Best TWAS P=5.23e-10 · Best GWAS P=1.04e-13 conditioned to 1.25e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | GTEx | Muscle Skeletal | NOC3L | 0.09 | 0.05 | enet | 7 | 0.05 | 7.5e-06 | -5.0 | -6.2 | 5.2e-10 | -0.54 | 0.83 | 0.05 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NOC3L | 0.05 | 0.01 | enet | 5 | 0.03 | 6.3e-04 | 6.5 | -6.1 | 1.2e-09 | -0.76 | 0.01 | 0.95 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | NOC3L | 0.10 | 0.11 | lasso | 5 | 0.12 | 4.7e-14 | -5.2 | -6.0 | 1.9e-09 | -0.53 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Adrenal Gland | NOC3L | 0.21 | 0.10 | lasso | 5 | 0.18 | 4.4e-07 | -2.7 | -5.7 | 1.4e-08 | -0.52 | 0.78 | 0.08 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NOC3L | 0.08 | 0.06 | lasso | 2 | 0.04 | 5.8e-03 | -5.4 | -5.4 | 7.5e-08 | -0.51 | 0.04 | 0.08 | FALSE |
| 3 | GTEx | Colon Sigmoid | NOC3L | 0.34 | 0.10 | lasso | 10 | 0.12 | 3.7e-05 | -2.7 | -5.1 | 2.9e-07 | -0.50 | 0.50 | 0.39 | FALSE |