[Hub]/) : Traits : Systolic blood pressure, automated reading :

chr16:24,042,724-25,620,010

Best TWAS P=4.49e-16 · Best GWAS P=7.85e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose SLC5A11 0.23 0.28 lasso 10 0.28 1.6e-42 -7.67 -7.6 2.4e-14 0.97 0.01 0.99 FALSE
2 NTR Blood TNRC6A 0.03 0.00 bslmm 459 0.00 2.5e-02 0.99 -5.5 4.1e-08 0.44 0.06 0.15 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma SLC5A11 0.17 0.21 lasso 4 0.21 1.7e-17 -7.15 -7.4 1.4e-13 0.96 0.01 0.99 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma SLC5A11 0.12 0.17 enet 9 0.18 1.1e-35 -7.66 -7.4 1.5e-13 0.96 0.00 1.00 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma SLC5A11 0.27 0.24 lasso 6 0.24 4.5e-12 -7.65 -7.8 6.0e-15 0.97 0.00 1.00 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma SLC5A11 0.27 0.21 lasso 2 0.20 5.2e-12 -7.65 -7.6 2.0e-14 0.97 0.00 1.00 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC5A11 0.13 0.15 enet 8 0.15 6.6e-17 -7.77 -6.7 2.0e-11 0.92 0.00 1.00 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC5A11 0.07 0.07 enet 7 0.06 1.7e-07 -7.77 -7.2 4.7e-13 0.95 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma SLC5A11 0.14 0.20 enet 9 0.20 2.2e-23 -7.68 -7.5 5.0e-14 0.98 0.00 1.00 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC5A11 0.06 0.05 lasso 1 0.05 4.9e-06 -7.68 -7.7 1.5e-14 0.97 0.00 1.00 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC5A11 0.14 0.02 blup 62 0.07 1.4e-05 -7.66 -6.8 1.2e-11 0.71 0.00 0.98 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma SLC5A11 0.30 0.33 lasso 2 0.32 2.8e-14 -7.77 -8.1 4.5e-16 0.98 0.00 1.00 TRUE
13 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SLC5A11 0.54 0.32 lasso 6 0.30 1.8e-12 -7.15 -7.3 2.8e-13 0.95 0.00 1.00 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma SLC5A11 0.26 0.28 lasso 6 0.31 1.0e-32 -7.66 -7.4 1.5e-13 0.95 0.00 1.00 FALSE
15 The Cancer Genome Atlas Soft Tissue Sarcoma SLC5A11 0.17 0.21 lasso 3 0.18 4.9e-11 -7.77 -7.8 6.5e-15 1.00 0.00 1.00 FALSE
16 The Cancer Genome Atlas Skin Cutaneous Melanoma SLC5A11 0.20 0.05 lasso 4 0.04 2.8e-02 -7.68 -7.7 1.8e-14 0.95 0.00 0.84 FALSE
17 The Cancer Genome Atlas Stomach Adenocarcinoma SLC5A11 0.12 0.08 enet 7 0.07 7.0e-06 -7.66 -6.9 4.3e-12 0.93 0.00 1.00 FALSE
18 The Cancer Genome Atlas Testicular Germ Cell Tumors SLC5A11 0.21 0.10 lasso 5 0.07 2.2e-03 -7.66 -7.4 1.4e-13 0.97 0.00 0.98 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma SLC5A11 0.35 0.44 lasso 4 0.44 4.2e-47 -7.66 -7.7 1.6e-14 0.99 0.00 1.00 FALSE
20 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma SLC5A11 0.24 0.15 lasso 3 0.14 1.1e-04 -7.68 -7.7 1.6e-14 0.97 0.00 0.97 FALSE