TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr1:183,961,643-185,416,670
Best TWAS P=3.65e-08 · Best GWAS P=1.47e-06 conditioned to 0.634
184M
184.2M
184.4M
184.6M
184.8M
185M
185.2M
185.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
EDEM3
0.23
0.16
enet
24
0.19
1.7e-14
4.5
-5.5
3.7e-08
-0.82
0.04
0.94
TRUE
1
CommonMind
Brain Pre-frontal Cortex
EDEM3
0.11
0.08
lasso
14
0.11
2.3e-13
4.7
-5.3
8.9e-08
-0.79
0.03
0.95
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
EDEM3
0.05
0.06
enet
7
0.08
8.7e-10
4.6
-5.2
2.0e-07
-0.82
0.03
0.95
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
EDEM3
0.04
0.04
blup
66
0.04
2.0e-05
4.7
-5.2
2.1e-07
-0.90
0.02
0.96
FALSE