[Hub]/) : Traits : Systolic blood pressure, automated reading :

chr16:69,337,091-71,292,172

Best TWAS P=9.73e-09 · Best GWAS P=2.58e-07 conditioned to 0.109

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RP11-296I10.6 0.13 0.09 enet 18 0.04 1.4e-02 -4.3 -5.2 2.4e-07 -0.73 0.05 0.72 FALSE
2 GTEx Artery Aorta SF3B3 0.05 0.01 enet 9 0.01 6.4e-02 5.2 5.1 2.9e-07 0.95 0.02 0.84 FALSE
3 GTEx Brain Cerebellum PDPR 0.23 0.06 enet 20 0.11 3.7e-04 -4.3 -5.3 1.2e-07 -0.58 0.03 0.51 FALSE
4 GTEx Breast Mammary Tissue PDXDC2P 0.55 0.24 enet 35 0.36 1.4e-19 -4.4 -5.3 1.4e-07 -0.76 0.06 0.92 FALSE
5 GTEx Breast Mammary Tissue (Female) PDXDC2P 0.44 0.14 enet 16 0.16 1.9e-05 -4.6 -5.3 1.4e-07 -0.78 0.05 0.82 FALSE
6 GTEx Colon Transverse PDXDC2P 0.52 0.28 enet 24 0.33 2.7e-16 4.6 -5.3 1.0e-07 -0.75 0.04 0.94 FALSE
7 GTEx Esophagus Gastroesophageal Junction RP11-296I10.6 0.26 0.22 enet 15 0.20 7.9e-08 -4.3 -5.3 1.2e-07 -0.87 0.04 0.93 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic PDXDC2P 0.36 0.22 enet 24 0.24 4.1e-13 4.6 -5.2 2.0e-07 -0.75 0.04 0.94 FALSE
9 GTEx Stomach RP11-296I10.6 0.24 0.15 enet 14 0.16 4.5e-08 -4.3 -5.7 9.7e-09 -0.70 0.10 0.84 TRUE
10 GTEx Thyroid PDXDC2P 0.41 0.27 lasso 10 0.30 5.0e-23 4.7 -5.5 3.0e-08 -0.87 0.04 0.94 FALSE
11 GTEx Whole Blood PDXDC2P 0.16 0.05 lasso 3 0.07 9.0e-07 -3.7 -5.2 2.0e-07 -0.73 0.09 0.86 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma COG4 0.25 -0.01 enet 6 0.05 4.4e-03 -2.8 5.5 4.2e-08 0.66 0.01 0.38 FALSE
13 The Cancer Genome Atlas Rectum Adenocarcinoma COG4 0.33 0.09 enet 12 0.15 2.5e-04 4.9 5.3 9.3e-08 0.75 0.01 0.88 FALSE