TWAS
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Usage
Models
Genes
Traits
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Traits
:
Diastolic blood pressure, automated reading
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chr16:1,381,714-2,713,729
Best TWAS P=7.82e-08 · Best GWAS P=1.78e-08 conditioned to 0.0832
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
SLC9A3R2
0.15
0.09
enet
7
0.10
7.8e-12
-5.5
5.4
7.8e-08
-0.93
0
1
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
SLC9A3R2
0.16
0.11
lasso
6
0.12
6.3e-15
-5.6
5.2
2.1e-07
-0.97
0
1
FALSE