[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr5:60,903,201-62,529,686

Best TWAS P=4.91e-12 · Best GWAS P=2.26e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose KIF2A 0.05 0.02 lasso 4 0.02 1.1e-03 4.8 -5.8 6.8e-09 -0.63 0.10 0.49 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma IPO11 0.08 0.02 lasso 4 0.01 9.3e-02 6.5 6.5 7.0e-11 0.99 0.02 0.93 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma DIMT1L 0.09 0.04 lasso 3 0.04 3.0e-08 6.2 5.6 2.3e-08 0.87 0.06 0.94 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma IPO11 0.09 0.06 blup 127 0.07 1.7e-13 6.5 6.2 4.6e-10 0.92 0.02 0.98 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma KIF2A 0.05 0.02 blup 71 0.02 5.4e-06 6.5 6.6 4.8e-11 0.85 0.01 0.99 FALSE
6 The Cancer Genome Atlas Esophageal Carcinoma IPO11 0.14 0.01 lasso 12 0.01 1.1e-01 6.5 6.5 9.4e-11 0.98 0.02 0.87 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DIMT1L 0.26 0.13 lasso 1 0.10 2.3e-06 6.2 6.2 6.0e-10 0.92 0.02 0.97 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma IPO11 0.06 0.03 lasso 3 0.03 4.2e-04 6.5 6.9 4.9e-12 0.96 0.02 0.94 TRUE
9 The Cancer Genome Atlas Lung Adenocarcinoma KIF2A 0.06 0.02 lasso 1 0.01 3.9e-02 6.5 6.5 5.8e-11 0.92 0.01 0.89 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DIMT1L 0.06 0.01 blup 53 0.03 7.2e-05 6.2 5.3 1.1e-07 0.80 0.01 0.90 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO11 0.08 0.04 blup 127 0.05 4.2e-06 6.5 6.1 8.8e-10 0.98 0.02 0.98 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIF2A 0.05 0.03 lasso 2 0.02 1.7e-03 6.5 6.5 8.7e-11 0.92 0.01 0.96 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma IPO11 0.03 0.00 blup 127 0.01 3.0e-02 6.6 6.2 4.6e-10 0.83 0.02 0.57 FALSE
14 The Cancer Genome Atlas Rectum Adenocarcinoma DIMT1L 0.33 0.15 lasso 6 0.13 6.0e-04 6.4 6.0 2.1e-09 0.96 0.01 0.83 FALSE
15 The Cancer Genome Atlas Soft Tissue Sarcoma IPO11 0.08 0.01 lasso 5 0.04 1.3e-03 4.8 6.2 5.4e-10 0.85 0.02 0.73 FALSE
16 The Cancer Genome Atlas Stomach Adenocarcinoma IPO11 0.14 0.05 lasso 3 0.03 1.6e-03 6.7 6.7 2.6e-11 0.91 0.02 0.95 FALSE