[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr11:99,859,184-101,559,718

Best TWAS P=2.13e-36 · Best GWAS P=4.81e-35 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	ARHGAP42	0.24	0.24	lasso	4	0.24	2.4e-18	-12.4	-12.6	3.3e-36	0.98	0.00	1.00	TRUE
5	GTEx	Artery Tibial	TMEM133	0.26	0.25	enet	28	0.27	1.3e-21	-12.4	-12.6	2.1e-36	0.94	0.00	1.00	FALSE
2	GTEx	Artery Aorta	ARHGAP42	0.22	0.15	enet	18	0.19	1.7e-10	-12.2	-11.3	7.6e-30	0.86	0.00	1.00	FALSE
3	GTEx	Artery Aorta	TMEM133	0.30	0.15	enet	34	0.19	7.1e-11	-12.4	-10.0	1.8e-23	0.72	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	ARHGAP42	0.04	0.01	blup	266	0.02	1.1e-04	7.0	-8.5	1.4e-17	0.57	0.04	0.87	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	ARHGAP42	0.04	0.00	lasso	2	0.00	1.9e-01	-7.4	-7.1	1.1e-12	0.51	0.11	0.21	FALSE
6	GTEx	Cells Transformed fibroblasts	ARHGAP42	0.15	0.10	enet	20	0.08	2.6e-06	4.2	-6.6	4.6e-11	0.46	0.68	0.26	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARHGAP42	0.08	0.03	enet	14	0.05	2.8e-06	-7.5	-6.5	8.0e-11	0.50	0.98	0.00	FALSE