[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr15:90,712,555-92,135,418

Best TWAS P=4.05e-28 · Best GWAS P=4.79e-24 conditioned to 0.932

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	FES	0.06	0.05	blup	46	0.07	7.4e-14	10.1	-11.0	4.0e-28	-0.88	0.00	1.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FURIN	0.12	0.14	lasso	2	0.13	1.2e-15	-5.6	5.5	2.9e-08	0.62	1.00	0.00	TRUE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	FES	0.12	0.09	lasso	5	0.08	4.1e-09	10.1	-10.8	2.8e-27	-0.95	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	FES	0.30	0.30	lasso	7	0.32	1.3e-31	10.1	-10.7	6.3e-27	-0.95	0.00	1.00	FALSE
3	GTEx	Artery Tibial	FES	0.16	0.04	lasso	5	0.05	4.8e-05	8.8	-10.3	1.1e-24	-0.89	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	FES	0.05	0.04	lasso	2	0.04	2.2e-05	10.1	-10.3	1.1e-24	-0.95	0.00	1.00	FALSE
5	GTEx	Lung	FES	0.24	0.07	lasso	6	0.05	5.1e-05	8.8	-10.2	1.3e-24	-0.90	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FES	0.06	0.03	blup	46	0.05	5.6e-06	8.9	-10.2	1.8e-24	-0.78	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FES	0.32	0.26	lasso	2	0.25	2.0e-09	10.1	-10.1	6.9e-24	-0.96	0.00	1.00	FALSE
4	GTEx	Cells Transformed fibroblasts	FES	0.28	0.17	enet	21	0.20	2.8e-15	10.1	-10.1	7.7e-24	-0.92	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FES	0.13	0.16	lasso	2	0.14	6.1e-10	10.1	-9.9	2.7e-23	-0.99	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FES	0.06	0.05	blup	46	0.06	1.9e-05	8.8	-9.9	6.0e-23	-0.74	0.02	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	FES	0.21	0.09	lasso	5	0.05	1.3e-03	10.1	-9.8	6.7e-23	-0.99	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FES	0.08	0.07	enet	7	0.08	4.2e-09	10.1	-9.7	4.2e-22	-0.93	0.00	1.00	FALSE
7	GTEx	Thyroid	FES	0.33	0.19	lasso	6	0.18	4.3e-14	9.4	-9.5	1.9e-21	-0.95	0.01	0.99	FALSE
6	GTEx	Skin Sun Exposed Lower leg	FES	0.09	0.04	lasso	5	0.04	1.4e-04	10.1	-9.4	4.8e-21	-0.91	0.00	0.99	FALSE
8	METSIM	Adipose	FES	0.08	0.06	lasso	3	0.05	6.8e-08	8.9	-8.8	9.3e-19	-0.88	0.14	0.86	FALSE
16	The Cancer Genome Atlas	Glioblastoma Multiforme	FES	0.12	0.06	enet	6	0.06	5.7e-03	8.9	-8.8	1.1e-18	-0.80	0.01	0.80	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	FES	0.08	0.07	blup	46	0.06	3.4e-04	8.1	-8.7	3.4e-18	-0.84	0.05	0.86	FALSE
23	The Cancer Genome Atlas	Stomach Adenocarcinoma	FES	0.04	0.01	blup	46	0.02	1.7e-02	8.8	-8.7	4.3e-18	-0.75	0.01	0.54	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FES	0.06	0.02	blup	46	0.02	2.4e-02	10.1	-8.5	1.5e-17	-0.81	0.00	0.90	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FES	0.10	0.07	enet	5	0.05	2.8e-06	8.7	-8.4	5.5e-17	-0.70	0.85	0.14	FALSE
9	YFS	Blood	FES	0.31	0.11	enet	77	0.22	1.2e-68	10.1	-7.5	6.7e-14	-0.61	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	HDDC3	0.05	0.03	blup	59	0.03	1.3e-03	-4.3	-5.8	6.8e-09	-0.33	0.03	0.09	FALSE
10	YFS	Blood	FURIN	0.11	0.03	enet	37	0.06	8.3e-19	-5.6	-5.3	1.4e-07	-0.48	1.00	0.00	FALSE