[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr1:112,312,154-114,366,434

Best TWAS P=1.69e-13 · Best GWAS P=1.19e-13 conditioned to 4.45e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	WNT2B	0.05	0.02	blup	46	0.05	4.7e-04	-6.0	-7.4	1.7e-13	0.45	0.05	0.13	TRUE
15	GTEx	Spleen	SLC16A1	0.16	0.08	lasso	5	0.07	8.3e-03	-6.9	-7.1	1.6e-12	-0.10	0.06	0.50	TRUE
24	The Cancer Genome Atlas	Thyroid Carcinoma	RHOC	0.04	0.03	enet	9	0.04	1.4e-04	-6.1	-7.2	4.5e-13	0.49	0.20	0.22	FALSE
2	CommonMind	Brain Pre-frontal Cortex	WNT2B	0.43	0.46	enet	44	0.47	7.4e-64	6.9	7.1	1.2e-12	-0.25	0.08	0.92	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC16A1	0.09	0.11	lasso	2	0.11	3.0e-11	-6.9	7.0	3.1e-12	0.05	0.01	0.99	FALSE
13	GTEx	Skin Sun Exposed Lower leg	MOV10	0.05	0.02	lasso	5	0.02	1.1e-02	6.7	6.8	7.4e-12	-0.32	0.14	0.57	FALSE
16	METSIM	Adipose	SLC16A1	0.10	0.10	lasso	5	0.10	2.5e-14	-6.7	6.8	8.3e-12	0.02	0.03	0.97	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	WNT2B	0.34	0.40	enet	30	0.42	1.5e-59	6.7	6.5	7.6e-11	-0.15	0.11	0.89	FALSE
7	GTEx	Esophagus Muscularis	SLC16A1	0.11	0.03	lasso	4	0.04	2.9e-03	5.2	-6.4	1.6e-10	-0.14	0.13	0.73	FALSE
5	GTEx	Brain Frontal Cortex BA9	WNT2B	0.29	0.28	lasso	3	0.29	2.6e-08	6.8	6.3	3.6e-10	-0.20	0.12	0.87	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC16A1	0.06	0.01	blup	38	0.02	1.4e-03	-2.7	6.2	4.5e-10	0.04	0.01	0.68	FALSE
8	GTEx	Heart Left Ventricle	SLC16A1	0.08	0.05	lasso	3	0.03	7.3e-03	-6.9	-6.2	7.0e-10	-0.05	0.06	0.67	FALSE
4	GTEx	Brain Cortex	WNT2B	0.36	0.19	lasso	5	0.23	5.5e-07	6.7	6.0	2.0e-09	-0.14	0.12	0.85	FALSE
11	GTEx	Pituitary	ST7L	0.31	0.18	lasso	7	0.18	3.0e-05	4.5	5.9	3.4e-09	-0.23	0.14	0.71	FALSE
3	GTEx	Artery Aorta	WNT2B	0.15	0.01	enet	7	0.01	1.0e-01	-6.0	-5.9	3.8e-09	0.41	0.15	0.40	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	MOV10	0.06	0.06	lasso	7	0.05	9.4e-06	4.6	5.8	5.6e-09	-0.20	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LRIG2	0.05	0.01	bslmm	358	0.03	1.0e-04	-2.9	5.7	1.0e-08	0.00	0.08	0.49	FALSE
14	GTEx	Skin Sun Exposed Lower leg	RHOC	0.07	0.02	lasso	3	0.02	1.5e-02	-5.8	-5.7	1.2e-08	0.40	0.24	0.56	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CAPZA1	0.05	0.06	lasso	3	0.06	1.1e-07	-5.8	-5.7	1.2e-08	0.40	0.98	0.02	FALSE
10	GTEx	Nerve Tibial	RP4-671G15.2	0.07	0.06	lasso	2	0.06	2.9e-05	-5.4	5.7	1.6e-08	-0.40	0.90	0.05	FALSE
9	GTEx	Muscle Skeletal	WNT2B	0.06	0.02	lasso	7	0.03	9.4e-04	-5.9	-5.5	3.5e-08	0.51	0.54	0.05	FALSE
6	GTEx	Breast Mammary Tissue (Male)	WNT2B	0.18	0.07	lasso	6	0.05	2.3e-02	-5.9	-5.5	4.5e-08	0.45	0.08	0.06	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC16A1	0.15	0.05	blup	38	0.05	2.4e-04	-7.1	5.5	4.7e-08	0.06	0.00	0.99	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	SLC16A1	0.12	0.00	lasso	5	0.04	5.0e-03	6.7	-5.4	5.8e-08	0.23	0.06	0.70	FALSE