[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr12:49,780,778-51,912,062

Best TWAS P=1.91e-15 · Best GWAS P=1.75e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Testis	CERS5	0.12	0.06	lasso	6	0.07	4.0e-04	8.0	8.0	1.9e-15	0.98	0.01	0.94	TRUE
21	GTEx	Whole Blood	RP4-605O3.4	0.04	0.04	lasso	4	0.01	1.5e-02	7.8	7.7	1.3e-14	1.00	0.01	0.97	FALSE
15	GTEx	Prostate	CERS5	0.19	0.08	lasso	4	0.02	1.2e-01	7.8	7.7	1.7e-14	0.97	0.02	0.74	FALSE
13	GTEx	Nerve Tibial	CERS5	0.31	0.28	enet	20	0.36	2.2e-26	8.0	7.2	6.4e-13	0.90	0.00	1.00	FALSE
14	GTEx	Nerve Tibial	RP4-605O3.4	0.11	0.00	lasso	3	0.00	1.7e-01	7.9	7.0	3.3e-12	0.84	0.01	0.93	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIMA1	0.08	0.10	blup	59	0.10	1.8e-11	7.2	-6.8	9.5e-12	-0.90	0.30	0.70	FALSE
17	GTEx	Testis	SMARCD1	0.22	0.10	enet	22	0.10	2.6e-05	5.5	-6.7	1.9e-11	-0.85	0.01	0.98	FALSE
7	GTEx	Brain Cerebellar Hemisphere	RP4-605O3.4	0.18	0.12	enet	14	0.10	1.5e-03	8.0	6.6	5.4e-11	0.91	0.02	0.90	FALSE
6	GTEx	Artery Tibial	RP4-605O3.4	0.04	0.01	lasso	4	0.00	3.2e-01	7.9	6.5	9.2e-11	0.96	0.02	0.94	FALSE
12	GTEx	Muscle Skeletal	ATF1	0.09	0.06	lasso	5	0.07	5.0e-07	-6.1	-6.4	1.5e-10	-0.61	0.14	0.86	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DIP2B	0.11	0.10	enet	16	0.13	2.6e-15	5.7	6.3	3.3e-10	0.64	1.00	0.00	FALSE
10	GTEx	Heart Atrial Appendage	CERS5	0.14	0.03	lasso	6	0.02	4.2e-02	8.0	6.3	3.4e-10	0.88	0.04	0.93	FALSE
19	GTEx	Thyroid	LIMA1	0.08	0.06	enet	18	0.06	1.7e-05	7.2	6.1	8.3e-10	0.68	0.15	0.55	FALSE
3	GTEx	Artery Aorta	ATF1	0.26	0.29	lasso	2	0.28	1.5e-15	-6.1	-6.1	9.7e-10	-0.52	0.44	0.56	FALSE
9	GTEx	Esophagus Muscularis	ATF1	0.15	0.17	lasso	2	0.16	7.5e-10	-6.1	-6.1	1.0e-09	-0.53	0.46	0.54	FALSE
5	GTEx	Artery Tibial	ATF1	0.24	0.26	lasso	7	0.25	2.7e-19	-6.1	-6.0	1.8e-09	-0.52	0.46	0.54	FALSE
11	GTEx	Muscle Skeletal	DIP2B	0.03	0.04	lasso	6	0.04	1.1e-04	-6.1	-5.9	2.9e-09	-0.53	0.80	0.12	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	ATF1	0.15	0.15	lasso	4	0.14	7.8e-06	-5.9	-5.8	5.0e-09	-0.53	0.43	0.39	FALSE
22	YFS	Blood	ATF1	0.05	0.07	lasso	9	0.07	2.0e-21	5.2	5.8	5.1e-09	0.69	0.98	0.02	FALSE
16	GTEx	Skin Sun Exposed Lower leg	SMARCD1	0.07	0.02	lasso	2	0.03	1.4e-03	-4.7	-5.7	1.0e-08	-0.70	0.06	0.80	FALSE
4	GTEx	Artery Coronary	ATF1	0.20	0.09	lasso	4	0.05	1.2e-02	-6.1	-5.7	1.1e-08	-0.51	0.19	0.30	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	C12orf62	0.01	0.00	blup	47	0.00	4.6e-02	-3.5	-5.5	4.9e-08	-0.82	0.02	0.46	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	C12orf62	0.06	0.02	blup	47	0.05	1.8e-05	-2.7	-5.4	6.1e-08	-0.82	0.04	0.95	FALSE
2	GTEx	Adipose Subcutaneous	ATF1	0.07	0.05	enet	14	0.04	3.1e-04	-6.1	-5.3	1.4e-07	-0.55	0.43	0.54	FALSE
20	GTEx	Thyroid	CERS5	0.09	0.04	lasso	9	0.04	3.7e-04	-3.5	5.3	1.4e-07	0.79	0.08	0.91	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATF1	0.03	0.04	lasso	1	0.04	6.3e-05	5.2	-5.2	1.9e-07	-0.62	0.34	0.49	FALSE