Best TWAS P=1.18e-08 · Best GWAS P=1.26e-07 conditioned to 0.391
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | FIBP | 0.11 | 0.04 | lasso | 4 | 0.04 | 1.2e-03 | 4.8 | 5.2 | 1.9e-07 | 0.89 | 0.02 | 0.96 | FALSE |
| 2 | METSIM | Adipose | FIBP | 0.05 | 0.02 | blup | 344 | 0.02 | 1.0e-03 | 4.0 | 5.5 | 3.3e-08 | 0.72 | 0.07 | 0.90 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CTSW | 0.06 | 0.03 | bslmm | 328 | 0.03 | 3.6e-05 | 3.9 | -5.3 | 1.1e-07 | -0.44 | 0.25 | 0.48 | FALSE |
| 4 | YFS | Blood | FIBP | 0.04 | 0.02 | bslmm | 343 | 0.03 | 6.4e-09 | 4.0 | 5.4 | 8.2e-08 | 0.48 | 0.45 | 0.42 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RNASEH2C | 0.05 | 0.00 | blup | 32 | 0.02 | 1.1e-04 | 2.8 | -5.5 | 4.1e-08 | -0.12 | 0.00 | 0.01 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SIPA1 | 0.06 | 0.04 | blup | 43 | 0.05 | 4.6e-06 | -4.4 | 5.7 | 1.2e-08 | 0.11 | 0.01 | 0.96 | TRUE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RNASEH2C | 0.15 | 0.05 | blup | 32 | 0.05 | 3.1e-06 | 2.8 | -5.4 | 5.9e-08 | -0.11 | 0.00 | 0.04 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SIPA1 | 0.04 | 0.00 | blup | 43 | 0.02 | 6.2e-03 | -5.1 | 5.7 | 1.4e-08 | 0.12 | 0.00 | 0.47 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SNX32 | 0.15 | 0.11 | blup | 60 | 0.15 | 6.0e-17 | 4.7 | 5.6 | 2.0e-08 | 0.72 | 0.04 | 0.94 | TRUE |
| 10 | The Cancer Genome Atlas | Lung Adenocarcinoma | SNX32 | 0.14 | 0.09 | blup | 60 | 0.13 | 8.8e-15 | 4.7 | 5.4 | 8.5e-08 | 0.64 | 0.17 | 0.76 | FALSE |
| 11 | The Cancer Genome Atlas | Thyroid Carcinoma | FIBP | 0.04 | 0.00 | blup | 45 | 0.02 | 8.0e-03 | 4.8 | 5.4 | 5.4e-08 | 0.71 | 0.01 | 0.37 | FALSE |