Best TWAS P=1.96e-09 · Best GWAS P=3.4e-07 conditioned to 0.677
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | EML1 | 0.14 | 0.08 | lasso | 7 | 0.11 | 4.9e-09 | 4.5 | 6.0 | 2.0e-09 | -0.82 | 0.02 | 0.97 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | CYP46A1 | 0.20 | 0.00 | blup | 65 | 0.08 | 1.6e-03 | -2.1 | 5.6 | 2.1e-08 | -0.35 | 0.02 | 0.06 | TRUE |