Best TWAS P=3.86e-13 · Best GWAS P=2.92e-13 conditioned to 0.00139
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CSNK1G3 | 0.11 | 0.07 | lasso | 2 | 0.01 | 6.5e-02 | 7.1 | 7.0 | 3.1e-12 | 0.98 | 0.01 | 0.96 | FALSE |
| 2 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | 6.3 | -7.3 | 3.9e-13 | -0.68 | 0.12 | 0.50 | TRUE |
| 3 | GTEx | Esophagus Mucosa | CSNK1G3 | 0.14 | 0.05 | lasso | 3 | 0.07 | 2.0e-05 | -5.3 | -5.5 | 4.0e-08 | -0.35 | 0.85 | 0.03 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | -5.5 | -6.6 | 4.3e-11 | -0.55 | 0.02 | 0.55 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | -3.2 | -6.0 | 2.6e-09 | -0.41 | 0.04 | 0.71 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | 6.3 | -6.3 | 3.5e-10 | -0.63 | 0.04 | 0.81 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | CSNK1G3 | 0.06 | 0.05 | lasso | 2 | 0.04 | 2.0e-05 | -5.3 | -5.2 | 2.0e-07 | -0.37 | 0.68 | 0.05 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | 6.7 | -6.8 | 1.0e-11 | -0.54 | 0.01 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | -4.5 | -6.8 | 9.9e-12 | -0.62 | 0.36 | 0.56 | FALSE |