TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
:
←
→
chr11:129,575,976-130,992,111
Best TWAS P=5.45e-16 · Best GWAS P=3.52e-16 conditioned to 0.0472
129.6M
129.8M
130M
130.2M
130.4M
130.6M
130.8M
131M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
ADAMTS8
0.06
0.02
lasso
3
0.02
1.0e-03
-8.2
8.1
5.4e-16
-0.90
0
0.98
TRUE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ADAMTS8
0.04
0.03
enet
8
0.03
8.5e-05
-8.2
6.8
1.5e-11
-0.82
0
0.96
FALSE
1
ROSMAP
Brain Pre-frontal Cortex
ADAMTS8
0.12
0.09
lasso
5
0.08
4.0e-10
-5.6
-5.3
1.3e-07
0.44
1
0.00
FALSE