Best TWAS P=1.02e-09 · Best GWAS P=7.02e-13 conditioned to 3.33e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SHISA4 | 0.09 | 0.04 | lasso | 3 | 0.03 | 1.5e-03 | -5.1 | -5.3 | 9.5e-08 | 0.28 | 0.29 | 0.05 | FALSE |
| 2 | GTEx | Esophagus Muscularis | LMOD1 | 0.16 | 0.09 | enet | 9 | 0.08 | 7.8e-06 | 6.3 | -6.0 | 1.8e-09 | 0.20 | 0.24 | 0.74 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RP11-307B6.3 | 0.20 | 0.12 | lasso | 3 | 0.12 | 5.6e-08 | 6.3 | -5.9 | 4.0e-09 | 0.19 | 0.25 | 0.75 | FALSE |
| 4 | METSIM | Adipose | LMOD1 | 0.09 | 0.07 | bslmm | 496 | 0.07 | 4.8e-10 | 6.4 | -5.5 | 3.7e-08 | 0.16 | 0.22 | 0.78 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SHISA4 | 0.03 | 0.01 | enet | 5 | 0.00 | 2.5e-01 | -5.3 | -5.3 | 1.4e-07 | 0.31 | 0.04 | 0.18 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LMOD1 | 0.02 | 0.01 | blup | 59 | 0.02 | 1.2e-04 | 6.3 | -5.8 | 7.5e-09 | 0.20 | 0.01 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | LMOD1 | 0.07 | 0.06 | blup | 59 | 0.03 | 2.1e-02 | 6.4 | -6.1 | 1.0e-09 | 0.23 | 0.01 | 0.85 | TRUE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LMOD1 | 0.04 | 0.07 | enet | 6 | 0.05 | 9.4e-07 | -5.3 | -6.0 | 2.2e-09 | 0.27 | 0.22 | 0.78 | FALSE |