Best TWAS P=4.66e-17 · Best GWAS P=1.48e-17 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | CPEB4 | 0.10 | 0.07 | lasso | 2 | 0.06 | 1.3e-08 | -8.5 | 8.0 | 1.2e-15 | -0.97 | 0 | 1 | FALSE |
2 | YFS | Blood | CPEB4 | 0.58 | 0.72 | bslmm | 632 | 0.73 | 0.0e+00 | -8.5 | -8.4 | 4.7e-17 | 0.99 | 0 | 1 | TRUE |