[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr11:99,859,184-101,559,718

Best TWAS P=2.13e-36 · Best GWAS P=4.81e-35 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARHGAP42 0.08 0.03 enet 14 0.05 2.8e-06 -7.5 -6.5 8.0e-11 0.50 0.98 0.00 FALSE
2 GTEx Artery Aorta ARHGAP42 0.22 0.15 enet 18 0.19 1.7e-10 -12.2 -11.3 7.6e-30 0.86 0.00 1.00 FALSE
3 GTEx Artery Aorta TMEM133 0.30 0.15 enet 34 0.19 7.1e-11 -12.4 -10.0 1.8e-23 0.72 0.00 1.00 FALSE
4 GTEx Artery Tibial ARHGAP42 0.24 0.24 lasso 4 0.24 2.4e-18 -12.4 -12.6 3.3e-36 0.98 0.00 1.00 TRUE
5 GTEx Artery Tibial TMEM133 0.26 0.25 enet 28 0.27 1.3e-21 -12.4 -12.6 2.1e-36 0.94 0.00 1.00 FALSE
6 GTEx Cells Transformed fibroblasts ARHGAP42 0.15 0.10 enet 20 0.08 2.6e-06 4.2 -6.6 4.6e-11 0.46 0.68 0.26 FALSE
7 ROSMAP Brain Pre-frontal Cortex ARHGAP42 0.04 0.00 lasso 2 0.00 1.9e-01 -7.4 -7.1 1.1e-12 0.51 0.11 0.21 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma ARHGAP42 0.04 0.01 blup 266 0.02 1.1e-04 7.0 -8.5 1.4e-17 0.57 0.04 0.87 FALSE