[Hub]/) : Traits : Systolic blood pressure, automated reading :

chr1:7,715,776-9,571,422

Best TWAS P=2.32e-11 · Best GWAS P=9.29e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 6.3 6.6 4.2e-11 0.97 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous RP5-1115A15.1 0.14 0.07 enet 20 0.10 2.6e-08 -5.7 6.0 1.9e-09 0.79 0.05 0.95 FALSE
3 GTEx Adipose Visceral Omentum RERE 0.22 0.17 lasso 5 0.17 5.2e-09 -5.5 5.2 2.5e-07 0.63 0.21 0.79 FALSE
4 GTEx Breast Mammary Tissue RERE 0.19 0.08 enet 10 0.14 8.0e-08 6.4 5.5 3.8e-08 0.80 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 6.3 6.3 2.6e-10 0.98 0.01 0.98 FALSE
6 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 6.5 6.5 8.8e-11 1.00 0.01 0.99 FALSE
7 GTEx Esophagus Mucosa RERE 0.13 0.16 lasso 3 0.16 7.2e-11 -5.5 5.5 4.6e-08 0.64 0.63 0.37 FALSE
8 GTEx Esophagus Mucosa RP5-1115A15.1 0.06 0.06 lasso 4 0.05 3.0e-04 -5.5 5.4 5.3e-08 0.68 0.06 0.84 FALSE
9 GTEx Lung RP5-1115A15.1 0.05 0.08 lasso 1 0.07 1.0e-05 -5.7 5.7 1.1e-08 0.65 0.21 0.66 FALSE
10 GTEx Nerve Tibial RERE 0.12 0.09 enet 16 0.11 5.6e-08 5.8 5.8 6.6e-09 0.90 0.02 0.98 FALSE
11 GTEx Pancreas RERE 0.11 0.12 lasso 4 0.07 5.9e-04 6.5 6.7 2.3e-11 0.98 0.01 0.97 TRUE
12 GTEx Thyroid RP5-1115A15.1 0.09 0.12 lasso 2 0.09 1.5e-07 -5.7 5.7 9.4e-09 0.68 0.39 0.61 FALSE
13 GTEx Whole Blood RERE 0.19 0.15 lasso 4 0.13 2.7e-12 -5.5 5.7 1.3e-08 0.69 0.68 0.32 FALSE
14 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 6.3 6.1 1.4e-09 0.89 0.01 0.99 FALSE
15 ROSMAP Brain Pre-frontal Cortex RERE 0.15 0.15 lasso 7 0.15 1.5e-18 6.4 6.4 1.4e-10 0.96 0.01 0.99 FALSE
16 YFS Blood RERE 0.09 0.15 lasso 4 0.16 5.7e-49 -5.6 6.2 7.6e-10 0.74 0.46 0.54 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma RERE 0.02 0.03 lasso 2 0.03 4.7e-07 -5.6 5.5 5.1e-08 0.63 0.46 0.51 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma RERE 0.22 0.04 lasso 10 0.08 4.1e-04 -5.5 6.3 2.1e-10 0.85 0.02 0.95 FALSE