Best TWAS P=2.93e-07 · Best GWAS P=1.32e-06 conditioned to 0.000295
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | NEK4 | 0.11 | 0.10 | enet | 11 | 0.12 | 2.1e-09 | -3.5 | -5.1 | 3.0e-07 | 0.36 | 0.19 | 0.46 | FALSE |
| 2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | TMEM110 | 0.33 | 0.15 | enet | 10 | 0.16 | 4.6e-05 | 3.1 | 5.1 | 2.9e-07 | -0.26 | 0.00 | 0.02 | TRUE |