Best TWAS P=1.16e-11 · Best GWAS P=4.19e-15 conditioned to 0.227
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | ABHD17C | 0.13 | 0.01 | enet | 24 | 0.00 | 1.3e-01 | 3.9 | 6.2 | 7.7e-10 | 0.26 | 0.15 | 0.04 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 6.9 | -6.8 | 1.2e-11 | -0.84 | 0.14 | 0.86 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -4.2 | -6.0 | 1.4e-09 | -0.80 | 0.04 | 0.53 | FALSE |