Transverse	RP11-538P18.2	0.07	0.10	lasso	6	0.08	8.4e-05	5.9	-5.6	1.7e-08	-0.95	0.02	0.96	FALSE
13	GTEx	Esophagus Mucosa	RP11-538P18.2	0.12	0.10	lasso	5	0.14	1.9e-09	6.0	-5.8	8.4e-09	-0.85	0.01	0.99	FALSE
14	GTEx	Lung	RSRC1	0.09	0.05	enet	12	0.06	3.5e-05	4.9	-5.3	1.3e-07	-0.86	0.02	0.98	FALSE
15	GTEx	Lung	RP11-538P18.2	0.16	0.11	enet	17	0.17	6.6e-13	4.8	-6.0	2.0e-09	-0.91	0.07	0.93	FALSE
16	GTEx	Muscle Skeletal	RSRC1	0.11	0.06	lasso	2	0.04	1.5e-04	6.0	-6.0	2.0e-09	-0.97	0.01	0.99	FALSE
17	GTEx	Muscle Skeletal	RP11-538P18.2	0.09	0.08	lasso	2	0.05	1.3e-05	6.0	-6.0	2.0e-09	-0.96	0.01	0.99	FALSE
18	GTEx	Nerve Tibial	RSRC1	0.10	0.15	lasso	3	0.12	9.9e-09	6.0	-6.1	1.3e-09	-0.97	0.00	1.00	FALSE
19	GTEx	Nerve Tibial	RP11-538P18.2	0.21	0.18	enet	16	0.20	2.1e-14	6.0	-5.7	9.1e-09	-0.91	0.00	1.00	FALSE
20	GTEx	Ovary	RP11-538P18.2	0.23	0.08	lasso	6	0.13	4.5e-04	5.9	-5.9	3.6e-09	-0.83	0.03	0.69	FALSE
21	GTEx	Pancreas	RP11-538P18.2	0.14	0.02	lasso	11	0.02	5.3e-02	3.6	-5.2	1.9e-07	-0.79	0.04	0.83	FALSE
22	GTEx	Pituitary	RP11-538P18.2	0.17	0.03	lasso	8	0.03	6.9e-02	5.9	-5.2	2.5e-07	-0.91	0.03	0.74	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	RSRC1	0.07	0.09	lasso	2	0.06	3.7e-04	6.0	-5.8	5.3e-09	-0.95	0.01	0.97	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	RP11-538P18.2	0.09	0.10	enet	13	0.12	6.8e-07	4.8	-5.4	6.4e-08	-0.83	0.11	0.88	FALSE
25	GTEx	Skin Sun Exposed Lower leg	RSRC1	0.09	0.09	lasso	2	0.08	4.4e-07	6.0	-6.3	3.9e-10	-0.96	0.00	1.00	FALSE
26	GTEx	Skin Sun Exposed Lower leg	RP11-538P18.2	0.13	0.12	enet	11	0.14	7.8e-12	6.0	-5.9	2.7e-09	-0.93	0.00	1.00	FALSE
27	GTEx	Stomach	RP11-538P18.2	0.06	0.04	lasso	2	0.04	3.4e-03	5.9	-5.9	4.7e-09	-0.97	0.02	0.96	FALSE
28	GTEx	Testis	GFM1	0.16	0.11	lasso	8	0.11	1.3e-05	5.2	5.2	2.3e-07	0.60	0.24	0.68	FALSE
29	GTEx	Thyroid	RP11-538P18.2	0.14	0.13	lasso	5	0.12	1.2e-09	6.0	-6.4	1.9e-10	-0.91	0.01	0.99	FALSE
30	METSIM	Adipose	RSRC1	0.14	0.19	blup	532	0.21	6.0e-31	5.9	-5.5	3.5e-08	-0.84	0.01	0.99	FALSE
31	YFS	Blood	RSRC1	0.13	0.13	enet	26	0.17	8.8e-54	5.5	-6.3	3.4e-10	-0.87	0.09	0.91	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	RSRC1	0.04	0.03	enet	11	0.04	4.5e-09	4.2	-5.3	1.4e-07	-0.80	0.04	0.96	FALSE